Preclinical safety profile of sildenafil

Autor: P Graepel, Claude Charuel, P Comby, A. Lodola, D Abbott, C Peters, G Paulus, J Stadler, L. Longeart, Bernard Leblanc, Gilles Hanton

Publikováno v: International Journal of Impotence Research. 16:498-504

Sildenafil citrate, marketed as Viagra, for the treatment of erectile dysfunction, has a proven record of safety in humans as predicted by the results of extensive pharmacological and toxicological testing in animals and in vitro, and confirmed by ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2144c03537d0a76263917ba0847c12
https://doi.org/10.1038/sj.ijir.3901232

Fat, Frail and Dying Young: Survival, Body Weight and Pathology of the Charles River Sprague-Dawley-Derived Rat Prior to and Since the Introduction of the VAFR Variant in 1988

Autor: B. Geffray, J.P. Provost, A. Lodola, G.J. Nohynek, L. Longeart

Publikováno v: Human & Experimental Toxicology. 12:87-98

Trends in survival and body weight were evaluated in 2140 control Sprague-Dawley-derived [Crl: COBS-CD(SD)BR and Crl: COBS-VAF CD(SD)BR] rats used for 24-month rat carcinogenicity studies between 1979 and 1991, Body weight and survival were remarkabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0807163db9729f37c5c074e70be2758c
https://doi.org/10.1177/096032719301200201

Multiple Pigmented Cutaneous Papules Associated with a Novel Canine Papillomavirus in an Immunosuppressed Dog

Autor: C. George, J. P. Sundberg, G. Orth, Patricia Cassonnet, L. Longeart, L. Poisson, J.L. Le Net, M.-T. Masson

Publikováno v: Veterinary Pathology
Veterinary Pathology, SAGE Publications, 1997, 34 (1), pp.8-14. ⟨10.1177/030098589703400102⟩
Veterinary Pathology, 1997, 34 (1), pp.8-14. ⟨10.1177/030098589703400102⟩

Part of this information was presented as a poster at the Second Wolrd Congress of Veterinary Dermatology in Montréal (Canada), 13-16 May 1992.; International audience; Cutaneous papillomavirus infection was diagnosed in a 6-year-old female Boxer do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e27ea99f17ba65154b12b087a807f3
https://hal-pasteur.archives-ouvertes.fr/pasteur-02939612

Histochemical study of cutaneous mucins in hypothyroid dogs

Autor: J. P. Magnol, L. Longeart, J. More, Alain Regnier, S. Doliger, Maxence Delverdier

Publikováno v: Veterinary pathology. 32(6)

A dermal mucinoisis, visualized as dermal alcianophilic material, is occasionally present in canine hypothyroidism (myxedema). Various histochemical reactions (alcian blue/periodic acid–Schiff [PAS], alcian blue at pH 2.6, alcian blue at pH 1.0, cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1863d38e5123e448f2f467436adeb98a
https://pubmed.ncbi.nlm.nih.gov/8592797

Granulomatous enteritis in a dromedary (Camelus dromedarius) due to green algal infection

Autor: M. Fadl Ahmed, J.L. Le Net, Gilles Saint-Martin, M.-T. Masson, C. Montois, L. Longeart

Publikováno v: Veterinary Pathology

In mammals, infections caused by unicellular algae are rare, and most have been due to the achlorophyllous microorganisms Prototheca spp. Pathogenicity of green algae in animals was first recognized in 1973 by Cordy, who reported a case of necrotizin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fef3a2700b5e9e9933f1ec4189c29f
http://agritrop.cirad.fr/394962/