Zobrazeno 1 - 10
of 373
pro vyhledávání: '"L. Motola"'
Publikováno v:
Journal of Forensic Sciences. 65:1698-1703
Dermestid beetles (Dermestes maculatus De Geer 1774) are small carrion insects characterized by a rounded or oval-shaped body and white abdomen with black markings. Given their natural propensity to consume soft tissue throughout various stages of de
Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal PermeabilitySummary
Autor:
Jay Luther, John J. Garber, Hamed Khalili, Maneesh Dave, Shyam Sundhar Bale, Rohit Jindal, Daniel L. Motola, Sanjana Luther, Stefan Bohr, Soung Won Jeoung, Vikram Deshpande, Gurminder Singh, Jerrold R. Turner, Martin L. Yarmush, Raymond T. Chung, Suraj J. Patel
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 2, Pp 222-232.e2 (2015)
Background & Aims: Emerging data suggest that changes in intestinal permeability and increased gut microbial translocation contribute to the inflammatory pathway involved in nonalcoholic steatohepatitis (NASH) development. Numerous studies have inves
Externí odkaz:
https://doaj.org/article/af64a40e688a4485a116866d0e616577
Autor:
Alan C. Mullen, Bryan C. Fuchs, Joshua V. Pondick, Irina Bronova, Yusuf A. Hannun, Raymond T. Chung, Chan Zhou, Sarani Ghoshal, Samuel R. York, Nicolas Coant, Evgeny Berdyshev, Jennifer Y. Chen, Cungui Mao, Jae Kyo Yi, Benjamin Newcomb, Daniel L. Motola, Kenneth K. Tanabe
Publikováno v:
Scientific Reports
Activation of hepatic stellate cells (HSCs) in response to injury is a key step in hepatic fibrosis, and is characterized by trans-differentiation of quiescent HSCs to HSC myofibroblasts, which secrete extracellular matrix proteins responsible for th
Autor:
Andrew Yang, Raymond T. Chung, Esperance A. Schaefer, Cynthia Brisac, Lee F. Peng, Christina Mark, Daniel L. Motola, Dahlene N. Fusco, Clary B. Clish, Shadi Salloum, Amy Deik, Wenyu Lin, James Meixiong
Publikováno v:
World Journal of Gastroenterology
AIM To characterize the role of apolipoprotein B100 (apoB100) in hepatitis C viral (HCV) infection. METHODS In this study, we utilize a gene editing tool, transcription activator-like effector nucleases (TALENs), to generate human hepatoma cells with
Autor:
Alan C. Mullen, Raymond T. Chung, Jennifer Y. Chen, Chan Zhou, Samuel R. York, Daniel L. Motola, Joshua V. Pondick
Publikováno v:
Genome Medicine
Background Hepatic fibrosis is the underlying cause of cirrhosis and liver failure in nearly every form of chronic liver disease, and hepatic stellate cells (HSCs) are the primary cell type responsible for fibrosis. Long noncoding RNAs (lncRNAs) are
Autor:
David J. Mangelsdorf, Yidong Shen, Lilia Magomedova, Joshua Wollam, Adam Antebi, Daniel L. Motola, Carolyn L. Cummins, Veerle Rottiers, Daniel B. Magner
Publikováno v:
Aging Cell. 10:879-884
Summary Bile acids are cholesterol-derived signaling molecules that regulate mammalian metabolism through sterol-sensing nuclear receptor transcription factors. In C. elegans, bile acid-like steroids called dafachronic acids (DAs) control development
Autor:
H. Eric Xu, Daniel L. Motola, David J. Mangelsdorf, Kamalesh K. Sharma, Zhu Wang, John M. Hawdon, Xin Gao, Richard J. Auchus, James B. Lok, Aoife Conneely, Kelly Suino-Powell, X. Edward Zhou, Steven A. Kliewer, Craig M. Ogata
Publikováno v:
Proceedings of the National Academy of Sciences. 106:9138-9143
Nematode parasitism is a worldwide health problem resulting in malnutrition and morbidity in over 1 billion people. The molecular mechanisms governing infection are poorly understood. Here, we report that an evolutionarily conserved nuclear hormone r
Autor:
Costa, Mafalda1 (AUTHOR) helena.menezesmagalhaes@ulsm.min-saude.pt, Lopes Fernandes, Catarina1 (AUTHOR) mafalda.teixeiracosta@ulsm.min-saude.pt, Magalhães, Helena1 (AUTHOR)
Publikováno v:
Cancers. Dec2024, Vol. 16 Issue 23, p4036. 24p.
Autor:
He, MingLiu1 (AUTHOR), Yu, QiFan1 (AUTHOR), Xiao, Han1 (AUTHOR), Dong, HengDa1 (AUTHOR), Li, DaZhuang1 (AUTHOR), Gu, WenGuang1 (AUTHOR) wenguang0912@163.com
Publikováno v:
BMC Musculoskeletal Disorders. 11/25/2024, Vol. 25 Issue 1, p1-13. 13p.
Autor:
Mallardo, Domenico1 (AUTHOR) margaretottaviano@gmail.com, Fordellone, Mario2 (AUTHOR) mario.fordellone@unicampania.it, Ottaviano, Margaret1 (AUTHOR) giuseppina.marano@istitutotumori.na.it, Marano, Giuseppina1 (AUTHOR) dott.mariagrazia.vitale@gmail.com, Vitale, Maria Grazia1 (AUTHOR) mario.mallardo39@gmail.com, Mallardo, Mario1 (AUTHOR) mariagrazia.capasso@istitutotumori.na.it, Capasso, Mariagrazia1 (AUTHOR) teresa.decristofaro@istitutotumori.na.it, De Cristofaro, Teresa1 (AUTHOR) marilenacapone@gmail.com, Capone, Mariaelena1 (AUTHOR) t.meinardi97@gmail.com, Meinardi, Teresa1 (AUTHOR) miriam.paone@gmail.com, Paone, Miriam1 (AUTHOR) p.sabatelli@istitutotumori.na.it, Sabatelli, Patrizia1 (AUTHOR) ester.simeone@gmail.com, De Filippi, Rosaria3 (AUTHOR) rdefilip@unina.it, Cesano, Alessandra4 (AUTHOR) acesano@essapharma.com, Cavalcanti, Ernesta5 (AUTHOR) e.cavalcanti@istitutotumori.na.it, Caracò, Corrado6 (AUTHOR) corrado.caraco@istitutotumori.na.it, Warren, Sarah4 (AUTHOR) swarren@nanostring.com, Budillon, Alfredo7 (AUTHOR) a.budillon@istitutotumori.na.it, Simeone, Ester1 (AUTHOR) paolo.ascierto@gmail.com, Ascierto, Paolo Antonio1 (AUTHOR)
Publikováno v:
International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12439. 12p.