Výsledky vyhledávání - "L. Kubovcakova"

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Akademický článek

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Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes in Dopamine-��-Hydroxylase- and CRH-Knockout Mice Exposed to Stress

Autor: Andrej Tillinger, Olga Krizanova, Esther L. Sabban, L. Kubovcakova, Steven A. Thomas, Richard Kvetňanský

Publikováno v: Annals of the New York Academy of Sciences. 1148:257-268

Norepinephrine-deficient mice harbor a disruption of the gene for dopamine-beta-hydroxylase (DBH-KO). Corticotropin-releasing hormone knockout mice (CRH-KO) have markedly reduced HPA activity. The aim of the present work was to study how deficiency o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0800eb6264e7aee693d26fc5229f9d
https://doi.org/10.1196/annals.1410.033

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Hypoxia modulates gene expression of IP3 receptors in rodent cerebellum

Autor: D. Jurkovicova, J. Kopacek, P. Stefanik, L. Kubovcakova, A. Zahradnikova, S. Pastorekova, O Krizanova

Publikováno v: Pflügers Archiv - European Journal of Physiology. 454:415-425

Hypoxic brain cell injury is a complex process that results from a series of intracellular events. In this work, we tested whether severe hypoxia for 6 h can affect gene expression and protein levels of intracellular calcium channels, ryanodine recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c8dc1d8c3f1578aa8088e48f126189
https://doi.org/10.1007/s00424-007-0214-6

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Adrenergic and calcium modulation of the heart in stress: From molecular biology to function

Autor: Dana Jurkovicova, L. Kubovcakova, Andrej Tillinger, Olga Krizanova, Jaromir Myslivecek

Publikováno v: Stress. 10:173-184

There is strong evidence about the importance of catecholamines and calcium signaling in heart function. Also, interaction of these two systems is well documented. Catecholamines signal through adrenergic receptors, and further activate calcium trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f92f6e01a879c5bf7dce65361c992a8
https://doi.org/10.1080/10253890701305754

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Identification of phenylethanolamine N-methyltransferase gene expression in stellate ganglia and its modulation by stress

Autor: Olga Krizanova, Esther L. Sabban, Z. Bartosova, L. Kubovcakova, Lucia Micutkova, Richard Kvetnansky

Publikováno v: Journal of Neurochemistry. 97:1419-1430

Phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28) is the terminal enzyme of the catecholaminergic pathway converting noradrenaline to adrenaline. Although preferentially localized in adrenal medulla, evidence exists that PNMT activity and ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c11037e020a7286f8e579937be6b04
https://doi.org/10.1111/j.1471-4159.2006.03832.x

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Gene Expression of Phenylethanolamine N-Methyltransferase in Corticotropin-Releasing Hormone Knockout Mice During Stress Exposure

Autor: Andrej Tillinger, Lucia Micutkova, Richard Kvetnansky, Olga Krizanova, Esther L. Sabban, L. Kubovcakova

Publikováno v: Cellular and Molecular Neurobiology. 26:733-752

1. Aims: Epinephrine (EPI) synthesizing enzyme phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28) is primarily localized in the adrenal medulla (AM). We have recently described existence of the PNMT gene expression in cardiac atria and ventri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e63b4ba781e930c834d50123ab8a421
https://doi.org/10.1007/s10571-006-9063-7

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Adrenergic modulation of the type 1 IP3 receptors in the rat heart

Autor: Dana Jurkovicova, Sona Hudecova, Richard Kvetnansky, L. Kubovcakova, Olga Krizanova

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1763(1):18-24

Inositol 1,4,5-trisphosphate (IP3) receptors are calcium-releasing channels localized on the sarcoplasmic reticulum. IP3 receptors mediate the calcium mobilizing effect of a wide range of hormones, cytokines, and neurotransmitters and play an importa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d9ebf77dbb33a657bd1302f38b818d

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Quantitative Evaluation of Catecholamine Enzymes Gene Expression in Adrenal Medulla and Sympathetic Ganglia of Stressed Rats

Autor: Lucia Micutkova, Maxim L. Filipenko, Olga Krizanova, Boris Mravec, N Rychkova, Esther L. Sabban, Richard Kvetnansky, L. Kubovcakova

Publikováno v: Annals of the New York Academy of Sciences. 1018:356-369

Stress-induced changes in mRNA levels of tyrosine hydroxylase (TH), dopamine-beta-hydroxylase (DBH), and phenylethanolamine N-methyltransferase (PNMT) have been expressed as relative arbitrary units compared with a control group. The aim of this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5922ab213fa2c4de7bd823df0e047bb2
https://doi.org/10.1196/annals.1296.045

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Immobilization Stress-Induced Increase in Plasma Catecholamine Levels Is Inhibited by a Prolactoliberin (Salsolinol) Administration

Autor: György M. Nagy, Boris Mravec, L. Kubovcakova, Marton Fekete, Ibolya Bodnár, Richard Kvetnansky

Publikováno v: Annals of the New York Academy of Sciences. 1018:124-130

Catecholamines (CAs) are significantly involved in the regulation of homeostasis of the organism at rest and especially during stressful situations. Stress induces increases in plasma CA (epinephrine and norepinephrine) levels and prolactin (PRL) rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54037adcc1b6e6460e98edeb8212a5dd
https://doi.org/10.1196/annals.1296.014

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