Zobrazeno 1 - 10
of 55
pro vyhledávání: '"L. Lancioni"'
Autor:
Christopher Lwanga, Peace Aber, Kirkby D. Tickell, Moses M. Ngari, John Mukisa, Michael Atuhairwe, Lindsay Brown, Ezekiel Mupere, Isabel Potani, Lubaba Shahrin, Brooks Morgan, Benson O. Singa, Victoria Nankabirwa, Richard K. Mugambe, Zakaria Mukasa, Judd L. Walson, James A. Berkley, Christina L. Lancioni
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Although mortality risk associated with HIV is well described, HIV-exposed uninfected (HEU) young children are also at increased risk of hospitalization and death as compared to HIV-unexposed uninfected (HUU) children. The drivers
Externí odkaz:
https://doaj.org/article/1311d6c8c0fb4efb8c80bbe8d7a3c608
Autor:
Evans O. Mudibo, Jasper Bogaert, Caroline Tigoi, Moses M. Ngari, Benson O. Singa, Christina L. Lancioni, Abdoulaye Hama Diallo, Emmie Mbale, Ezekiel Mupere, John Mukisa, Johnstone Thitiri, Molline Timbwa, Elisha Omer, Narshion Ngao, Robert Musyimi, Eunice Kahindi, Roseline Maïmouna Bamouni, Robert H. J. Bandsma, Paul Kelly, Andrew J. Prendergast, Christine J. McGrath, Kirkby D. Tickell, Judd L. Walson, James A. Berkley, James M. Njunge, Gerard Bryan Gonzales
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract In sub-Saharan Africa, children with severe malnutrition (SM) and HIV have substantially worse outcomes than children with SM alone, facing higher mortality risk and impaired nutritional recovery post-hospitalisation. Biological mechanisms u
Externí odkaz:
https://doaj.org/article/b68648dbd6c04467a38c36dc19f714a1
Autor:
Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Al Fazal Khan, Ali Faisal Saleem, Benson O. Singa, Blaise Siézan Gnoumou, Caroline Tigoi, Catherine Achieng, Celine Bourdon, Chris Oduol, Christina L. Lancioni, Christine Manyasi, Christine J. McGrath, Christopher Maronga, Christopher Lwanga, Daniella Brals, Dilruba Ahmed, Dinesh Mondal, Donna M. Denno, Dorothy I. Mangale, Emmanuel Chimezi, Emmie Mbale, Ezekiel Mupere, Gazi Md. Salauddin Mamun, Issaka Ouédraogo, James A. Berkley, Jenala Njirammadzi, John Mukisa, Johnstone Thitiri, Judd L. Walson, Julie Jemutai, Kirkby D. Tickell, Lubaba Shahrin, MacPherson Mallewa, Md. Iqbal Hossain, Mohammod Jobayer Chisti, Molly Timbwa, Moses Mburu, Moses M. Ngari, Narshion Ngao, Peace Aber, Philliness Prisca Harawa, Priya Sukhtankar, Robert H.J. Bandsma, Roseline Maïmouna Bamouni, Sassy Molyneux, Shalton Mwaringa, Shamsun Nahar Shaima, Syed Asad Ali, Syeda Momena Afsana, Syera Banu, Tahmeed Ahmed, Wieger P. Voskuijl, Zaubina Kazi
Publikováno v:
EClinicalMedicine, Vol 73, Iss , Pp 102676- (2024)
Summary: Background: Children in low and middle-income countries remain vulnerable following hospital-discharge. We estimated the incidence and correlates of hospital readmission among young children admitted to nine hospitals in sub-Saharan Africa a
Externí odkaz:
https://doaj.org/article/566c940b2f5041ee92176a2e4837be2f
Autor:
Celine Bourdon, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Md Alfazal Khan, Ali Faisal Saleem, Benson O. Singa, Blaise Siézanga Gnoumou, Caroline Tigoi, Catherine Achieng Otieno, Chrisantus Odhiambo Oduol, Christina L. Lancioni, Christine Manyasi, Christine J. McGrath, Christopher Maronga, Christopher Lwanga, Daniella Brals, Dilruba Ahmed, Dinesh Mondal, Donna M. Denno, Dorothy I. Mangale, Emmanuel Chimwezi, Emmie Mbale, Ezekiel Mupere, Gazi Md Salauddin Mamun, Issaka Ouédraogo, James A. Berkley, James M. Njunge, Jenala Njirammadzi, John Mukisa, Johnstone Thitiri, Judd L. Walson, Julie Jemutai, Kirkby D. Tickell, Lubaba Shahrin, Macpherson Mallewa, Md Iqbal Hossain, Mohammod Jobayer Chisti, Molline Timbwa, Moses Mburu, Moses M. Ngari, Narshion Ngao, Peace Aber, Philliness Prisca Harawa, Priya Sukhtankar, Robert H.J. Bandsma, Roseline Maïmouna Bamouni, Sassy Molyneux, Shalton Mwaringa, Shamsun Nahar Shaima, Syed Asad Ali, Syeda Momena Afsana, Sayera Banu, Tahmeed Ahmed, Wieger P. Voskuijl, Zaubina Kazi
Publikováno v:
EClinicalMedicine, Vol 70, Iss , Pp 102530- (2024)
Summary: Background: Growth faltering is well-recognized during acute childhood illness and growth acceleration during convalescence, with or without nutritional therapy, may occur. However, there are limited recent data on growth after hospitalizati
Externí odkaz:
https://doaj.org/article/d610a35af7a54ebe9f946ea362e94129
Autor:
Mehakpreet K. Thind, Holm H. Uhlig, Michael Glogauer, Nades Palaniyar, Celine Bourdon, Agnes Gwela, Christina L. Lancioni, James A. Berkley, Robert H. J. Bandsma, Amber Farooqui
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Neutrophils are the most abundant innate immune cells. Multiple mechanisms allow them to engage a wide range of metabolic pathways for biosynthesis and bioenergetics for mediating biological processes such as development in the bone marrow and antimi
Externí odkaz:
https://doaj.org/article/a712023bbd084f07aa78d73cef54169e
Autor:
Erin Morrow, Qijia Liu, Sarah Kiguli, Gwendolyn Swarbrick, Mary Nsereko, Megan D. Null, Meghan Cansler, Harriet Mayanja-Kizza, W. Henry Boom, Phalkun Chheng, Melissa R. Nyendak, David M. Lewinsohn, Deborah A. Lewinsohn, Christina L. Lancioni
Publikováno v:
Pathogens, Vol 12, Iss 11, p 1353 (2023)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of pediatric morbidity and mortality. Young children are at high risk of TB following Mtb exposure, and this vulnerability is secondary to insufficient host immuni
Externí odkaz:
https://doaj.org/article/cebbe528c24541dfa889784b98a9c952
Autor:
Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Ali Fazal Khan, Ali Faisal Saleem, Benson O. Singa, Blaise Siezanga Gnoumou, Caroline Tigoi, Catherine Achieng Otieno, Celine Bourdon, Chris Odhiambo Oduol, Christina L. Lancioni, Christine Manyasi, Christine J. McGrath, Christopher Maronga, Christopher Lwanga, Daniella Brals, Dilruba Ahmed, Dinesh Mondal, Donna M. Denno, Dorothy I. Mangale, Emmanuel Chimezi, Emmie Mbale, Ezekiel Mupere, Gazi Md. Salahuddin Mamun, Issaka Ouedraogo, George Githinji, James A. Berkley, Jenala Njirammadzi, John Mukisa, Johnstone Thitiri, Jonas Haggstrom, Joseph D. Carreon, Judd L. Walson, Julie Jemutai, Kirkby D. Tickell, Lubaba Shahrin, MacPherson Mallewa, Md. Iqbal Hossain, Mohammod Jobayer Chisti, Molly Timbwa, Moses Mburu, Moses M. Ngari, Narshion Ngao, Peace Aber, Philliness Prisca Harawa, Priya Sukhtankar, Robert H.J. Bandsma, Roseline Maimouna Bamouni, Sassy Molyneux, Sergey Feldman, Shalton Mwaringa, Shamsun Nahar Shaima, Syed Asad Ali, Syeda Momena Afsana, Syera Banu, Tahmeed Ahmed, Wieger P. Voskuijl, Zaubina Kazi
Publikováno v:
EClinicalMedicine, Vol 57, Iss , Pp 101838- (2023)
Summary: Background: A better understanding of which children are likely to die during acute illness will help clinicians and policy makers target resources at the most vulnerable children. We used machine learning to characterise mortality in the 30
Externí odkaz:
https://doaj.org/article/f829cad9bd274d33bc06d7df05a813b0
Autor:
Albert Koulman, Kelsey Jones, James Berkley, Judd Walson, Eric Houpt, David S. Wishart, Christina L. Lancioni, Moses Ngari, Lei Xia, James M. Njunge, Abdoulaye Hama Diallo, Kirkby Tickell, Md. Amran Gazi, Abu Sadat Mohammad Sayeem Bin Shahid, Zaubina Kazi, Ali Saleem, Caroline Tigoi, Syed Ali, Emily Yoshioka, Ezekiel Mupere, Moses Mburu, Mohammod Jobayer Chisti, Bonface Gichuki, Narshion Ngao, Wilson Gumbi, Elisha Omer, Robert Bandsma, Benson Singa, Wieger Voskuijl, Tahmeed Ahmed, Alex Macharia, Thomas N. Williams, Anna Mitchel, Johnstone Makale, Joe Gogain, Jessica Williams, Rupasri Mandal, Nebojsa Janjic, Michael Routledge, Hang Wu, Camilo Espinosa, Yun Yun Gong, Jie Liu, Nima Aghaeepour, Hilary Browne, Trevor D. Lawley, Doreen Rwigi, Yan Shao, Timothy Kaburu, Kevin Kariuki, Lisa Gartner, Holm H. Uhlig
Publikováno v:
Gates Open Research, Vol 6 (2022)
Introduction: Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest op
Externí odkaz:
https://doaj.org/article/4f784e51afb14738813820fdbf1f5a7d
Autor:
Ruth J. Napier, Ellen J. Lee, Michael P. Davey, Emily E. Vance, João M. Furtado, Paige E. Snow, Kimberly A. Samson, Sydney J. Lashley, Brieanna R. Brown, Reiko Horai, Mary J. Mattapallil, Biying Xu, Michelle C. Callegan, Luke S. Uebelhoer, Christina L. Lancioni, Richard K. Vehe, Bryce A. Binstadt, Justine R. Smith, Rachel R. Caspi, Holly L. Rosenzweig
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
How mutations in the microbial receptor NOD2 induce Blau syndrome in humans and related uveitis is unclear. Here the authors show, using Nod2-deficient mice and experimental uveitis, that Nod2 negatively regulates T cell activation and transcription
Externí odkaz:
https://doaj.org/article/5c09fe5a329b4c398f56c7642549fe79
Autor:
Michelle L. Underwood, Byung Park, Luke S. Uebelhoer, Geoffrey Gu, Lynn E. Kunkel, Philip T. Korthuis, Ryan R. Cook, Rafick Pierre Sekaly, Susan Pereira Ribeiro, Christina L. Lancioni
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite advances in antiretroviral therapy, chronic immune activation continues to be observed among individuals with well-controlled HIV viral loads, and is associated with non-AIDS defining morbidities among people living with HIV. Alcohol use diso
Externí odkaz:
https://doaj.org/article/7121c15dcf3e4788b335243beb7cdbb4