Zobrazeno 1 - 10
of 28
pro vyhledávání: '"L. M. Makarenkova"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 2, Pp 112-118 (2021)
Introduction. Gestobutanoil is a synthetic pregnane steroid with gestagenic activity. Gestobutanoil has two pharmacologically active metabolites (AMOL and megestrol acetate). This implies the need for a detailed study of the kinetics of metabolites.
Externí odkaz:
https://doaj.org/article/574fc97ef87e4f80b8fd5ba0af23cc47
Autor:
S. K. Zyryanov, L. M. Makarenkova, V. V. Chistyakov, A. M. Kazanova, E. S. Stepanova, S. P. Senchenko
Publikováno v:
Pharmaceutical Chemistry Journal. 54:414-418
The development of an HPLC method for quantitative determination of meropenem in human blood plasma for therapeutic drug monitoring in clinics is reported. Spectrophotometric detection was made at 298 nm. The chromatography time was 12 min. The metho
Autor:
L. M. Makarenkova, E. S. Stepanova, P. O. Bochkov, A. V. Kozlov, V. V. Chistyakov, Dmitriy A. Sychev, V. V. Smirnov
Publikováno v:
Pharmaceutical Chemistry Journal. 53:771-774
Two different literature methods were used to compare the experimental efficacy and accuracy of dabigatran assays in blood of 30 patients with knee replacements. Blood plasma was collected from patients who underwent anticoagulant therapy and were ad
Autor:
V. A. Votyakov, E. S. Stepanova, V. A. Parshin, N. L. Shimanovskii, Yu. L. Rybakov, T. A. Fedotcheva, V. M. Gukasov, L. M. Makarenkova, V. V. Chistyakov
Publikováno v:
Pharmaceutical Chemistry Journal. 52:1016-1020
An HPLC-MS method for simultaneous quantitative determination of a novel gestagenic pharmaceutical and two of its metabolites in rat and rabbit blood sera was developed and validated. The method was selective and specific. The detection limit for all
Publikováno v:
Pharmaceutical Chemistry Journal. 52:248-253
An HPLC-MS/MS method for quantitative determination of the new antituberculosis drug PBTZ169 in blood serum, urine, and feces using perindopril as an internal standard was developed and validated. The method was selective, specific, accurate, and pre
Autor:
T. A. Fedotcheva, N. L. Shimanovsky, E. S. Stepanova, L. M. Makarenkova, V. V. Chistyakov, V. A. Parshin
Publikováno v:
Sovremennye tehnologii v medicine. 11:48
Autor:
Igor V. Bliznets, L. M. Makarenkova, Vladimir A. Tartakovsky, Sema L. Ioffe, Yu. A. Strelenko
Publikováno v:
Russian Chemical Bulletin. 49:1261-1269
The reactions of primary amines withN,N-bis(trimethylsilyloxy) enamines can give products of both mono-and bis-α-oximinoalkylation of primary amines. The steric restrictions in both reactants substantially retard bis-α-oximinoalkylation. A general
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 29
Publikováno v:
ChemInform. 30