Pharmacokinetic analysis of striatal D2R availability with F-18-DMFP PET in a rodent model of depression

Autor: R. Berti, L. Miguel Telega, N. Steinacker, L. C. Domogalla, M. A. Omrane, G. Blazhenets, L. Frings, J. Brumberg, V. A. Coenen, P. T. Meyer, M. D. Döbrössy, A. C. Eder

Publikováno v: 61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cb13356372ecc5cb88b3bdc94b141ea
https://doi.org/10.1055/s-0043-1766203

Electrophysiological and molecular effects of bilateral deep brain stimulation of the medial forebrain bundle in a rodent model of depression

Autor: F. Bühning, L. Miguel Telega, Y. Tong, J. Pereira, V.A. Coenen, M.D. Döbrössy

Publikováno v: Experimental neurology. 355

Deep Brain Stimulation (DBS) of the Medial Forebrain Bundle (MFB) induces antidepressant effects both clinically and pre-clinically. However, the acute electrophysiological changes induced by MFB DBS remain unknown.The study investigated acute mfb DB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1ff114b8a7970ff10f0f39b5f1883b
https://pubmed.ncbi.nlm.nih.gov/35636499

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Reserpine-induced rat model for depression: Behavioral, physiological and PET-based dopamine receptor availability validation.

Autor: Miguel Telega L; Lab of Stereotaxy and Interventional Neurosciences (SIN), Dept. of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Germany; Department of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Germany; Faculty of Biology, University of Freiburg, Germany; BrainLinks-BrainTools, IMBIT (Institute for Machine-Brain Interfacing Technology), Freiburg, Germany., Berti R; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Blazhenets G; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Domogalla LC; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Freiburg, Germany and German Cancer Research Center, Heidelberg, Germany., Steinacker N; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Freiburg, Germany and German Cancer Research Center, Heidelberg, Germany., Omrane MA; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Meyer PT; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Basics in Neuromodulation, University of Freiburg, Freiburg, Germany., Coenen VA; Lab of Stereotaxy and Interventional Neurosciences (SIN), Dept. of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Germany; Department of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Germany; Center for Basics in Neuromodulation, University of Freiburg, Freiburg, Germany; BrainLinks-BrainTools, IMBIT (Institute for Machine-Brain Interfacing Technology), Freiburg, Germany., Eder AC; Department of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Freiburg, Germany and German Cancer Research Center, Heidelberg, Germany., Döbrössy MD; Lab of Stereotaxy and Interventional Neurosciences (SIN), Dept. of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Germany; Department of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Germany; Faculty of Biology, University of Freiburg, Germany; Center for Basics in Neuromodulation, University of Freiburg, Freiburg, Germany. Electronic address: mate.dobrossy@uniklinik-freiburg.de.

Publikováno v: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2024 Jul 13; Vol. 133, pp. 111013. Date of Electronic Publication: 2024 Apr 16.