Zobrazeno 1 - 10
of 102
pro vyhledávání: '"L. M. Potikha"'
Publikováno v:
Russian Journal of General Chemistry. 92:174-184
Abstract A method for the synthesis of 5-phenyl-1,3-thiazole-4-sulfonyl chloride was developed based on the cyclization of ethyl 2-{[1-(benzylsulfanyl)-2-oxo-2-phenylethyl]amino}-2-oxoacetate obtained from available reagents under the action of the L
Autor:
L. M. Potikha, Volodymyr Brovarets
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1460-1464
2-Aryl-2-(2-aryl-2-oxoethyl)-1H,2H,3H-imidazo[1,2-a]pyridin-4-ium bromides were obtained in the reaction of (2Z)-4-bromo-1,3-diphenylbut-2-en-1-one derivatives with 2-aminopyridines in benzene. The effect of the structure of the starting reagents on
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1454-1459
A novel method for the synthesis of pyrido[1,2-b][2]benzazepine derivatives is based on the reaction of 2-(bromomethyl)benzophenones and 2-(bromomethyl)benzaldehyde with 2-methylpyridines. The route of synthesis of 6H-pyrido[1,2-b][2]benzazepinium sa
Synthesis of imidazo[2,1-b][1,3]thiazoles – potential anticancer agents derived from γ-bromodipnones
Autor:
Volodymyr Brovarets, L. M. Potikha
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1073-1077
We propose a new method for assembling the imidazo[2,1-b][1,3]thiazole system, based on the reaction of (2Z)-1,3-diaryl-4-bromobut-2-en-1-one derivatives with 2-aminothiazoles. The outcome of this reaction depends on the structure of the starting bro
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:367-373
Quaternization of 4-amino-4H-1,2,4-triazole with γ-bromodipnones and 5-(bromomethyl)-2,2,6,6-tetramethylhept-4-en-3-one occurred at the N-1 nitrogen atom, with the formation of quaternary salts that were cyclized in the presence of bases into [1,2,4
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:416-420
A number of 1,4-benzoxathiine derivatives was obtained using ring contraction of seven-membered cycle of 3,4-dihydro-2H-1,5-benzoxathiepin-3-ol derivatives. This synthetic approach allowed to obtain the corresponding alkene, alcohol, nitrile, chlorid
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 14:61-66
Піперідини, спіросполучені з іншими гетероциклами як структурні елементи фармакологічно активних лейовані фраґменти» лігандів метабо
Autor:
Volodymyr O. Kovtunenko, L. M. Potikha, Oleg V. Shishkin, Andriy V. Shelepyuk, Roman I. Zubatyuk
Publikováno v:
Journal of Heterocyclic Chemistry. 52:539-544
A new method based on reaction of 4-bromobut-2-enoates with N-alkylimidazoles was proposed for obtaining 1R-1H-imidazo[1,2-a]pyridin-4-ium-8-olate and 1-R-8-methoxy-1H-imidazo[1,2-a]pyridin-4-ium derivatives. The structures of synthesized compounds w
Publikováno v:
Chemistry of Heterocyclic Compounds. 49:294-301
A new method is proposed for the preparation of 1-hydroxypyrido[1,2-b]isoquinolinium bromides by intramolecular aromatic electrophilic substitution in 3-hydroxy-1-(2-formylbenzyl)pyridinium, 3-hydroxy- and 3-amino-1-[2-(4-chlorobenzoyl)benzyl]pyridin
Autor:
Vladimir A. Kovtunenko, L. M. Potikha, Oleg V. Shishkin, V. V. Sypchenko, Vyacheslav N. Baumer
Publikováno v:
Chemistry of Heterocyclic Compounds. 48:1033-1042
A new method is proposed for the preparation of N-(2-aminophenyl)isoindoles by the reaction of o-(bromomethyl)benzophenones with 1,2-phenylenediamines. The reaction of N-(2-aminophenyl)isoindoles with Ac2O leads to 1,N-diacetyl- or 1,N,N-triacetyl de