Dose-response relationship of dexrazoxane for prevention of doxorubicin-induced cardiotoxicity in mice, rats, and dogs

Autor: A R, Imondi, P, Della Torre, G, Mazué, T M, Sullivan, T L, Robbins, L M, Hagerman, A, Podestà, G, Pinciroli

Publikováno v: Cancer research. 56(18)

Dexrazoxane [(DZR), ADR 529, ICRF-187] ameliorates doxorubicin (DOX)-induced cardiotoxicity in animals, and is recommended as a cardioprotectant in patients receiving cumulative doses of DOX above 300 mg/m2. A DZR:DOX dose ratio of 10:1 is recommende

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d21669e8b9bbe2bb785b4753b84a7fc3
https://pubmed.ncbi.nlm.nih.gov/8797592

Bioavailability of 14C-sulpiride in dogs

Autor: A S, Alam, A R, Imondi, J, Udinsky, L M, Hagerman

Publikováno v: Archives internationales de pharmacodynamie et de therapie. 242(1)

The plasma and urinary concentrations of unchanged 14C-sulpiride were measured in the dog following i.v. and oral administration. Bioavailability of the oral hydrochloride solution was 85% and that of the free base suspension was 75%. Sulpiride equil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dcc2c52f3fc74b22c0605f2df37a6e7c
https://pubmed.ncbi.nlm.nih.gov/543747

Toxicity and Tissue Distribution of MVE-2 in the Dog After Intravenous and Intraperitonal Administration

Autor: R. A. Carrano, L. M. Hagerman, J. D. Iuliucci, J. R. Baldwin, A. R. Imondi

Publikováno v: Polymeric Materials in Medication ISBN: 9781489922472

The maleic anhydride: divinyl ether (MVE-2) used in this study is a water soluble anionic polymer with a mean molecular weight of 11, 000. The demonstration in laboratory animals of immunologic and antitumor properties by this polymer has led to its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f16bee312327adc62d3f3a1bac1679b8
https://doi.org/10.1007/978-1-4899-2245-8_12

Abstracts of Submitted Papers

Autor: E. Baraona, R. Pirola, C. S. Lieber, J. W. Barnhart, J. D. Johnson, D. J. Rytter, R. B. Failey, R. Beckmann, G. Hillmann, F. Lagler, W. Linlz, W. Vollenberg, Donald Berkowitz, Arthur Bernstein, Franklin Simon, William Warner, A. Bizzi, A. M. Codegoni, A. Medea, S. Garattini, S. Bjorkerud, G. Bondjers, J. Boberg, L. A. Carlson, U. Freyschuss, B. Lassers, M. Wahlqvist, A. G. Olsson, S. Froberg, L. Oro, S. Rossner, G. Walldius, R. W. Butcher, Virgilio Bosch, Halina C. Mendez, German Camejo, H. B. Brewer, R. Shulman, P. Herbert, R. Ronan, K. Wehrly, D. Brunner, S. Altman, K. Loebl, M. Burstein, H. R. Scholnick, H. Richard Casdorph, Robert Ausman, Thomas H. Schmitz, M. N. Cayen, D. Dvornik, W. E. Connor, A. Wartman, D. Wittiak, G. Crepaldi, D. Fedele, R. Fellin, G. Bagnariol, G. Briani, Colin Dalton, Herbert Sheppard, J. L. de Gennes, G. Turpin, J. Truffert, Mary E. Dempsey, Mary C. Ritter, Donald T. Witiak, H. Ditschuneit, H. H. Ditschuneit, H. U. Klor, D. Rakow, P. Schwandt, P. Dorigo, G. Fassina, Gregory S. Duboff, Charles H. Eades, E. Schwartz, D. Abrutyn, K. David, G. Edwards, Margaret R. Hawkins, C. D. Eskelson, L. A. Meeks, R. G. Lamb, L. L. Adams, H. J. Fallon, Elaine B. Feldman, Charles Y. Cheng, Dolores H. Henderson, H. Frost, P. Heimstadt, Arlene S. Garfinkel, Michael C. Schotz, E. Stewart, V. V. Glaviano, T. N. Masters, Charles J. Glueck, Martin Gold, Henry Altschuler, A. Woldow, Y. Goto, Y. Nakamura, E. Asano, H. Nakamura, H. Greten, H. Wengeler, D. Seidel, H. Wieland, F. A. Gries, H. D. Miss, H. Canzler, T. Koschinsky, K. H. Vogelberg, K. Jahnke, Kare Gundersen, F. P. Kupiecki, Georges Hartmann, P. Hill, J. F. Douglas, A. N. Howard, D. E. Hyams, S. K. Hsia, James E. Fulton, Karl Huth, Arnold Kaplan, Masao Kariya, Takashi Kariya, Thomas R. Blohm, J. Martin Grisar, Roger A. Parker, Jeanne R. Martin, S. L. Katyal, J. Saha, J. J. Kabara, A. N. Klimov, O. K. Dokusova, L. A. Petrova, E. D. Poliakova, T. A. Klimova, B. J. Kudchodkar, L. Horlick, H. S. Sodhi, D. J. Nazir, Peter T. Kuo, H. Lengsfeld, H. Gallo-Torres, V. V. Lyachovich, I. B. Tsyrlcv, V. M. Mishin, O. A. Gromova, Hans J. Meyer, M. A. Mishkel, L. M. Morrison, O. A. Schjeide, G. S. Bajwa, B. H. Ershoff, C. D. Moutafis, N. B. Myant, David T. Nash, D. M. Ottenstein, W. R. Supina, D. A. Bartley, Nicholas Pelick, William R. Owen, E. Panak, J. Daver, M. Podesta, E. Edmond, J. Papenberg, G. Schlierf, H. Peeters, V. Blaton, B. Declercq, D. Vandamme, Joseph N. Pereira, Gerald A. Mears, Gerald F. Holland, A. A. Polachek, H. M. Katz, M. Littman, N. S. Radin, R. C. Arora, A. Lazzarini Robertson, R. Sanwald, H. Wagener, Terence J. Scallen, H. B. Skrdlant, M. V. Srikantaiah, Robert Scheig, Guenter Schlierf, Eckehard Dorow, D. L. Schneider, L. M. Hagerman, P. Segal, P. S. Roheim, H. A. Eder, David J. Shapiro, Victor W. Rodwell, Charles M. Siegfried, William H. Elliott, M. C. Stone, T. B. S. Dick, M. T. Ravi Subbiah, Bruce A. Kottke, William J. Martin, Kay Tanaka, Kurt J. Isselbacher, G. R. Thompson, J. D. Cameron, T. J. Peters, C. N. C. Drey, K. Toki, H. Nakatani, E. G. Tombropoulos, A. S. Truswell, G. Watermeyer, J. I. Mann, M. Vavrecka, Joseph F. Weiss, Joseph Ransohoff, Herbert J. Kayden, A. Weizel, Lawrence W. White, J. P. D. Wilson, D. J. Galton, Akira Yamamoto, Susumu Adachi, Katsunori Ishikawa, Teruo Kitani, Terushi Nasu, Yoshitake Shinji, Ko-Ichi Seki, Mitsuo Nishikawa, Nepomuk Zollner, Gunther Wolfram

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781468475494

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9314dd22fbbd922da876e2fee24b652
https://doi.org/10.1007/978-1-4684-7547-0_24

Effect of cholestyramine particle size on in vitro binding of conjugated bile salts

Autor: D. A. Cook, D. L. Schneider, L. M. Hagerman

Publikováno v: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 139(1)

SummaryCholestyramine (50-75 μ in diameter) was incubated with graded levels of taurocholate, glycocholate, taurodeoxycholate, or glycodeoxycholate in 0.3 M phosphate buffer. The resin showed a preference for taurine conjugates over glycine conjugat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83fcbebdccf0d56517fbea264c27f7c
https://pubmed.ncbi.nlm.nih.gov/5061706