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pro vyhledávání: '"L. M. O'Keeffe"'
Publikováno v:
British Journal of Cancer
The parathyroid hormone-related protein (PTHrP) gene consists of nine exons and allows the production of multiple PTHrP mRNA species via the use of three promoters and 5' and 3' alternative splicing; as a result of 3' alternative splicing one of thre
Autor:
J Southby, Takeshi Kiriyama, Jane M. Moseley, Matthew T. Gillespie, L M O'Keeffe, Joan K. Heath, Thomas J. Martin, Jane A. Glatz
Publikováno v:
Molecular and cellular endocrinology. 101(1-2)
Dexamethasone regulation of PTHrP expression has been studied in an epidermal squamous cancer cell line COLO 16, which secretes immunoreactive PTHrP into conditioned medium. Dexamethasone was found to suppress PTHrP expression in a time- and dose-dep