Zobrazeno 1 - 5
of 5
pro vyhledávání: '"L. L. Kerman"'
Autor:
Paul G. Conway, Joachim E. Roehr, Kendra L. Burgher, Jurcak John G, L. L. Kerman, Harold B. Hartman, Hrib Nicholas J, Woods Ann Theresa
Publikováno v:
Journal of Medicinal Chemistry. 37:2308-2314
A series of benzisoxaazole- and benzisothiazole-3-carboxamides has been prepared and tested for potential antipsychotic activity. In general, the compounds showed an affinity for dopamine D 2 and serotonin 5HT 2A and 5HT 1A receptors. Several members
Autor:
Paul G. Conway, Joachim E. Roehr, Hrib Nicholas J, L. L. Kerman, Kendra L. Burgher, Jurcak John G, Woods Ann Theresa, Harold B. Hartman
Publikováno v:
ChemInform. 25
A series of benzisoxaazole- and benzisothiazole-3-carboxamides has been prepared and tested for potential antipsychotic activity. In general, the compounds showed an affinity for dopamine D 2 and serotonin 5HT 2A and 5HT 1A receptors. Several members
Autor:
Mark R. Szewczak, H. B. Hartmann, S. Kongsamut, L. L. Kerman, A. T. Woods-Kettelberger, R. Corbett, Kendra L. Burgher, Jurcak John G, Hrib Nicholas J, D. E. Bregna, Joachim E. Roehr, S. Kafka
Publikováno v:
ChemInform. 28
Autor:
Roy Corbett, A. T. Woods, F. Camacho, Robert W. Dunn, L. L. Kerman, Rod J. Fishkin, K. Brooks
Publikováno v:
Psychopharmacology. 120(1)
Antipsychotic agents were tested for their ability to antagonize both dopaminergic-induced and non-competitive N-methyl-D-aspartate (NMDA) antagonist-induced behaviors. All of the agents dose-dependently antagonized the apomorphine-induced climbing m
Autor:
L. L. Kerman, A. T. Woods, R. Corbett, P.C. Conway, J.T. Strupczewski, H. Hartman, R.W. Dunn, G.C. Helsley
Publikováno v:
Pharmacology, biochemistry, and behavior. 45(1)
There are numerous preclinical screening procedures that are predictive of clinical efficacy for the positive symptoms of schizophrenia but no assays for the negative symptoms such as social withdrawal. In the social interaction test in rats, the aty