Zobrazeno 1 - 10
of 355
pro vyhledávání: '"L. Klibanov"'
Autor:
Pedro Norat, Jennifer D. Sokolowski, Catherine M. Gorick, Sauson Soldozy, Jeyan S. Kumar, Youngrok Chae, Kaan Yagmurlu, Joelle Nilak, Khadijeh A. Sharifi, Melanie Walker, Michael R. Levitt, Alexander L. Klibanov, Zhen Yan, Richard J. Price, Petr Tvrdik, Mohammad Yashar S. Kalani
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 3 (2023)
Background Transplantation of autologous mitochondria into ischemic tissue may mitigate injury caused by ischemia and reperfusion. Methods Using murine stroke models of middle cerebral artery occlusion, we sought to evaluate feasibility of delivery o
Externí odkaz:
https://doaj.org/article/a6e7164fe9c346a3b137fecd1e55ef7b
Autor:
Christopher Childers, Connor Edsall, Isabelle Mehochko, Waleed Mustafa, Yasemin Yuksel Durmaz, Alexander L. Klibanov, Jayasimha Rao, Eli Vlaisavljevich
Publikováno v:
BME Frontiers, Vol 2022 (2022)
Objective. This paper is an initial work towards developing particle-mediated histotripsy (PMH) as a novel method of treating catheter-based medical device (CBMD) intraluminal biofilms. Impact Statement. CBMDs commonly become infected with bacterial
Externí odkaz:
https://doaj.org/article/9be3961d35e64023b93f80c317b55ff1
Autor:
Alexander S. Mathew, Catherine M. Gorick, E. Andrew Thim, William J. Garrison, Alexander L. Klibanov, G. Wilson Miller, Natasha D. Sheybani, Richard J. Price
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 2, Pp n/a-n/a (2021)
Abstract Focused ultrasound (FUS) mediated blood–brain barrier disruption (BBBD) targets the delivery of systemically‐administered therapeutics to the central nervous system. Preclinical investigations of BBBD have been performed on different ane
Externí odkaz:
https://doaj.org/article/6fc627d9c0334aa891ed4c9e70257cac
Autor:
Alyssa B. Becker, Lanlin Chen, Bo Ning, Song Hu, John A. Hossack, Alexander L. Klibanov, Brian H. Annex, Brent A. French
Publikováno v:
Ultrasound Med Biol
Mouse models are critical in developing new therapeutic approaches to treat peripheral arterial disease (PAD). Despite decades of research and numerous clinical trials, the efficacy of available therapies is limited. This may suggest shortcomings in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1f3b3217af4bd17ecb41b161a1df08
https://doi.org/10.1016/j.ultrasmedbio.2022.02.002
https://doi.org/10.1016/j.ultrasmedbio.2022.02.002
Autor:
Dustin K Bauknight, Victoria Osinski, Siva Sai Krishna Dasa, Anh T Nguyen, Melissa A Marshall, Julia Hartman, Matthew Harms, Gavin O'Mahony, Jeremie Boucher, Alexander L Klibanov, Coleen A McNamara, Kimberly A Kelly
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224917 (2019)
Targeted nanoparticle delivery is a promising strategy for increasing efficacy and limiting side effects of therapeutics. When designing a targeted liposomal formulation, the in vivo biodistribution of the particles must be characterized to determine
Externí odkaz:
https://doaj.org/article/2da99baf72954ed7b9b321d93ecc7b32
Publikováno v:
Ultrasound Med Biol
Ultrasound molecular imaging techniques rely on the separation and identification of three types of signals: static tissue, adherent microbubbles and non-adherent microbubbles. In this study, the image filtering techniques of singular value threshold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b35d0f62b90b85c6de285413721f6ee
https://doi.org/10.1016/j.ultrasmedbio.2021.06.019
https://doi.org/10.1016/j.ultrasmedbio.2021.06.019
Autor:
Klazina Kooiman, Tom van Rooij, Bin Qin, Frits Mastik, Hendrik J Vos, Michel Versluis, Alexander L Klibanov, Nico de Jong, Flordeliza S Villanueva, Xucai Chen
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180747 (2017)
Acoustic behavior of lipid-coated microbubbles has been widely studied, which has led to several numerical microbubble dynamics models that incorporate lipid coating behavior, such as buckling and rupture. In this study we investigated the relationsh
Externí odkaz:
https://doaj.org/article/6633bcdd065c496fbb4abfc56d74a002
Autor:
Joseph C. Gigliotti, Aimee Zhang, Di Wu, Yikui Tian, Zequan Yang, Eric J. Charles, Alexander L. Klibanov, J. Hunter Mehaffey, Irving L. Kron
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 161:e297-e306
Objective Acute hyperglycemia during myocardial infarction worsens outcomes in part by inflammatory mechanisms. Pulsed ultrasound has anti-inflammatory potential in bone healing and neuromodulation. We hypothesized that pulsed ultrasound would attenu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ae090de05c904ef55cc0dd61516908
https://doi.org/10.1016/j.jtcvs.2019.10.096
https://doi.org/10.1016/j.jtcvs.2019.10.096
Autor:
Alexander L. Klibanov
Publikováno v:
Investigative Radiology. 56:50-61
Gas-filled microbubbles are currently in clinical use as blood pool contrast agents for ultrasound imaging. The goal of this review is to discuss the trends and issues related to these relatively unusual intravascular materials, which are not small m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::605765132737868479cc5dc7ef3b6f88
https://doi.org/10.1097/rli.0000000000000733
https://doi.org/10.1097/rli.0000000000000733
Autor:
John A. Hossack, F. William Mauldin, Sunil Unnikrishnan, Alexander L. Klibanov, Feifei Zhao, Elizabeth B. Herbst
Publikováno v:
Invest Radiol
OBJECTIVES Ultrasound contrast agents, consisting of gas-filled microbubbles (MBs), have been imaged using several techniques that include ultrasound localization microscopy and targeted molecular imaging. Each of these techniques aims to provide ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2d8441980b6393b5a527bb29907018
https://doi.org/10.1097/rli.0000000000000728
https://doi.org/10.1097/rli.0000000000000728