Zobrazeno 1 - 6
of 6
pro vyhledávání: '"L. M. Karnitz"'
Autor:
Michael J. Quon, L. M. Karnitz, Robert V. Farese, Mary L. Standaert, Gautam Bandyopadhyay, Li-Na Cong, Mini P. Sajan
Publikováno v:
Molecular Endocrinology. 13:1766-1772
Previous studies have suggested that 1) atypical protein kinase C (PKC) isoforms are required for insulin stimulation of glucose transport, and 2) 3-phosphoinositide-dependent protein kinase-1 (PDK-1) is required for activation of atypical PKCs. Pres
Publikováno v:
Cancer research. 60(13)
The microbially derived antiproliferative agent rapamycin inhibits cell growth by interfering with the signaling functions of the mammalian target of rapamycin (mTOR). In this study, we demonstrate that interleukin-3 stimulation induces a wortmannin-
Publikováno v:
Cancer research. 60(8)
The investigational anticancer agent 7-hydroxystaurosporine (UCN-01) abrogates the G2 checkpoint in tumor cells and sensitizes them to the lethal effects of genotoxic anticancer agents. On the basis of the role of the Cdc25C phosphatase in maintenanc
Autor:
L M, Karnitz, R T, Abraham
Publikováno v:
Advances in immunology. 61
Publikováno v:
Advances in experimental medicine and biology. 365
Publikováno v:
The Journal of biological chemistry. 268(24)
Stimulation of activated T cells with interleukin-2 (IL-2) results in the tyrosine phosphorylation of several intracellular proteins. The present studies demonstrate that IL-2 stimulation induces phosphorylation of the src homology 2 domain-containin