Zobrazeno 1 - 10
of 92
pro vyhledávání: '"L. Marcus Wilhelmsson"'
Autor:
Sagar Mahale, Meenakshi Setia, Bharat Prajapati, Santhilal Subhash, Mukesh Pratap Yadav, Subazini Thankaswamy Kosalai, Ananya Deshpande, Jagannath Kuchlyan, Mirco Di Marco, Fredrik Westerlund, L. Marcus Wilhelmsson, Chandrasekhar Kanduri, Meena Kanduri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Using fibroblast growth factor 2 (FGF-2) induced sense and antisense transcripts IER3 and IER3-AS1 as a model system, authors highlight the role of HnRNPK in regulating double strand RNA formation in the loci with overlapping transcripts.
Externí odkaz:
https://doaj.org/article/411814645a2a43f093d137eb408eac1f
Autor:
Jesper R. Nilsson, Tom Baladi, Audrey Gallud, Dženita Baždarević, Malin Lemurell, Elin K. Esbjörner, L. Marcus Wilhelmsson, Anders Dahlén
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract To expand the antisense oligonucleotide (ASO) fluorescence labeling toolbox beyond covalent conjugation of external dyes (e.g. ATTO-, Alexa Fluor-, or cyanine dyes), we herein explore fluorescent base analogues (FBAs) as a novel approach to
Externí odkaz:
https://doaj.org/article/8abf403a3bcb4d9fa1479c960effbb9d
Autor:
Mattias Bood, Anna Wypijewska del Nogal, Jesper R. Nilsson, Fredrik Edfeldt, Anders Dahlén, Malin Lemurell, L. Marcus Wilhelmsson, Morten Grøtli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The aberrant expression of microRNAs (miRs) has been linked to several human diseases. A promising approach for targeting these anomalies is the use of small-molecule inhibitors of miR biogenesis. These inhibitors have the potential to (i) d
Externí odkaz:
https://doaj.org/article/cda9c7e7160e4417b694ff5cf0c29da7
Autor:
Christopher P. Lawson, Anders F. Füchtbauer, Moa S. Wranne, Tristan Giraud, Thomas Floyd, Blaise Dumat, Nicolai K. Andersen, Afaf H. El-Sagheer, Tom Brown, Henrik Gradén, L. Marcus Wilhelmsson, Morten Grøtli
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission to develop bright and useful FBAs for all natural nucleobases, herein we describe
Externí odkaz:
https://doaj.org/article/91467726e61f4f76abb1785ce4f6f727
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 114-129 (2018)
Förster resonance energy transfer (FRET) between a donor nucleobase analogue and an acceptor nucleobase analogue, base–base FRET, works as a spectroscopic ruler and protractor. With their firm stacking and ability to replace the natural nucleic ac
Externí odkaz:
https://doaj.org/article/d356d7533aff4d8ab3ddd02f0ca5e348
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9008 (2021)
Pre-miRNA-377 is a hairpin-shaped regulatory RNA associated with heart failure. Here, we use single-molecule optical tweezers to unzip pre-miRNA-377 and study its stability and dynamics. We show that magnesium ions have a strong stabilizing effect, a
Externí odkaz:
https://doaj.org/article/4eabb0c60e764564b19a2b3e2d50b101
Autor:
Anders Foller Füchtbauer, Søren Preus, Karl Börjesson, Scott A. McPhee, David M. J. Lilley, L. Marcus Wilhelmsson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The bright fluorescent cytosine analogue tCO stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA.
Externí odkaz:
https://doaj.org/article/f9924c7b2eb845ad804425dc82e6bff6
Autor:
Željka Ban, Josipa Matić, Biserka Žinić, Anders Foller Füchtbauer, L. Marcus Wilhelmsson, Ivo Piantanida
Publikováno v:
Molecules, Vol 25, Iss 9, p 2188 (2020)
We synthesized a new amino acid-fluorescent nucleobase derivative (qAN1-AA) and from it two new fluorescent nucleobase–fluorophore (pyrene) conjugates, whereby only the analogue with the longer and more flexible linker (qAN1-pyr2) self-folded into
Externí odkaz:
https://doaj.org/article/add424ef1efd4047ae0b0858e38a6332
Autor:
L. Marcus Wilhelmsson, Yii-Lih Lin, Felix Ritort, Uttama Dutta, Fredrik Westerlund, Xavier Viader-Godoy, Vinoth Sundar Rajan
Publikováno v:
Physical Chemistry Chemical Physics
We use mechanical unfolding of single DNA hairpins with modified bases to accurately assess intra- and intermolecular forces in nucleic acids. As expected, the modification stabilizes the hybridized hairpin, but we also observe intriguing stacking in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca827c7a82fa3930459a34afddf647d
http://europepmc.org/articles/PMC8261857
http://europepmc.org/articles/PMC8261857
Autor:
Tom Baladi, Audrey Gallud, Malin Lemurell, L. Marcus Wilhelmsson, Elin K. Esbjörner, Dženita Baždarević, Anders Dahlén, Jesper R. Nilsson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
To expand the antisense oligonucleotide (ASO) fluorescence labeling toolbox beyond covalent conjugation of external dyes (e.g. ATTO-, Alexa Fluor-, or cyanine dyes), we herein explore fluorescent base analogues (FBAs) as a novel approach to endow flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80e09fd2ce1d971e6e5517fd38d1def
https://pubmed.ncbi.nlm.nih.gov/34059711
https://pubmed.ncbi.nlm.nih.gov/34059711