Zobrazeno 1 - 10
of 74
pro vyhledávání: '"L. Lyndon Key"'
Autor:
William L. Ries, L. Lyndon Key, Sakamuri V. Reddy, Srinivasan Shanmugarajan, C Musselwhite, K Irie
Publikováno v:
The Journal of Pathology. 213:420-428
Regulatory mechanisms operative in bone-resorbing osteoclasts are complex. We previously defined the Ly-6 gene family member OIP-1/hSca as an inhibitor of osteoclastogenesis in vitro; however, a role in skeletal development is unknown. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6e74930c76fa63434d612655d177b8
https://doi.org/10.1002/path.2241
https://doi.org/10.1002/path.2241
Publikováno v:
The Journal of Neuroscience. 23:7470-7478
In rat glial cells the lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) gene expression was enhanced by extracellular glucose concentration in a dose-dependent manner. On the other hand, 2-deoxy-d-glucose decreased the LPS-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d09571a99a13d9fda56a2eae462e1eb
https://doi.org/10.1523/jneurosci.23-20-07470.2003
https://doi.org/10.1523/jneurosci.23-20-07470.2003
Autor:
Fumihiko Ishikawa, Christopher J. Drake, Su Yang, Paul A. Fleming, W. Scott Argraves, Mine Harada, Anne G. Livingston, Makio Ogawa, Hitoshi Minamiguchi, John R. Wingard, L. Lyndon Key, Richard P. Visconti, Christopher V. Crosby
Publikováno v:
Annals of the New York Academy of Sciences. 996:174-185
Recent studies suggest that rodent hepatocytes may be derived from hematopoietic stem cells. In the current study, the potential hematopoietic origin of hepatocytes was addressed using xenogeneic transplantation of human cord blood cells. CD34(+) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644de8952f417b9e84f1708ae943df60
https://doi.org/10.1111/j.1749-6632.2003.tb03245.x
https://doi.org/10.1111/j.1749-6632.2003.tb03245.x
Publikováno v:
Journal of Cellular Biochemistry. 84:645-654
Osteoclasts are the primary cells responsible for bone resorption. Osteoclast formation and bone resorption activities involve processes tightly controlled by a network of cytokines. The presence of interferon gamma (IFN-gamma) receptors on osteoclas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e1f569d422509975dd7163ea13c56d3
https://doi.org/10.1002/jcb.10074
https://doi.org/10.1002/jcb.10074
Publikováno v:
Journal of Interferon & Cytokine Research. 20:645-652
Interferon-gamma (IFN-gamma) treatment increases osteoclastic bone resorption in vivo in patients with malignant osteopetrosis (OP). The treatment effect was studied in vitro in osteoclasts generated by culturing peripheral white blood cells (PWBC) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be93b48f9aa763653e703a201efff6f8
https://doi.org/10.1089/107999000414826
https://doi.org/10.1089/107999000414826
Autor:
Renée Betros, Jeffery R. Craver, Joel K. Curé, Mushfiquddin Khan, G. Shashidhar Pai, Ernest Barbosa, L. Lyndon Key, Inderjit Singh
Publikováno v:
Molecular Genetics and Metabolism. 69:312-322
X-linked adrenoleukodystrophy (X-ALD) is a progressive demyelinating disorder whose neurological signs and symptoms can manifest in childhood as cerebral ALD or in adulthood in the form of a progressive myelopathy (AMN). The consistent metabolic abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7b4a2bf60fb55983dba39a9429e399
https://doi.org/10.1006/mgme.2000.2977
https://doi.org/10.1006/mgme.2000.2977
Publikováno v:
Molecular and Cellular Biochemistry. 199:15-24
Severe, malignant osteopetrosis is a disease characterized by osteoclasts that fail to resorb bone. Serious defects in the ability of white blood cells to eradicate infectious agents confound the clinical course. Defective superoxide generation by ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698940d7cbf00d6d2a03e697026dc562
https://doi.org/10.1023/a:1006990730115
https://doi.org/10.1023/a:1006990730115
Publikováno v:
The Endocrinologist. 8:409-417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1cebd95c4286729be3ee276fdd2d61e
https://doi.org/10.1097/00019616-199811000-00004
https://doi.org/10.1097/00019616-199811000-00004
Publikováno v:
Journal of Urology. 157:1884-1888
Purpose: We determined the incidence of defects in 3 enzymes, namely 3 beta-hydroxysteroid dehydrogenase, 17 alpha-hydroxylase and 17,20-lyase, on the testosterone biosynthetic pathway in boys with hypospadias.Materials and Methods: We evaluated 30 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f946f414a41a453740f05a852167f6
https://doi.org/10.1016/s0022-5347(01)64893-6
https://doi.org/10.1016/s0022-5347(01)64893-6
Publikováno v:
American Journal of Hematology. 53:196-200
A 16-month-old boy, diagnosed at age 3 months with osteopetrosis, was treated since age 6 months with rhlFN-γ in combination with rhM-CSF. The child developed acute respiratory distress within 1 hr of a paternal platelet transfusion. Both the child
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e517f3cf797eb9c0b19d9c7e5afecb9e
https://doi.org/10.1002/(sici)1096-8652(199611)53:3<196::aid-ajh9>3.0.co
https://doi.org/10.1002/(sici)1096-8652(199611)53:3<196::aid-ajh9>3.0.co