Výsledky vyhledávání - "L. Mangiarini"

Striatal Transplantation in a Transgenic Mouse Model of Huntington's Disease

Autor: A. J. Morton, Gillian P. Bates, Eduardo Miguel Torres, L. Mangiarini, Stephen B. Dunnett, Colin Watts, Rebecca J. Carter, A. Mahal

Publikováno v: Experimental Neurology. 154:31-40

Striatal grafts have been proposed as a potential strategy for striatal repair in Huntington's disease, but it is unknown whether the diseased brain will compromise graft survival. A transgenic mouse line has recently been described in which hemizygo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93d9388d69fc0eaf781f755fc1fb22f
https://doi.org/10.1006/exnr.1998.6926

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Twelfth annual symposia on etiology, pathogenesis, and treatment of parkinson's disease and etiology, pathogenesis, and treatment of Huntington's disease

Autor: S. B. Wilkinson, D. S. Sax, K. Kompoliti, C. Eberly, L. M. Shulman, S. A. Factor, K. K. Zakzanis, M. Brewer, C. DeCarti, M. Takanashi, S. A. Alsdorf, K. Frey, M. R. Kilbourn, C. Comella, G. P. Bates, W. M. Chung, A. S. Menon, C. B. Moskowitz, R. Schwartz, J. M. Bertoni, Tatiana Foroud, John Seibyl, A. Minagar, J. Kieltyka, P. M. Conneally, R. A. Hauser, H. Ellgring, W. J. Weiner, S. W. Davies, R. Pahwa, L. Quinn, M. Freedman, R. Innis, A. Willing, E. Kaplan, N. I. Bohnen, Paul J. Tuite, T. Yanagihara, J. H J Cha, J. Hubble, F. Cardoza, G. Rouleau, L. Mangiarini, E. Aylward, M. Guttman, G. Ulm, A. B. Young, B. Pfeiffer, A. Malik, Juan Sanchez-Ramos, A. S. Frey, J. B. Penney, A. I. Troster, K. Abe, G. Bates, K. Francis, K. E. Lyons, Roger L. Albin, W. C. Koller, C. Kornetsky, M. Seeland, L. Leach, K. A. Frey, M. Baehr, R. A. Koeppe, Karl Kieburtz, David Oakes, G. W. Paulson, E. R. Siemers, Joanne Wojcieszek, L. W. Elmer, T. A. Zesiewicz, Kenneth Marek, D. Strickland, Mark Stacy

Publikováno v: Movement Disorders. 13:858-863

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ec5432e57559fcb153af697083b122b
https://doi.org/10.1002/mds.870130522

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Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice

Autor: I, Gourfinkel-An, K, Parain, A, Hartmann, L, Mangiarini, A, Brice, G, Bates, E C, Hirsch

Publikováno v: Journal of neurochemistry. 86(6)

Huntington's disease is an autosomal dominant disorder with degeneration of medium size striatal neurones. As the disease evolves, other neuronal populations are also progressively affected. A transgenic mouse model of the disease (R6/2) that express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60bf3a514bc102ca9be0c49dd296ad46
https://pubmed.ncbi.nlm.nih.gov/12950446

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Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse

Autor: S J, Tabrizi, J, Workman, P E, Hart, L, Mangiarini, A, Mahal, G, Bates, J M, Cooper, A H, Schapira

Publikováno v: Annals of neurology. 47(1)

Huntington's disease is a progressive neurodegenerative disease caused by an abnormally expanded (36) CAG repeat within the ITI5 gene encoding a widely expressed 349-kd protein, huntingtin. The medium spiny neurons of the caudate preferentially degen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::009d86bfb8119fd2d4e8cd343f113d04
https://pubmed.ncbi.nlm.nih.gov/10632104

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Detection of polyglutamine aggregation in mouse models

Autor: S W, Davies, K, Sathasivam, C, Hobbs, P, Doherty, L, Mangiarini, E, Scherzinger, E E, Wanker, G P, Bates

Publikováno v: Methods in enzymology. 309

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e57570f14585ae48da6ea76ed1ace5b8
https://pubmed.ncbi.nlm.nih.gov/10507055

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Local regression of breast tumors following intramammary ganciclovir administration in double transgenic mice expressing neu oncogene and herpes simplex virus thymidine kinase

Autor: M G, Sacco, L, Mangiarini, A, Villa, P, Macchi, O, Barbieri, M C, Sacchi, E, Monteggia, V, Fasolo, P, Vezzoni, L, Clerici

Publikováno v: Gene therapy. 2(7)

Females from a mouse lineage transgenic for the activated rat neu oncogene under the control of the mouse mammary tumor virus (MMTV) long terminal repeat (LTR) all develop breast tumors with high reproducibility within the first 2-3 months of life. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9e1bbc92cb5b4d07476c58d7fac4af59
https://pubmed.ncbi.nlm.nih.gov/7584128

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Akademický článek

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Akademický článek

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