Different Effects of an Oral Anticholinergic Drug on Gastroesophageal Reflux in Upright and Supine Position in Normal, Ambulant Subjects: A Pilot Study

Autor: David A. Katzka, K. G. Pursnani, M. A. Mohiuddin, Paolo L. Peghini, L. M. A. Akkermans, J. Koerselman, D. O. Castell

Publikováno v: American Journal of Gastroenterology. 94:925-930

There is controversy in the literature on the effects of anticholinergic drugs on gastroesophageal reflux. Our aim was to study more extensively the effects of an oral anticholinergic drug on esophageal motility and gastroesophageal reflux in normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdb7b5ba5e6e345da4d65a76fdcef4e
https://doi.org/10.1111/j.1572-0241.1999.988_k.x

Biofeedback training in treatment of childhood constipation: a randomised controlled study

Autor: R N van der Plas, Marc A. Benninga, Hans A. Büller, L. M. A. Akkermans, Patrick M.M. Bossuyt, William K. Redekop, Jan A.J.M. Taminiau

Publikováno v: Lancet, 348(9030), 776-780. Elsevier Limited

BACKGROUND: Because abnormal defaecation dynamics, which can be modified by biofeedback, are considered to be the underlying problem in constipation, biofeedback training may be a useful treatment for constipation. This treatment has mainly been stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ffc4d4e79bb663635ab1a4126e1bf2
https://doi.org/10.1016/s0140-6736(96)03206-0

Abstracts of papers Pharmacological Meeting

Autor: W. A. Bax, P. R. Saxena, Gerreke Ph. Biewenga, Jan Jong, Aalt Bast, Pauline G. M. Bloemen, Maria C. Tweel, Paul A. J. Henricks, Ferdi Engels, Frans P. Nijkamp, H. E. Molewijk, A. M. Poel, B. Olivier, M. R. Briejer, J. A. J. Schuurkes, L. M. A. Akkermans, T. A. Bruning, M. G. C. Hendriks, P. C. Chang, E. A. P. Kuypers, P. A. Zwieten, S. L. T. Cappendijk, R. Vries, M. R. Dzoljic, J. A. Bouwknecht, F. R. L. Crijns, M. S. P. Huijberts, H. A. J. Struijker Boudier, A. C. Nieuwenhuijzen Kruzeman, B. H. R. Wolffenbuttel, L. M. Lannov, A. H. J. Danser, R. G. Schoemakef, M. A. D. H. Schalekamp, Xiao Y. Du, Regien G. Schoemaker, Pramod R. Saxena, E. A. Dubois, H. D. Batink, M. Pfaffendorf, E. A. Roven, I. M. Garrelds, C. Graaf-in 't Veld, F. J. Ziilstra, A. P. H. Jansen, R. Gerth Wijk, B. C. G. Gho, R. G. Schoemaker, C. v. d. Lee, H. S. Sharma, P. D. Verdouw, L. Groenink, J. Gugten, T. J. J. Zethof, P. Hasselaar, J. W. C. M. Jansen, J. J. J. Giezen, G. H. Dreteler, A. Hulkenberq, J. H. Reinders, G. P. Toorop, A. H. J. Herremans, T. H. Hijzen, J. L. Slangen, E. M. Hessel, A. J. M. Oosterhout, C. Hofstra, J. Garssen, H. Loveren, H. F. J. Savelkoul, F. P. Nijkamp, Thorwald Hol, Jan M. Ree, Berry M. Spruijt, B. C. P. Hüsken, P. A. Zwieren, E. A. J. Kalkman, K. L. Kam, C. W. Keuzenkamp-Jansen, R. A. Abreu, J. P. M. Bökkerink, M. A. H. Heijden, J. M. F. Trijbels, A. D. Kraneveld, T. L. Buckley, Y. Schaik, A. Sj. Koster, R. A. A. Mathôt, B. C. F. M. Aarsen, M. W. E. Langemeijer, A. P. Ijzerman, M. Danhof, Inqe C. M. Mohede, Antoon J. M. Oosterhout, M. Monshouwer, R. F. Witkamp, S. M. Nijmeijer, A. S. J. P. A. M. Miert, J. Oosting, B. J. A. Janssen, A. J. Pijl, A. C. Wal, M. -J. Mathy, W. M. Pruimboom, A. P. M. Dijk, C. J. A. M. Tak, I. L. Bonta, J. H. P. Wilson, D. J. Bac, F. J. Zijlstra, G. Sadeghi Hashjin, G. Folkerts, P. A. J. Henricks, R. E. Santing, Y. Pasman, C. G. Olymulder, A. F. Roffel, J. Zaaqsma, H. Meurs, Heleen Scheerens, Theresa L. Buckley, Henk Loveren, H. Sipma, M. Duin, A. Hertog, A. Nelemans, J. Smit, R. P. Coppes, A. Geurtsen, J. Zaagsma, M. J. Smit, R. Leurs, A. Bast, H. Timmerman, F. R. M. Stassen, J. G. R. Mey, R. E. J. Berge, Guno H. K. Tjon, Taco J. Vries, Eric Ronken, François Hogenboom, George Warden, Arie H. Mulder, Anton N. M. Schoffelmeer, P. Bergen, J. A. Kleline, P. M. L. Janssen, J. G. M. Vaart, C. M. Kasbergen, D. H. G. Versteeg, D. J. Wildt, M. J. Velde, F. Engels, C. Berg, W. Vleeming, J. G. C. Amsterdam, J. Werner, L. Zee, A. Hertoe, E. Marcel Gelderen, Hendrik J. Agteresch, Emile L. E. Bruijne, J. P. Kats, L. M. A. Sassen, P. J. J. Admiraal, P. P. Verdouw, F. L. Muiswinkel, H. W. M. Steinhusch, B. Drukarch, J. C. Sloof, J. Vente, L. J. M. J. Vanderschuren, J. M. Ree, P. Verkade, A. J. Verkleij, W. H. Gispen, A. B. Oestreicher, R. J. Vermeulen, C. Goosen, E. Ch. Wolters, J. C. Stoof, V. A. M. Vincent, A. N. M. Schoffelmeer, H. W. M. Steinbush, F. Berlcenbosch, Hans-Peter Voss, David Donnell, J. P. M. Wesselman, E. VanBavel, J. A. E. Spaan, W. M. Zeilmaker, G. A. E. Klooster, G. J. M. J. Horbach, J. Zhang, J. S. Zhang, J. C. A. Meet

Publikováno v: Pharmacy World & Science. 15:I1-I15

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::511b401ccdbc6812b8ebdac72f4febd4
https://doi.org/10.1007/bf01875421

Trypsinogen IV, serotonin transporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients

Autor: J. J. M. Ter Linde, M. Samsom, A. P. M. Kerckhoffs, L. M. A. Akkermans

Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 20(8)

Colorectal and small intestinal visceral hypersensitivity has been demonstrated in irritable bowel syndrome (IBS). Serine protease signalling via protease-activated receptor (PAR)-2 promotes hyperalgesia to mechanical distension. Furthermore, seroton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99af30e7e6e1a159701fe9c4944d2be4
https://pubmed.ncbi.nlm.nih.gov/18363639

A new intelligent distension system for hollow organs

Autor: L. M. A. Akkermans, Alfred Bayati, Martin Karpefors

Publikováno v: Medicalbiological engineeringcomputing. 45(3)

Controlled distension of hollow organs is an accepted technique for generating reproducible visceral stimuli. We have constructed a new, flexible and intelligent distension system in which discomfort, pain and autonomic responses are recorded online.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e51e7490bcaf81f89b437cd5b9383ff
https://pubmed.ncbi.nlm.nih.gov/17221257