Zobrazeno 1 - 10
of 510
pro vyhledávání: '"L. James Lee"'
Autor:
Hong Li, Chi‐Ling Chiang, Kwang Joo Kwak, Xinyu Wang, Sital Doddi, Lakshmi V. Ramanathan, Sun M. Cho, Ya‐Chin Hou, Tai‐Shan Cheng, Xiaokui Mo, Yueh‐Shih Chang, Hui‐Lan Chang, Weiming Cheng, Wei‐Ni Tsai, Luong T. H. Nguyen, Junjie Pan, Yifan Ma, Xilal Y. Rima, Jingjing Zhang, Eduardo Reategui, Yeh‐Shiu Chu, Peter Mu‐Hsin Chang, Pei‐Hung Chang, Chi‐Ying F. Huang, Cheng‐Hsu Wang, Yan‐Shen Shan, Chung‐Pin Li, Martin Fleisher, L. James Lee
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Detecting pancreatic duct adenocarcinoma (PDAC) in its early stages and predicting late‐stage patient prognosis undergoing chemotherapy is challenging. This work shows that the activation of specific oncogenes leads to elevated expression
Externí odkaz:
https://doaj.org/article/a765cae34104438aa7abecd26a692173
Autor:
Chi-Ling Chiang, Yifan Ma, Ya-Chin Hou, Junjie Pan, Sin-Yu Chen, Ming-Hsien Chien, Zhi-Xuan Zhang, Wei-Hsiang Hsu, Xinyu Wang, Jingjing Zhang, Hong Li, Lili Sun, Shannon Fallen, Inyoul Lee, Xing-Yu Chen, Yeh-Shiu Chu, Chi Zhang, Tai-Shan Cheng, Wen Jiang, Betty Y. S. Kim, Eduardo Reategui, Robert Lee, Yuan Yuan, Hsiao-Chun Liu, Kai Wang, Michael Hsiao, Chi-Ying F. Huang, Yan-Shen Shan, Andrew S. Lee, L. James Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) tumours carry multiple gene mutations and respond poorly to treatments. There is currently an unmet need for drug carriers that can deliver multiple gene cargoes to target high solid tumour burden like
Externí odkaz:
https://doaj.org/article/af563ac9db814eeda373f30019d84562
Autor:
Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, DaeYong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R. Schrank, Adam J. Grippin, JongHoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K. Tang, L. James Lee, Andrew S. Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains
Externí odkaz:
https://doaj.org/article/daa7ff6703414ccab6b6c9e5982dab8f
Autor:
Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Luong T. H. Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, Kim Truc Nguyen, Karunya Albert, Minh‐Dao Duong‐Thi, Nicole Walters, Kwang Joo Kwak, Min Jin Yoon, Hong Li, Jacob Doon‐Ralls, Colin L. Hisey, Daeyong Lee, Yifan Wang, Jonghoon Ha, Kelsey Scherler, Shannon Fallen, Inyoul Lee, Andre F. Palmer, Wen Jiang, Setty M. Magaña, Kai Wang, Betty Y. S. Kim, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of EV bulk biomarker characterization. Herein, we present a
Externí odkaz:
https://doaj.org/article/793a6051126e4fb6a8e9f5fa55384db3
Autor:
Michela Saviana, Giulia Romano, Joseph McElroy, Giovanni Nigita, Rosario Distefano, Robin Toft, Federica Calore, Patricia Le, Daniel Del Valle Morales, Sarah Atmajoana, Stephen Deppen, Kai Wang, L. James Lee, Mario Acunzo, Patrick Nana-Sinkam
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSmall cell lung cancer (SCLC) is characterized by poor prognosis and challenging diagnosis. Screening in high-risk smokers results in a reduction in lung cancer mortality, however, screening efforts are primarily focused on non-small cell
Externí odkaz:
https://doaj.org/article/fde62c5e48d0426982529ada7d2ce1ad
Autor:
Luong T. H. Nguyen, Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Kwang Joo Kwak, Tamio Okimoto, Joseph Amann, Min Jin Yoon, Takehito Shukuya, Chi‐Ling Chiang, Nicole Walters, Yifan Ma, Donald Belcher, Hong Li, Andre F. Palmer, David P. Carbone, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 9, Pp n/a-n/a (2022)
Abstract Conventional PD‐L1 immunohistochemical tissue biopsies only predict 20%–40% of non‐small cell lung cancer (NSCLC) patients that will respond positively to anti‐PD‐1/PD‐L1 immunotherapy. Herein, we present an immunogold biochip to
Externí odkaz:
https://doaj.org/article/146b93eb927b403f95099c23ef145b70
Autor:
Bogdan Mateescu, Jennifer C. Jones, Roger P. Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T. Chiu, Robert J. Coffey, Saumya Das, Peter De Hoff, Andrew deMello, Crislyn D’Souza-Schorey, David Elashoff, Kiarash R. Eliato, Jeffrey L. Franklin, David J. Galas, Mark B. Gerstein, Ionita H. Ghiran, David B. Go, Stephen Gould, Tristan R. Grogan, James N. Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K. Jeppesen, Tijana Jovanovic-Talisman, Betty Y.S. Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R. Kitchen, Vaughan Knouse, Emily L. LaPlante, Carlito B. Lebrilla, L. James Lee, Kathleen M. Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L. Maddox, Kyle McCarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P. De Oliveira Junior, Michael E. Paulaitis, Tuan Anh Phu, Robert L. Raffai, Eduardo Reátegui, Matthew E. Roth, David A. Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K. Sood, Stavros Stavrakis, Alessandra Stürchler, Muneesh Tewari, Juan P. Tosar, Alexander K. Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C. Vickers, Lucia Vojtech, Wyatt N. Vreeland, Ceming Wang, Kai Wang, ZeYu Wang, Joshua A. Welsh, Kenneth W. Witwer, David T.W. Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikołaj P. Zaborowski, Chenguang Zhang, Qin Zhang, Angela M. Zivkovic, Louise C. Laurent
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104653- (2022)
Summary: The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013–2018), Phase 2 of the progr
Externí odkaz:
https://doaj.org/article/d72ed055b3ab4740b73e722d85b82959
Autor:
Jingjing Zhang, Luong T. H. Nguyen, Richard Hickey, Nicole Walters, Xinyu Wang, Kwang Joo Kwak, L. James Lee, Andre F. Palmer, Eduardo Reátegui
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Extracellular vesicles (EVs) derived from tumor cells have the potential to provide a much-needed source of non-invasive molecular biomarkers for liquid biopsies. However, current methods for EV isolation have limited specificity towards tum
Externí odkaz:
https://doaj.org/article/1da76a5ccfd04a989da3fc36409bd677
Autor:
Zaizai Dong, Yanli Jiao, Bingteng Xie, Yongcun Hao, Pan Wang, Yuanyuan Liu, Junfeng Shi, Chandani Chitrakar, Stephen Black, Yu-Chieh Wang, L. James Lee, Mo Li, Yubo Fan, Lingqian Chang
Publikováno v:
Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-11 (2020)
Externí odkaz:
https://doaj.org/article/76f60bb7bde3482a8cd45f1fa33aa335
Autor:
Jian Zhou, Kwang Joo Kwak, Zuoren Wu, Dawei Yang, Jing Li, Meijia Chang, Yuanlin Song, Hengshan Zeng, L. James Lee, Jie Hu, Chunxue Bai
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 1909-1924 (2018)
Background/Aims: Tyrosine kinase inhibitor gefitinib significantly improves the survival of patients with non-small-cell lung cancer (NSCLC) by inhibiting epidermal growth factor receptor (EGFR) tyrosine kinase. However, patients eventually develop r
Externí odkaz:
https://doaj.org/article/42c57d59cd6b4fb8b1852bf8835bf13c