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pro vyhledávání: '"L. M. Stragovich"'
Autor:
L. M. Stragovich, L. M. Bistrova, N. P. Kuznetsova, Selivanov Ea, L. R. Gudkin, R. N. Mishaeva
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 26:213-222
Polymer aspects of polycondensation of pyridoxylated hemoglobin with glutaraldehyde have been considered. On the basis of the investigation of reaction kinetics, the mechanism of chemical crosslinking of hemoglobin molecules into oligohemoglobin is p
Autor:
V. I. Rugal, Bystrova Im, L.R. Gudkin, G.V. Samsonov, R. N. Mishchaeva, L. M. Stragovich, Selivanov Ea, V. N. Shabalin, I. F. Molokovskaya, Kuznetsova Np
Publikováno v:
Bulletin of Experimental Biology and Medicine. 107:560-563
Publikováno v:
Voprosy meditsinskoi khimii. 34(4)
Oligomeric hemoglobins were produced after polycondensation with glutaric aldehyde (OHb) as well as after modification with pyridoxal-5-phosphate (OHb-PLP). OHb exhibited high affinity to oxygen (P50 = 17 torr) as well as a decreased rate of the subu