Zobrazeno 1 - 10
of 372
pro vyhledávání: '"L. Martindale"'
Autor:
Showkat Ahmad Dar, Sulochan Malla, Vlastimil Martinek, Matthew John Payea, Christopher Tai-Yi Lee, Jessica Martin, Aditya Jignesh Khandeshi, Jennifer L Martindale, Cedric Belair, Manolis Maragkakis
Publikováno v:
eLife, Vol 13 (2024)
Cells react to stress by triggering response pathways, leading to extensive alterations in the transcriptome to restore cellular homeostasis. The role of RNA metabolism in shaping the cellular response to stress is vital, yet the global changes in RN
Externí odkaz:
https://doaj.org/article/34e5ddc7174d41d08480a88894c08ed0
Autor:
Alexander P. L. Martindale, Carrie D. Llewellyn, Richard O. de Visser, Benjamin Ng, Victoria Ngai, Aditya U. Kale, Lavinia Ferrante di Ruffano, Robert M. Golub, Gary S. Collins, David Moher, Melissa D. McCradden, Lauren Oakden-Rayner, Samantha Cruz Rivera, Melanie Calvert, Christopher J. Kelly, Cecilia S. Lee, Christopher Yau, An-Wen Chan, Pearse A. Keane, Andrew L. Beam, Alastair K. Denniston, Xiaoxuan Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The Consolidated Standards of Reporting Trials extension for Artificial Intelligence interventions (CONSORT-AI) was published in September 2020. Since its publication, several randomised controlled trials (RCTs) of AI interventions have been
Externí odkaz:
https://doaj.org/article/a2d27b1908784851a58e618b7b71f7b0
Autor:
Jared A. Rowland, Sarah L. Martindale
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionBlast exposure is an increasingly present occupational hazard for military service members, particularly in modern warfare scenarios. The study of blast exposure in humans is limited by the lack of a consensus definition for blast exposur
Externí odkaz:
https://doaj.org/article/624d1072184d4d5d821a171b6f941de0
Autor:
Alexander P. L. Martindale, Carrie D. Llewellyn, Richard O. de Visser, Benjamin Ng, Victoria Ngai, Aditya U. Kale, Lavinia Ferrante di Ruffano, Robert M. Golub, Gary S. Collins, David Moher, Melissa D. McCradden, Lauren Oakden-Rayner, Samantha Cruz Rivera, Melanie Calvert, Christopher J. Kelly, Cecilia S. Lee, Christopher Yau, An-Wen Chan, Pearse A. Keane, Andrew L. Beam, Alastair K. Denniston, Xiaoxuan Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/8c62a46cdbbb49cf9eb4752d6f008c03
Autor:
Kelsee M. Stromberg, Sarah L. Martindale, William C. Walker, Zhining Ou, Terri K. Pogoda, Shannon R. Miles, Clara E. Dismuke-Greer, Kathleen F. Carlson, Jared A. Rowland, Maya E. O’Neil, Mary Jo Pugh
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
BackgroundBehavioral dyscontrol occurs commonly in the general population and in United States service members and Veterans (SM/V). This condition merits special attention in SM/V, particularly in the aftermath of deployments. Military deployments fr
Externí odkaz:
https://doaj.org/article/2b5be759d66141ccb691d03a7498e434
Autor:
Mary R. Newsome, Sarah L. Martindale, Nicholas Davenport, Emily L. Dennis, Marlene Diaz, Carrie Esopenko, Cooper Hodges, George R. Jackson, Qisheng Liu, Kimbra Kenney, Andrew R. Mayer, Jared A. Rowland, Randall S. Scheibel, Joel L. Steinberg, Brian A. Taylor, David F. Tate, J. Kent Werner, William C. Walker, Elisabeth A. Wilde
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionThe relation between traumatic brain injury (TBI), its acute and chronic symptoms, and the potential for remote neurodegenerative disease is a priority for military research. Structural and functional connectivity (FC) of the basal gangli
Externí odkaz:
https://doaj.org/article/ab20ff0e605e40f1b8cc10a2a6608e62
Autor:
Carlos Anerillas, Allison B. Herman, Rachel Munk, Amanda Garrido, Kwan-Wood Gabriel Lam, Matthew J. Payea, Martina Rossi, Dimitrios Tsitsipatis, Jennifer L. Martindale, Yulan Piao, Krystyna Mazan-Mamczarz, Jinshui Fan, Chang-Yi Cui, Supriyo De, Kotb Abdelmohsen, Rafael de Cabo, Myriam Gorospe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Selective elimination of senescent cells is an approach that has shown promise to ameliorate age-associated pathologies in preclinical models. Here the authors report that BDNF enhances senescent cell viability via TrkB in cultured cells, and that Tr
Externí odkaz:
https://doaj.org/article/e9f4fa8422c44db1b4b81a70d8b5218b
Autor:
Kotb Abdelmohsen, Allison B. Herman, Angelica E. Carr, Charnae’ A. Henry‐Smith, Martina Rossi, Qiong Meng, Jen‐Hao Yang, Dimitrios Tsitsipatis, Alhassan Bangura, Rachel Munk, Jennifer L. Martindale, Carlos J. Nogueras‐Ortiz, Jon Hao, Yi Gong, Yie Liu, Chang‐Yi Cui, Lisa M. Hartnell, Nathan L. Price, Luigi Ferrucci, Dimitrios Kapogiannis, Rafael deCabo, Myriam Gorospe
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 8, Pp n/a-n/a (2023)
Abstract Extracellular vesicles and particles (EVPs) are secreted by organs across the body into different circulatory systems, including the bloodstream, and reflect pathophysiologic conditions of the organ. However, the heterogeneity of EVPs in the
Externí odkaz:
https://doaj.org/article/656efe14d6fe4f1d8168af4c3c74e2f7
Autor:
Allison B. Herman, Dimitrios Tsitsipatis, Carlos Anerillas, Krystyna Mazan-Mamczarz, Angelica E. Carr, Jordan M. Gregg, Mingyi Wang, Jing Zhang, Marc Michel, Charnae’ A. Henry-Smith, Sophia C. Harris, Rachel Munk, Jennifer L. Martindale, Yulan Piao, Jinshui Fan, Julie A. Mattison, Supriyo De, Kotb Abdelmohsen, Robert W. Maul, Toshiko Tanaka, Ann Zenobia Moore, Megan E. DeMouth, Simone Sidoli, Luigi Ferrucci, Yie Liu, Rafael de Cabo, Edward G. Lakatta, Myriam Gorospe
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Senescent vascular smooth muscle cells (VSMCs) accumulate in the vasculature with age and tissue damage and secrete factors that promote atherosclerotic plaque vulnerability and disease. Here, we report increased levels and activity of dipeptidyl pep
Externí odkaz:
https://doaj.org/article/097cd3f88b2846ebbe4f877f1734a991
Autor:
Nathan A. Kimbrel, Melanie E. Garrett, Mariah K. Evans, Clara Mellows, Michelle F. Dennis, Lauren P. Hair, Michael A. Hauser, the VA Mid-Atlantic MIRECC Workgroup, Allison E. Ashley-Koch, Jean C. Beckham, Patrick S. Calhoun, Eric Dedert, Eric B. Elbogen, John A. Fairbank, Robin A. Hurley, Jason D. Kilts, Angela Kirby, Sarah L. Martindale, Christine E. Marx, Scott D. McDonald, Scott D. Moore, Rajendra A. Morey, Jennifer C. Naylor, Jared Rowland, Robert D. Shura, Cindy Swinkels, Larry A. Tupler, Elizabeth E. Van Voorhees, Ruth Yoash-Gantz
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionThe U.S. suicide mortality rate has steadily increased during the past two decades, particularly among military veterans; however, the epigenetic basis of suicidal thoughts and behaviors (STB) remains largely unknown.MethodsTo address thi
Externí odkaz:
https://doaj.org/article/e776522472f847f4b2175f13547ac9c5