Zobrazeno 1 - 10
of 16
pro vyhledávání: '"L. L. Pragina"'
Publikováno v:
Moscow University Biological Sciences Bulletin. 63:141-144
The effects of the DNA-containing biologically active compound polidan on conditioning in rats were investigated. Passive avoidance conditioning was used as a model of memory. Polidan at a dose of 10−10 M had a positive effect on memory.
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 66(6)
New experimental data on the mnemotropic (nootropic) properties of the well-known drug polidan (a DNA derivative) are summarized. The results obtained by histological techniques showed changes in the brain structure, indicating protein synthesis acti
Autor:
A. G. Solov'ev, K. Z. Gumargalieva, E. B. Burlakova, L. L. Pragina, N. A. Tushmalova, A. N. Inozemtsev
Publikováno v:
Bulletin of Experimental Biology and Medicine. 120:706-708
Effects of low doses of piracetam, a psychotropic nootropic, on the memory of rats are studied. A positive effect of the drug in a dose many times lower than the doses used routinely is demonstrated on a model of elaboration of the active avoidance r
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 64(6)
The effect of piracetam on the development of a two-link system of feed-procuring conditioned reflexes was studied in rats with probability reinforcement. The experiments showed that piracetam improves both the current learning process and the memory
Autor:
Yu. V. Burov, S. V. Litvinova, A. N. Inozemcev, N. A. Tushmalova, O. V. Karpukhina, L. L. Pragina
Publikováno v:
Bulletin of Experimental Biology and Medicine. 115:150-152
Publikováno v:
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 51(2)
In the paper are presented the results of the study of Pyavit, a complex leech preparation from, whose effects on the memory may be dependent on DNA methylation (one of the mechanisms of gene expression regulation). A positive effect of Pyavit on for
Publikováno v:
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 49(5)
Effect of DNA derivative of biological origin on rat memory was studied. The positive influence of the drug on formation of memory trace and retention was shown. The results are discussed in the frames of the hypothesis of the common molecular mechan
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 62(4)
The authors studied the effect of the actoprotector bemitil on the conditional-reflex memory of rats and its functional disorder by disturbance of the cause-effect (abatement of the avoidance reaction) or space relations. Intraperitoneal injections o
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 59(6)
Emotional stress was caused in rats by changing the location of the gate in the shuttle chamber through which training had been accomplished in the previous experiments. The procedure led to disorder of the avoidance response (AR) and increase of int
Autor:
N A, Tushmalova, L L, Pragina, A N, Inozemtsev, K Z, Gumargalieva, A G, Solov'ev, E B, Burlakova
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 120(7)