Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L. Lynn McGrew"'
Publikováno v:
Development, Growth and Differentiation. 42:347-357
In spite of abundant evidence that Wnts play essential roles in embryonic induction and patterning, little is known about the expression or activities of Wnt receptors during embryogenesis. The isolation and expression of two maternal Xenopus frizzle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcbe9bd079a907c3d966f415b45f666
https://doi.org/10.1046/j.1440-169x.2000.00517.x
https://doi.org/10.1046/j.1440-169x.2000.00517.x
Autor:
Randall T. Moon, Susan M. Purcell, Monica Torres, Julia A. Yang-Snyder, Alyce A. DeMarais, L. Lynn McGrew
Publikováno v:
The Journal of Cell Biology
When overexpressed in Xenopus embryos, Xwnt-1, -3A, -8 and -8b define a functional class of Wnts (the Wnt-1 class) that promotes duplication of the embryonic axis, whereas Xwnt-5A, -4, and -11 define a distinct class (the Wnt-5A class) that alters mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd39b8481569d8ce473d658242ea8a8
http://europepmc.org/articles/PMC2120849
http://europepmc.org/articles/PMC2120849
Autor:
D.P. von Kessler, Philip A. Beachy, Stephen C. Ekker, Jiae Lee, Randall T. Moon, L. Lynn McGrew, Cheng-Jung Lai
Publikováno v:
Development. 121:2337-2347
The hedgehog family of signaling proteins is associated with a variety of spatial patterning activities in insects and vertebrates. Here we show that new members of this family isolated from Xenopus laevis are expressed embryonically in patterns sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755dc3b000c60572e05fa865a3360445
https://doi.org/10.1242/dev.121.8.2337
https://doi.org/10.1242/dev.121.8.2337
Autor:
Cheng-Jung Lai, Robert M. Campbell, Jan L. Christian, Gregory M. Kelly, Randall T. Moon, Daniel J. Olson, L. Lynn McGrew, Monica Torres, Alyce A. DeMarais
Publikováno v:
Development. 119:85-94
We review evidence that Xenopus Wnts (Xwnts) have activities consistent with their hypothesized roles as secreted signalling factors involved in multiple developmental processes. Transient misexpression of different Xwnts has distinct effects upon ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a201e164cdb5665799145bbc01ce0697
https://doi.org/10.1242/dev.119.supplement.85
https://doi.org/10.1242/dev.119.supplement.85
Autor:
Jan L. Christian, Robert M. Campbell, John Shih, Randall T. Moon, Scott E. Fraser, L. Lynn McGrew
Publikováno v:
Development. 119:97-111
To contribute to an understanding of the roles and mechanisms of action of Wnts in early vertebrate development, we have characterized the normal expression of Xenopus laevis Wnt-5A, and investigated the consequences of misexpression of this putative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d94e25adfb9cf64d3f90ff72f8af35d
https://doi.org/10.1242/dev.119.1.97
https://doi.org/10.1242/dev.119.1.97
Publikováno v:
Development. 116:141-146
During early embryonic development, many inductive interactions between tissues depend on signal transduction processes. We began to test the possibility that G-proteins participate in the signal transduction pathways that mediate neural induction. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990d91d33594830b31157552f14fcef2
https://doi.org/10.1242/dev.116.1.141
https://doi.org/10.1242/dev.116.1.141
Publikováno v:
Development. 115:463-473
This study characterizes the temporal and spatial expression during early Xenopus development of Xwnt-4, a member of the Wnt gene family. The Xwnt-4 protein contains all of the sequence motifs that are hallmarks of the Wnt gene family and is 84% iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9f07b21180cd833391c1b5e1eb7080
https://doi.org/10.1242/dev.115.2.463
https://doi.org/10.1242/dev.115.2.463
Publikováno v:
Mechanisms of development. 87(1-2)
The co-activation of Wnt signaling and concomitant inhibition of BMP signaling has previously been implicated in vertebrate neural patterning, as evidenced by the combinatorial induction of engrailed-2 and krox-20 in Xenopus . However, screens have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14b9772fedff7a2f031028eb1ee61b3
https://pubmed.ncbi.nlm.nih.gov/10495268
https://pubmed.ncbi.nlm.nih.gov/10495268
Publikováno v:
Mechanisms of development. 69(1-2)
Previous gain-of-function assays in Xenopus have demonstrated that Xwnt-3a can pattern neural tissue by reducing the expression of anterior neural genes, and elevating the expression of posterior neural genes. To date, no loss-of-function studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731962b29b0879b94598880dd03e54e4
https://pubmed.ncbi.nlm.nih.gov/9486534
https://pubmed.ncbi.nlm.nih.gov/9486534
Publikováno v:
Developmental biology. 172(1)
Embryological data and the activities of the neural-inducing factors noggin and follistatin are consistent with the hypothesis that the nervous system is initially induced with an anterior character, with subsequent signals imparting posterior patter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2f0a792fc528e65be98e9cd2cd3414
https://pubmed.ncbi.nlm.nih.gov/7589812
https://pubmed.ncbi.nlm.nih.gov/7589812