Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L. M. Shlapatska"'
Publikováno v:
Biopolymers and Cell. 36:99-109
Publikováno v:
Experimental oncology. 43(4)
SLAMF1/CD150 receptor is aberrantly expressed in malignant hematopoietic cells compared to ubiquitous expression in their normal analogues. However, the data about CD150 expression and function outside the hematopoietic system are limited. The aim of
Publikováno v:
Neoplasma. 68(4)
Chronic lymphocytic leukemia (CLL) is a strikingly heterogeneous disease both at the molecular level and clinical disease course. The malignant B cells obtain key proliferation and survival signals within lymph nodes or bone marrow. Moreover, CLL B c
Publikováno v:
Scopus-Elsevier
Response of chronic lymphocytic leukemia (CLL) patients to classical chemoimmunotherapy that remains the main strategy in treatment of this disease is strikingly variable. This issue requires the finding of biomarkers which could predict efficiency o
Autor:
L. M. Shlapatska, L M Kovalevska, V M Kholodniuk, I M Gordiienko, S. P. Sidorenko, T S Ivanivskaya
Publikováno v:
Scopus-Elsevier
Background: Sequential stages of B-cell development is stringently coordinated by transcription factors (TFs) network that include B-lineage commitment TFs (Ikaros, Runx1/Cbfb, E2A, and FOXO1), B-lineage maintenance TFs (EBF1 and PAX5) and stage spec
Publikováno v:
Scopus-Elsevier
Background: Within B-cell lineage cell surface receptor CD150/SLAMF1 is broadly expressed starting from pre-B cells with upregulation toward plasma cells. However, expression of CD150 is rather limited on the surface of malignant B cells with the blo
Publikováno v:
Clinical Immunology
SLAMF1/CD150 receptor is a founder ofsignaling lymphocyte activation molecule(SLAM) family ofcell-surface receptors. It is widely expressed on cells withinhematopoietic system. Inhematologic malignanciesCD150cell surfaceexpression is restricted to cu
Autor:
Edward A. Clark, Svetlana P. Sidorenko, Valeriia Kholodniuk, D F Gluzman, L. M. Shlapatska, L M Sklyarenko, I M Gordiienko
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185940 (2017)
PLoS ONE
PLoS ONE
Cell surface expression of CD150 and CD180 receptors in chronic lymphocytic leukemia (CLL) associates with mutational IGHV status and favourable prognosis. Here we show a direct correlation between cell surface expression and colocalization of these
Autor:
Maria Y Yurchenko, L. M. Shlapatska, Edward A. Clark, Svetlana P. Sidorenko, Svitlana V. Mikhalap, Ganna G Berdova, Kim E. Nichols, Olga V. Yurchenko
Publikováno v:
Blood. 104:4063-4070
The CD150 receptor is expressed on activated T and B lymphocytes, dendritic cells, and monocytes. A TxYxxV/I motif in the CD150 cytoplasmic tail can bind different SH2-containing molecules, including tyrosine and inositol phosphatases, Src family kin
Autor:
Mariya Yurchenko, L. M. Shlapatska, Edward A. Clark, Ganna G Berdova, Svetlana P. Sidorenko, L M Kovalevska
Publikováno v:
Immunology and cell biology. 88(5)
The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with