Zobrazeno 1 - 10
of 101
pro vyhledávání: '"L. Kreindler"'
Autor:
Valerie J. Ludbrook, Kate E. Hanrott, James L. Kreindler, Joanna E. Marks-Konczalik, Nick P. Bird, Debbie A. Hewens, Misba Beerahee, David J. Behm, Alyn Morice, Lorcan McGarvey, Sean M. Parker, Surinder S. Birring, Jaclyn Smith
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Objective Airway sensory nerves involved in the cough reflex are activated by adenosine triphosphate (ATP) agonism of P2X purinoceptor 3 (P2X3) receptors. Transient receptor potential vanilloid 4 (TRPV4) channel activation causes ATP release from air
Externí odkaz:
https://doaj.org/article/8898a21c0e9847d39d530aa3f6cd63d4
Autor:
Anju T. Peters, Lindsay G.S. Bengtson, Yen Chung, Benjamin Emmanuel, Rohit K. Katial, James L. Kreindler, Cori J. Blauer-Peterson, Greg E. Davis
Publikováno v:
Allergy and asthma proceedings. 43(5)
Background: Limited data exist on the clinical and economic burden of chronic rhinosinusitis with nasal polyposis (CRSwNP). Objective: To describe patient characteristics, health-care resource utilization (HCRU), and health-care costs among patients
Autor:
Marcelo B. Antunes, Bradford A. Woodworth, Geeta Bhargave, Guoxiang Xiong, Jorge L. Aguilar, Adam J. Ratner, James L. Kreindler, Ronald C. Rubenstein, Noam A. Cohen
Publikováno v:
BioTechniques, Vol 43, Iss 2, Pp 195-204 (2007)
Air-liquid interface models using murine tracheal respiratory epithelium have revolutionized the in vitro study of pulmonary diseases. This model is often impractical because of the small number of respiratory epithelial cells that can be isolated fr
Externí odkaz:
https://doaj.org/article/15662775c40c4e88b1ea0ecc827362aa
Publikováno v:
Frontiers in Pediatrics, Vol 2 (2014)
While the founders of Pediatric Pulmonology recognized the necessity of research as a vital part of the developing sub-specialty, the field has struggled to develop and maintain physician-scientists and investigators. The clinical growth in Pediatric
Externí odkaz:
https://doaj.org/article/6c71bb3283d2493d84ef570ed25feb1f
Autor:
Kelly M Adams, Valsamma Abraham, Daniel Spielman, Jay K Kolls, Ronald C Rubenstein, Gregory E Conner, Noam A Cohen, James L Kreindler
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103263 (2014)
The epithelium plays an active role in the response to inhaled pathogens in part by responding to signals from the immune system. Epithelial responses may include changes in chemokine expression, increased mucin production and antimicrobial peptide s
Externí odkaz:
https://doaj.org/article/3c13e3caa28045f8818ec8952eb8a079
Autor:
Matthew J, Hegewald, Benjamin D, Horne, Frank, Trudo, James L, Kreindler, Yen, Chung, Susan, Rea, Denitza P, Blagev
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Purpose This retrospective, observational cohort study investigated the association of blood eosinophil counts within 1 week of hospitalization for acute exacerbation of COPD (AECOPD) with subsequent risk of all-cause and COPD-related readmission fro
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18280 (2011)
Barrett's esophagus (BE) is an intestinal metaplasia that occurs in the setting of chronic acid and bile reflux and is associated with a risk for adenocarcinoma. Expression of intestine-specific transcription factors in the esophagus likely contribut
Externí odkaz:
https://doaj.org/article/7ad67009390340649acaed59a9af978e
Autor:
Kong Chen, Derek A Pociask, Jeremy P McAleer, Yvonne R Chan, John F Alcorn, James L Kreindler, Matthew R Keyser, Steven D Shapiro, A McGarry Houghton, Jay K Kolls, Mingquan Zheng
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20333 (2011)
Chronic Obstructive Pulmonary Disease (COPD) is characterized by airspace enlargement and peribronchial lymphoid follicles; however, the immunological mechanisms leading to these pathologic changes remain undefined. Here we show that cigarette smoke
Externí odkaz:
https://doaj.org/article/50301d1cf40c4f6384de173cb992c82e
Autor:
Natalia Goldstein-Daruech, Emily K Cope, Ke-Qing Zhao, Katarina Vukovic, Jennifer M Kofonow, Laurel Doghramji, Bernardo González, Alexander G Chiu, David W Kennedy, James N Palmer, Jeffery G Leid, James L Kreindler, Noam A Cohen
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15700 (2011)
Cigarette smokers and those exposed to second hand smoke are more susceptible to life threatening infection than non-smokers. While much is known about the devastating effect tobacco exposure has on the human body, less is known about the effect of t
Externí odkaz:
https://doaj.org/article/bbdedc33f8c148bd974b3a6519f23da6
Autor:
Paul Connolly, Aili L. Lazaar, Bruce E. Miller, Wayne Matthews, Richard Lloyd, Sarah Keel, Nicholas P. Henley, Claire Ambery, Neil Hodnett, Helen Garden, Jackie C. Bloomer, John Yonchuk, James L. Kreindler
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 117:224-231
The natural variability of gastric pH or gastric acid reducing medications can result in lower and more variable clinical pharmacokinetics for basic compounds in patient populations. Progressing alternative salt forms with improved solubility and dis