Zobrazeno 1 - 10
of 17
pro vyhledávání: '"L. J. van 't Veer"'
Autor:
K. Yu, B. Chen, D. Aran, J. Charalel, C. Yau, D. M. Wolf, L. J. van ‘t Veer, A. J. Butte, T. Goldstein, M. Sirota
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Cell lines are used ubiquitously in cancer research but how well they represent the tumor type they were derived from is variable. Here, the authors compare transcriptomic profiles of 22 tumor types and cell lines and propose a new comprehensive cell
Externí odkaz:
https://doaj.org/article/2bd5c7c643b4495ab1808a6fe07e85de
Akademický článek
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Autor:
J M N, Lopes Cardozo, M K, Schmidt, L J, van 't Veer, F, Cardoso, C, Poncet, E J T, Rutgers, C A, Drukker
Publikováno v:
Breast cancer research and treatment. 189(2)
Studies have shown that screen detection by national screening programs is independently associated with better prognosis of breast cancer. The aim of this study is to evaluate the association between tumor biology according to the 70-gene signature
Autor:
L. J. van ’t Veer, E.J.Th. Rutgers, R. R. Patel, F de Snoo, P. Elkhuizen, C.A. Drukker, Peter D. Beitsch, Jelle Wesseling, B. Fowble, P Whitworth, Harry Bartelink, Sjoerd G. Elias, M. V. Nijenhuis
Publikováno v:
Breast cancer research and treatment, 148(3), 599-613. Springer New York
The 70-gene signature (MammaPrint (TM)) has been developed to predict the risk of distant metastases in breast cancer and select those patients who may benefit from adjuvant treatment. Given the strong association between locoregional and distant rec
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 147(9)
Ataxia telangiectasia (AT) is an autosomal recessive disorder characterised by cerebellar ataxia, telangiectasia, immune defects, and a predisposition to malignancy. Chromosomal breakage is a feature. AT cells are abnormally sensitive to cell kill by
Autor:
H, Bartelink, A C, Begg, J C, Martin, M, van Dijk, L, Moonen, L J, van 't Veer, P, Van de Vaart, M, Verheij
Publikováno v:
The cancer journal from Scientific American. 6(1)
The measurement of the effect of cisplatin on DNA has become feasible with the development of antibodies against DNA adducts. In a phase II dose escalation trial with concomitant radiotherapy and daily cisplatin in lung cancer, we found that patients
Publikováno v:
Cancer research. 60(3)
We evaluated the differences in prevalence and functional activity of human estrogen receptor alpha (hER) variant mRNA between 21 normal breast tissues and 41 primary breast carcinomas using a functional assay in yeast for the hER First, we found tha
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 143(7)
A 22-year-old male who had received a kidney transplant from his father (HLA haploidentical), presented with fever and malaise. After transplantectomy was performed because of rejection, the patient developed abdominal pain due to perforation of the
Autor:
A, Broeks, A, de Klein, A N, Floore, M, Muijtjens, W J, Kleijer, N G, Jaspers, L J, van 't Veer
Publikováno v:
Human mutation. 12(5)
Germline mutations in the ATM gene are responsible for the autosomal recessive disorder ataxia-telangiectasia (A-T). In our study, we have determined the ATM mutation spectrum in 19 classical A-T patients, including some immigrant populations, as wel
Autor:
N, Van Zandwijk, L J, Van 't Veer
Publikováno v:
Oncology (Williston Park, N.Y.). 12(1 Suppl 2)
Like other epithelial tumors, non-small-cell lung cancer (NSCLC) is a result of a series of genetic and epigenetic changes that eventually progress to invasive cancer. The order and timing of these changes, involving specific chromosomal locations, o