Zobrazeno 1 - 10
of 9 125
pro vyhledávání: '"L. James"'
Autor:
Elizabeth P. Lewis, Fatimah Al Khazal, Brandon Wilbanks, Naomi M. Gades, Patricia Ortega‐Sáenz, José López‐Barneo, Igor Adameyko, L. James Maher III
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 9, Pp 327-336 (2024)
Abstract In humans, loss of heterozygosity for defective alleles of any of the four subunits of mitochondrial tricarboxylic acid cycle enzyme succinate dehydrogenase (SDH, also Complex II of the electron transport chain) can lead to paraganglioma tum
Externí odkaz:
https://doaj.org/article/29cd999d7e6e4937bf53906a8080350f
Autor:
R. M. Naseer Khan, Yong-Mo Ahn, Gwendolyn A. Marriner, Laura E. Via, Francois D’Hooge, Seung Seo Lee, Nan Yang, Falguni Basuli, Alexander G. White, Jaime A. Tomko, L. James Frye, Charles A. Scanga, Danielle M. Weiner, Michelle L. Sutphen, Daniel M. Schimel, Emmanuel Dayao, Michaela K. Piazza, Felipe Gomez, William Dieckmann, Peter Herscovitch, N. Scott Mason, Rolf Swenson, Dale O. Kiesewetter, Keriann M. Backus, Yiqun Geng, Ritu Raj, Daniel C. Anthony, JoAnne L. Flynn, Clifton E. Barry, Benjamin G. Davis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sam
Externí odkaz:
https://doaj.org/article/78179b9a20084b6790bf89a43f40ffbf
Autor:
A. Saidou, A. B. Djafarou, A. A. Alfari, A. Zabeirou Oudou, K. Ide, O. G. Bakou, H. Younssa, L. James Didier, R. Sani
Publikováno v:
BMC Surgery, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Objective To evaluate the surgical management of thyroid pathologies at the Reference General Hospital. Methods This was a retro-prospective study over 4 years 6 months carried out in the departments of General and Digestive Surgery (GDS) an
Externí odkaz:
https://doaj.org/article/af4e3b4513f146528f4aa4bec7bf8963
Autor:
Hong Li, Chi‐Ling Chiang, Kwang Joo Kwak, Xinyu Wang, Sital Doddi, Lakshmi V. Ramanathan, Sun M. Cho, Ya‐Chin Hou, Tai‐Shan Cheng, Xiaokui Mo, Yueh‐Shih Chang, Hui‐Lan Chang, Weiming Cheng, Wei‐Ni Tsai, Luong T. H. Nguyen, Junjie Pan, Yifan Ma, Xilal Y. Rima, Jingjing Zhang, Eduardo Reategui, Yeh‐Shiu Chu, Peter Mu‐Hsin Chang, Pei‐Hung Chang, Chi‐Ying F. Huang, Cheng‐Hsu Wang, Yan‐Shen Shan, Chung‐Pin Li, Martin Fleisher, L. James Lee
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Detecting pancreatic duct adenocarcinoma (PDAC) in its early stages and predicting late‐stage patient prognosis undergoing chemotherapy is challenging. This work shows that the activation of specific oncogenes leads to elevated expression
Externí odkaz:
https://doaj.org/article/a765cae34104438aa7abecd26a692173
Autor:
Chi-Ling Chiang, Yifan Ma, Ya-Chin Hou, Junjie Pan, Sin-Yu Chen, Ming-Hsien Chien, Zhi-Xuan Zhang, Wei-Hsiang Hsu, Xinyu Wang, Jingjing Zhang, Hong Li, Lili Sun, Shannon Fallen, Inyoul Lee, Xing-Yu Chen, Yeh-Shiu Chu, Chi Zhang, Tai-Shan Cheng, Wen Jiang, Betty Y. S. Kim, Eduardo Reategui, Robert Lee, Yuan Yuan, Hsiao-Chun Liu, Kai Wang, Michael Hsiao, Chi-Ying F. Huang, Yan-Shen Shan, Andrew S. Lee, L. James Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) tumours carry multiple gene mutations and respond poorly to treatments. There is currently an unmet need for drug carriers that can deliver multiple gene cargoes to target high solid tumour burden like
Externí odkaz:
https://doaj.org/article/af563ac9db814eeda373f30019d84562
Autor:
Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, DaeYong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R. Schrank, Adam J. Grippin, JongHoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K. Tang, L. James Lee, Andrew S. Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains
Externí odkaz:
https://doaj.org/article/daa7ff6703414ccab6b6c9e5982dab8f
Autor:
Donglin Ding, Alexandra M. Blee, Jianong Zhang, Yunqian Pan, Nicole A. Becker, L. James Maher, Rafael Jimenez, Liguo Wang, Haojie Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Whether TMPRSS2-ERG fusion and TP53 gene alteration coordinately promote prostate cancer (PCa) remains unclear. Here we demonstrate that TMPRSS2-ERG fusion and TP53 mutation / deletion co-occur in PCa patient specimens and this co-occurrence
Externí odkaz:
https://doaj.org/article/397f26f685f14e35b502865eb0a5564e
Autor:
Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Luong T. H. Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, Kim Truc Nguyen, Karunya Albert, Minh‐Dao Duong‐Thi, Nicole Walters, Kwang Joo Kwak, Min Jin Yoon, Hong Li, Jacob Doon‐Ralls, Colin L. Hisey, Daeyong Lee, Yifan Wang, Jonghoon Ha, Kelsey Scherler, Shannon Fallen, Inyoul Lee, Andre F. Palmer, Wen Jiang, Setty M. Magaña, Kai Wang, Betty Y. S. Kim, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of EV bulk biomarker characterization. Herein, we present a
Externí odkaz:
https://doaj.org/article/793a6051126e4fb6a8e9f5fa55384db3
Autor:
Michela Saviana, Giulia Romano, Joseph McElroy, Giovanni Nigita, Rosario Distefano, Robin Toft, Federica Calore, Patricia Le, Daniel Del Valle Morales, Sarah Atmajoana, Stephen Deppen, Kai Wang, L. James Lee, Mario Acunzo, Patrick Nana-Sinkam
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSmall cell lung cancer (SCLC) is characterized by poor prognosis and challenging diagnosis. Screening in high-risk smokers results in a reduction in lung cancer mortality, however, screening efforts are primarily focused on non-small cell
Externí odkaz:
https://doaj.org/article/fde62c5e48d0426982529ada7d2ce1ad
Autor:
A-M. Turner, F. Potjewyd, S. Falcinelli, J. Fox, J. Kirchherr, B. Allard, N. Archin, L. James, D. Margolis
Publikováno v:
Journal of Virus Eradication, Vol 8, Iss , Pp 100128- (2022)
Externí odkaz:
https://doaj.org/article/32f2c0c407cb4005b87c17953641f70d