Zobrazeno 1 - 10
of 172
pro vyhledávání: '"L. Mowbray"'
Autor:
Jessica L. Mowbray, MBCHB, Gabriela Moreno, MD, Christiaan G.M. Albers, MD, Peter Poon, FRACS
Publikováno v:
JSES Reviews, Reports, and Techniques, Vol 1, Iss 4, Pp 381-388 (2021)
Background: Acromioclavicular (AC) horizontal instability is a problem affecting not only young athletic patients after a trauma to the AC joint but also older patients who have undergone distal clavicle resection. It may cause pain and poor function
Externí odkaz:
https://doaj.org/article/22e4d9e8eb864353ab18358acf487c18
Autor:
Lu Lu, Linda Åkerbladh, Shabbir Ahmad, Vivek Konda, Sha Cao, Anthony Vocat, Louis Maes, Stewart T. Cole, Diarmaid Hughes, Mats Larhed, Peter Brandt, Anders Karlén, Sherry L. Mowbray
Publikováno v:
ACS Infectious Diseases
Type II NADH dehydrogenase (NDH-2) is an essential component of electron transfer in many microbial pathogens but has remained largely unexplored as a potential drug target. Previously, quinolinyl pyrimidines were shown to inhibit Mycobacterium tuber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a39718c8f3bfe61b328322f78be178
https://doi.org/10.1021/acsinfecdis.1c00413
https://doi.org/10.1021/acsinfecdis.1c00413
Publikováno v:
British Journal of Surgery. 109
Introduction All male patients with urinary tract infections (UTI) at this large district general hospital are admitted under the care of the urology department. This audit aims to establish how many male patients over the age of 70 with a diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e6a214adc3719393ad35f92aab1182
https://doi.org/10.1093/bjs/znac269.515
https://doi.org/10.1093/bjs/znac269.515
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 13161-13176 (2014)
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Globally, tuberculosis is second only to AIDS in mortality and the disease is responsible for over 1.3 million deaths each year. The impractically long treatment schedules (g
Externí odkaz:
https://doaj.org/article/34507a3ea9db4c68baafa77ce136dbd1
Autor:
Y. Tajima, D.M. Vasilescu, C.Y. Seow, S. Dong, M. Tsutsui, C.Y. Cheung, I. Welch, L. Mowbray, B. Imlach, J. Hodasova, R. Hildebrandt, B. Ryomoto, E. Goodacre, K. Singh, K. Wolff, E. Elizur, D.D. Sin
Publikováno v:
A63. MECHANISMS AND SUPPORT FOR THE DYSFUNCTIONAL LUNG.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa7717e2df7af14767d0a380bf2c909
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2020
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2020
Autor:
Lu, Lu, Linda, Åkerbladh, Shabbir, Ahmad, Vivek, Konda, Sha, Cao, Anthony, Vocat, Louis, Maes, Stewart T, Cole, Diarmaid, Hughes, Mats, Larhed, Peter, Brandt, Anders, Karlén, Sherry L, Mowbray
Publikováno v:
ACS infectious diseases. 8(3)
Type II NADH dehydrogenase (NDH-2) is an essential component of electron transfer in many microbial pathogens but has remained largely unexplored as a potential drug target. Previously, quinolinyl pyrimidines were shown to inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9651377aab8d986bbc3221d81d706a3a
https://pubmed.ncbi.nlm.nih.gov/35184552
https://pubmed.ncbi.nlm.nih.gov/35184552
Autor:
Natalia Szałaj, Andrea Benediktsdottir, Dominika Rusin, Anders Karlén, Sherry L. Mowbray, Anna Więckowska
The ever-increasing number of bacteria resistant to the currently available antibacterial agents is a great medical problem today, and new antibiotics with novel mechanisms of action are urgently needed. Among the validated antibacterial drug targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce85782c3d59e4bbb184325456d7b9b
https://ruj.uj.edu.pl/xmlui/handle/item/297175
https://ruj.uj.edu.pl/xmlui/handle/item/297175
Autor:
Sha Cao, Diarmaid Hughes, Andrea Benediktsdottir, Anders Karlén, Sherry L. Mowbray, Anja Sandström, Lu Lu, Edouard Zamaratski
Oligopeptide boronates with a lipophilic tail are known to inhibit the type I signal peptidase in E. coli, which is a promising drug target for developing novel antibiotics. Antibacterial activity depends on these oligopeptides having a cationic modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81bc1a93d6f4063bfe71b7fc5ad074d
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-450022
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-450022
Autor:
Anders Karlén, Máté Erdélyi, Charles Hedgecock, Andrea Benediktsdottir, Gustav Olanders, Peter Brandt, Edouard Zamaratski, Sherry L. Mowbray, Lu Lu, Sha Cao, Diarmaid Hughes, Natalia Szałaj
Publikováno v:
European Journal of Medicinal Chemistry. 157:1346-1360
Type I signal peptidase, with its vital role in bacterial viability, is a promising but underexploited antibacterial drug target. In the light of steadily increasing rates of antimicrobial resistance, we have developed novel macrocyclic lipopeptides,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1842e832737a92e7de3e08d2315ca3
https://doi.org/10.1016/j.ejmech.2018.08.086
https://doi.org/10.1016/j.ejmech.2018.08.086
Autor:
János Pató, Jan Rybniker, Gaëlle S. Kolly, Rita Székely, Neeraj Dhar, Zuzana Palčeková, Anthony Vocat, Digby F. Warner, Júlia Zemanová, Monica G Rengifo, Priscille Brodin, John D. McKinney, Adrian Suarez Covarrubias, Vinayak Singh, François Signorino-Gelo, Joseph Buechler, Sherry L. Mowbray, Ruben C. Hartkoorn, José A. Aínsa, Stewart T. Cole, Vincent Delorme, Martin Forbak, Isabella Santi, Joanna C. Evans, Liliana Rodrigues, György Kéri, Katarína Mikušová, Kai Johnsson, Jana Korduláková, Graham Knott, Valerie Mizrahi
Publikováno v:
Molecular Microbiology. 103:13-25
There is an urgent need to discover new anti-tubercular agents with novel mechanisms of action in order to tackle the scourge of drug-resistant tuberculosis. Here, we report the identification of such a molecule - an AminoPYrimidine-Sulfonamide (APYS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c108991780420cb8426b100589be6471
https://doi.org/10.1111/mmi.13535
https://doi.org/10.1111/mmi.13535