Zobrazeno 1 - 10
of 43
pro vyhledávání: '"L. Louters"'
Autor:
M.M. Schreuder, S. Hamkour, K.E. Siegers, K.B. Holven, A.K. Johansen, M.A. van de Ree, B. Imholz, E. Boersma, L. Louters, M.P. Bogsrud, K. Retterstøl, F.L.J. Visseren, J.E. Roeters van Lennep, C. Koopal
Publikováno v:
Atherosclerosis. Elsevier Ireland Ltd
Background and aims: Despite lipid lowering therapy (LLT), reaching LDL-C targets in patients with familial hypercholesterolemia (FH) remains challenging. Our aim was to determine attainment of LDL-C target levels and reasons for not reaching these i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea03dc333c6419a3d0a0958ceeb0131e
https://pure.eur.nl/en/publications/c168c198-4aae-4d40-8259-a34b95070870
https://pure.eur.nl/en/publications/c168c198-4aae-4d40-8259-a34b95070870
Autor:
Miranda F. Bouwer, Larry L. Louters, Brendan D. Looyenga, Kathryn E. Hamilton, Patrick B. Jonker, Sam R. Kuiper
Publikováno v:
Biochimie
Small-molecule inhibitors of enzyme function are critical tools for the study of cell biological processes and for treatment of human disease. Identifying inhibitors with suitable specificity and selectivity for single enzymes, however, remains a cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3925ca087e84bb65bfd0595c9f99e0
https://doi.org/10.1016/j.biochi.2021.03.004
https://doi.org/10.1016/j.biochi.2021.03.004
Autor:
Brendan D. Looyenga, Larry L. Louters, Evans K Lodge, Emily M. Roloff, Jedediah D. Bell, Kathryn E. Hamilton
Publikováno v:
Biochimie
The facilitative glucose transport GLUT1 (SLC2A1) is a constitutively expressed membrane protein involved in basal uptake of blood glucose. GLUT1 modification by N-linked glycosylation at a single asparagine residue (N45) appears to play multiple rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8055a278746e594160ad8fc00d64f597
https://doi.org/10.1016/j.biochi.2020.04.001
https://doi.org/10.1016/j.biochi.2020.04.001
Publikováno v:
Biochimie
The classical methods for determining glucose uptake rates in living cells involve the use of isotopically labeled 2-deoxy- d -glucose or 3-O-methyl- d -glucose, which enter cells via well-characterized membrane transporters of the SLC2A and SLC5A fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582d6542aa6588d311bd46dfada8cb9d
https://europepmc.org/articles/PMC8546778/
https://europepmc.org/articles/PMC8546778/
Publikováno v:
Biochimie. 162:88-96
Glucose is a preferred metabolite in most mammalian cells, and proper regulation of uptake is critical for organism homeostasis. The glucose transporter 1 (GLUT1) is responsible for glucose uptake in a wide variety of cells and appears to be regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4f84ff07663ef8997b2eefd3415a55
https://doi.org/10.1016/j.biochi.2019.04.010
https://doi.org/10.1016/j.biochi.2019.04.010
Akademický článek
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Autor:
Nathan Stehouwer, Brianna M. Busscher, Kathryn E. Hamilton, Jordan L. Scott, Leesha K. Gunnink, Andrew M. Tidball, Grace N. Johnecheck, Larry L. Louters, Brendan D. Looyenga, Janelle Rekman
Publikováno v:
Biochimie. 151
Quercetin, a common dietary flavone, is a competitive inhibitor of glucose uptake and is also thought to be transported into cells by GLUT1. In this study, we confirm that quercetin is a competitive inhibitor of GLUT1 and also demonstrate that newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731cd0028760fbf54f6c98ff19f17fdf
https://pubmed.ncbi.nlm.nih.gov/29857184
https://pubmed.ncbi.nlm.nih.gov/29857184
Autor:
Brendan D. Looyenga, Larry L. Louters, Brianna M. Busscher, Lauren E. Strohbehn, Kylee A. Rosette, Leesha K. Gunnink, Jeremy A. Wodarek
Caffeine has been shown to be a robust uncompetitive inhibitor of glucose uptake in erythrocytes. It preferentially binds to the nucleotide-binding site on GLUT1 in its tetrameric form and mimics the inhibitory action of ATP. Here we demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c796cc536f26814733f55595378f6e80
https://europepmc.org/articles/PMC6141003/
https://europepmc.org/articles/PMC6141003/
Autor:
Benjamin D. Kuiper, Stephen M. Gunnink, Larry L. Louters, Samuel A. Kerk, Emily Braun, Ola D. Alabi
Publikováno v:
Life Sciences. 102:105-110
Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd594cd1c2aea0326b7602dea124b8b6
https://doi.org/10.1016/j.lfs.2014.03.017
https://doi.org/10.1016/j.lfs.2014.03.017
Autor:
Larry L. Louters, Stephen M. Gunnink, Benjamin D. Kuiper, David P. Kuipers, Ola D. Alabi, Jared P. Scripture
Publikováno v:
Biochimie. 95:787-792
Nitroxyl (HNO) has a unique, but varied, set of biological properties including beneficial effects on cardiac contractility and stimulation of glucose uptake by GLUT1. These biological effects are largely initiated by HNO's reaction with cysteine res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb5c1c9d8493a5491b3004402e33291
https://doi.org/10.1016/j.biochi.2012.11.006
https://doi.org/10.1016/j.biochi.2012.11.006