Zobrazeno 1 - 10
of 85
pro vyhledávání: '"L. Kruidenier"'
Autor:
L. Kruidenier, H. W. Verspaget
Publikováno v:
Mediators of Inflammation, Vol 7, Iss 3, Pp 157-162 (1998)
Oxidative damage is involved in the pathogenic process of idiopathic chronic inflammatory bowel disease. Although specific intervention in the oxidative cascade showed promising results in animal models and preliminary patient trials, the clinical ef
Externí odkaz:
https://doaj.org/article/b8895345b1f84c05b49440364ea0e3b7
Autor:
Hein W. Verspaget, R. A. van Hogezand, Cornelis B.H.W. Lamers, L. Kruidenier, M. van den Berg, W. van Duijn, Cornelis F. M. Sier, M.J.W. Meijer, F.J.G.M. Kubben, Qiang Gao
Publikováno v:
Digestive and Liver Disease. 37:584-592
Background/aims. Matrix metalloproteinases are major contributors in the breakdown and reconstitution of basement membranes and extracellular matrix in pathophysiological processes. We assessed the expression of matrix metalloproteinases-2 and -9 in
Autor:
Dick Jaarsma, Marieke E. van Meeteren, Freek J. Zijlstra, Cornelis B.H.W. Lamers, Ineke Kuiper, Hein W. Verspaget, L. Kruidenier
Publikováno v:
Free Radical Biology and Medicine, 34(6), 753-765. Elsevier Inc.
Mucosal tissue damage in chronic inflammatory bowel disease (IBD) is partly caused by an enduring exposure to excessive amounts of reactive oxygen metabolites (ROM). To protect themselves from the toxic effects of ROM, most intestinal cell types cons
Autor:
Ruud A van Hogezand, Wim van Duijn, Marij A C Mieremet-Ooms, L. Kruidenier, Cornelis B.H.W. Lamers, Ineke Kuiper, Hein W. Verspaget
Publikováno v:
The Journal of Pathology. 201:17-27
Intestinal mucosal damage in the inflammatory bowel diseases (IBD) Crohn's disease (CD) and ulcerative colitis (UC) involves reactive oxygen metabolites (ROMs). ROMs are neutralized by endogenous antioxidant enzymes in a carefully balanced two-step p
Differential mucosal expression of three superoxide dismutase isoforms in inflammatory bowel disease
Autor:
L. Kruidenier, Stefan L. Marklund, Ineke Kuiper, Hein W. Verspaget, Ruud A van Hogezand, Cornelis B.H.W. Lamers, Wim van Duijn
Publikováno v:
The Journal of Pathology. 201:7-16
Mucosal tissue damage and dysfunction in chronic inflammatory bowel disease (IBD) are partly caused by an enduring exposure to excessive amounts of reactive oxygen metabolites (ROMs). Although the three human isoforms of superoxide dismutase (SOD), c
Autor:
Hein W. Verspaget, L. Kruidenier
Publikováno v:
Alimentary Pharmacology & Therapeutics. 16:1997-2015
Summary Virtually all inflammatory mediators investigated to date seem to be dysregulated in the inflamed intestinal mucosa of patients with inflammatory bowel disease. However, which of these are actually involved in the initiation and perpetuation
Autor:
L. Kruidenier, J.H.J.M. van Krieken, A. M. L. Janssen, Gerrit Griffioen, C.J.H. van de Velde, C. B. Bosman, Hein W. Verspaget, Cornelis B.H.W. Lamers
Publikováno v:
Journal of Cancer Research and Clinical Oncology, 125, 327-335
Journal of Cancer Research and Clinical Oncology, 125, pp. 327-335
Journal of Cancer Research and Clinical Oncology, 125, pp. 327-335
Purpose: The oxidant-antioxidant balance within tissues is thought to contribute to the development and progression of cancer. Previous investigations have indicated changes in this balance during the colorectal oncogenic process that merit further i
Publikováno v:
Water Research. 31:1333-1346
The significance of the presence in drinking water of the protozoan microparasites Cryptosporidium parvum and Giardia lamblia for public health may be analyzed by means of risk assessment. This requires quantitative knowledge of all the contributing
Publikováno v:
The Journal of pathology. 201(1)
Intestinal inflammation is accompanied by excessive production of reactive oxygen and nitrogen metabolites. In order to counteract their harmful effects, the intestinal mucosa contains an extensive system of antioxidants. It has previously been shown
Autor:
L, Kruidenier, H W, Verspaget
Publikováno v:
Alimentary pharmacologytherapeutics. 16(12)
Virtually all inflammatory mediators investigated to date seem to be dysregulated in the inflamed intestinal mucosa of patients with inflammatory bowel disease. However, which of these are actually involved in the initiation and perpetuation of intes