Zobrazeno 1 - 10
of 499
pro vyhledávání: '"L. Jefferson"'
Autor:
Corey J. Bolton, Omair A. Khan, Dandan Liu, Sydney Wilhoite, Logan Dumitrescu, Amalia Peterson, Kaj Blennow, Henrik Zetterberg, Timothy J. Hohman, Angela L. Jefferson, Katherine A. Gifford
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 11, Pp 2977-2986 (2024)
Abstract Objective This study examined the effect of cognitive status, education, and sex on the association between subjective cognitive decline (SCD) and Alzheimer's disease (AD) biomarkers in non‐demented older adults. Methods Vanderbilt Memory
Externí odkaz:
https://doaj.org/article/b82a3c97a2f8422bb0313931c9a5a88b
Autor:
Rebecca L. Winfree, Emma Nolan, Logan Dumitrescu, Kaj Blennow, Henrik Zetterberg, Katherine A. Gifford, Kimberly R. Pechman, Mabel Seto, Vladislav A. Petyuk, Yanling Wang, Julie Schneider, David A. Bennett, Angela L. Jefferson, Timothy J. Hohman, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Recent evidence suggests that Alzheimer’s disease (AD) genetic risk variants (rs1582763 and rs6591561) of the MS4A locus are genome-wide significant regulators of soluble TREM2 levels such that the minor allele of the protective variant (r
Externí odkaz:
https://doaj.org/article/7f931778e48b4a1db9dee9d86d867c84
Autor:
Derek B. Archer, Kurt Schilling, Niranjana Shashikumar, Varuna Jasodanand, Elizabeth E. Moore, Kimberly R. Pechman, Murat Bilgel, Lori L. Beason‐Held, Yang An, Andrea Shafer, Luigi Ferrucci, Shannon L. Risacher, Katherine A. Gifford, Bennett A. Landman, Angela L. Jefferson, Andrew J. Saykin, Susan M. Resnick, Timothy J. Hohman, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction It is unclear how rates of white matter microstructural decline differ between normal aging and abnormal aging. Methods Diffusion MRI data from several well‐established longitudinal cohorts of aging (Alzheimer's Disease Neuroi
Externí odkaz:
https://doaj.org/article/20540831140341e68e8fcfd1aa55351e
Autor:
Amy Brown, Hallie L. Jefferson, Ali Fatehi Hassanabad, Christopher Noss, Nicole Webb, Paul W. M. Fedak, William D. T. Kent, Corey Adams
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundThe NeoChord DS1000 system implants artificial neochords transapically, through a left mini-thoracotomy to treat degenerative mitral valve regurgitation (MR). Performed without cardiopulmonary bypass, neochord implantation and length adjust
Externí odkaz:
https://doaj.org/article/cca00f9c71734da6b3670cedbd02e496
Autor:
Yisu Yang, Kurt Schilling, Niranjana Shashikumar, Varuna Jasodanand, Elizabeth E. Moore, Kimberly R. Pechman, Murat Bilgel, Lori L. Beason‐Held, Yang An, Andrea Shafer, Shannon L. Risacher, Bennett A. Landman, Angela L. Jefferson, Andrew J. Saykin, Susan M. Resnick, Timothy J. Hohman, Derek B. Archer, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Introduction White matter microstructure may be abnormal along the Alzheimer's disease (AD) continuum. Methods Diffusion magnetic resonance imaging (dMRI) data from the Alzheimer's Disease Neuroimaging Initiative (ADNI, n = 627), Baltimore L
Externí odkaz:
https://doaj.org/article/76b466b757de4ea9a3c9302b583bdeda
Autor:
Corey J. Bolton, Omair A. Khan, Elizabeth E. Moore, Kimberly R. Pechman, L. Taylor Davis, Dandan Liu, Bennett A. Landman, Katherine A. Gifford, Timothy J. Hohman, Angela L. Jefferson
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103393- (2023)
Introduction: Functional independence is an essential predictor of quality of life in aging, yet few accessible predictors of functional decline have been identified. This study examined associations between baseline structural neuroimaging markers a
Externí odkaz:
https://doaj.org/article/ff2d236c6b894e25ab7ee1af6a34ea48
Autor:
Daniel E. Gustavson, Derek B. Archer, Jeremy A. Elman, Olivia K. Puckett, Christine Fennema-Notestine, Matthew S. Panizzon, Niranjana Shashikumar, Timothy J. Hohman, Angela L. Jefferson, Lisa T. Eyler, Linda K. McEvoy, Michael J. Lyons, Carol E. Franz, William S. Kremen
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103279- (2023)
Background: Studies have investigated white matter microstructure in relation to late-life cognitive impairments, with fractional anisotropy (FA) and mean diffusivity (MD) measures thought to capture demyelination and axonal degradation. However, new
Externí odkaz:
https://doaj.org/article/355ebd3acd9a443ea48e863f22872254
Autor:
Maji Hailemariam, Julia W. Felton, Kent Key, DeOnica Greer, Bernadel L. Jefferson, Janice Muhammad, Raven Miller, Fallon Richie, DeWaun Robinson, Sharon Saddler, Bryan Spencer, Monicia Summers, Jonne Mc Coy White, Jennifer E. Johnson
Publikováno v:
International Journal for Equity in Health, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background Equitable access to services that promote health and wellbeing is an important component of social justice. A community-engaged participatory qualitative study was conducted in Flint, Michigan, USA, to understand the needs of spec
Externí odkaz:
https://doaj.org/article/c99d82fc4de648458b114716ef331e95
Autor:
Katie E. Osborn, Omair A. Khan, Hailey A. Kresge, Corey W. Bown, Dandan Liu, Elizabeth E. Moore, Katherine A. Gifford, Lealani Mae Y. Acosta, Susan P. Bell, Timothy J. Hohman, Kaj Blennow, Henrik Zetterberg, Angela L. Jefferson
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 700-709 (2019)
Abstract Introduction Neuroaxonal damage may contribute to cognitive changes preceding clinical dementia. Accessible biomarkers are critical for detecting such damage. Methods Plasma and cerebrospinal fluid (CSF) neurofilament light (NFL) were relate
Externí odkaz:
https://doaj.org/article/f5a717ea79574a539830b9626e99931b
Autor:
Mabel Seto, Logan Dumitrescu, Emily R. Mahoney, Annah M. Sclafani, Philip L. De Jager, Vilas Menon, Mary E.I. Koran, Renã A. Robinson, Douglas M. Ruderfer, Nancy J. Cox, Nicholas T. Seyfried, Angela L. Jefferson, Julie A. Schneider, David A. Bennett, Vladislav A. Petyuk, Timothy J. Hohman
Publikováno v:
Neurobiol Aging
The Vascular Endothelial Growth Factor (VEGF) signaling family has been implicated in neuroprotection and clinical progression in Alzheimer’s disease (AD). Previous work in postmortem human dorsolateral prefrontal cortex demonstrated that higher tr