Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages

Autor: Stephen G. Tristram, L J Williams, Graeme R. Zosky

Publikováno v: International Journal of Environmental Research and Public Health, Vol 18, Iss 146, p 146 (2021)
International Journal of Environmental Research and Public Health
Volume 18
Issue 1

Exposure to geogenic (earth-derived) particulate matter (PM) is linked to severe bacterial infections in Australian Aboriginal communities. Experimental studies have shown that the concentration of iron in geogenic PM is associated with the magnitude

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272048c48be3ee7baf8a562ab2859692
https://www.mdpi.com/1660-4601/18/1/146

Repurposing a fracture risk calculator (FRAX) as a screening tool for women at risk for sarcopenia

Autor: J A, Pasco, M, Mohebbi, M C, Tembo, K L, Holloway-Kew, N K, Hyde, L J, Williams, M A, Kotowicz

Publikováno v: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 31(7)

Osteoporosis and sarcopenia share risk profiles, so we tested a fracture risk assessment tool (FRAX) as a screening tool for sarcopenia. FRAX probabilities without bone mineral density predicted sarcopenia with high sensitivity and reasonable specifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d26c7b67ce68440bfadcc0cb88ae2cfe
https://pubmed.ncbi.nlm.nih.gov/32185435

Inorganic particulate matter modulates non-typeable Haemophilus influenzae growth: a link between chronic bacterial infection and geogenic particles

Autor: L J, Williams, S G, Tristram, G R, Zosky

Publikováno v: Environmental geochemistry and health. 42(7)

Australian Aboriginal populations have unacceptably high rates of bronchiectasis. This disease burden is associated with high rates of detection of pathogenic bacteria, particularly non-typeable Haemophilus influenzae (NTHi). While there is evidence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::299f479636a2acc3468fc559dfbabb6c
https://pubmed.ncbi.nlm.nih.gov/31845018

Measurement of the acute metabolic response to hypoxia in rat tumours in vivo using magnetic resonance spectroscopy and hyperpolarised pyruvate

Autor: Becky A.S. Bibby, Gillian M. Tozer, Tooba Alizadeh, Stephen Metcalf, Emily G. Wholey, Adriana Bucur, Martyn N.J. Paley, L. J. Williams, Samira Kazan, Joanne E. Bluff, Steven Reynolds

Publikováno v: Radiotherapy and Oncology

Purpose To estimate the rate constant for pyruvate to lactate conversion in tumours in response to a hypoxic challenge, using hyperpolarised 13C1-pyruvate and magnetic resonance spectroscopy. Methods and materials Hypoxic inspired gas was used to man

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce0251da7b70d2c2cbc4828996d981a

Anin vivorole for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate

Autor: Debayan Mukherjee, Matthew Fisher, Constantino Carlos Reyes-Aldasoro, Gillian M. Tozer, Simon Akerman, L. J. Williams, Chryso Kanthou

Publikováno v: British Journal of Pharmacology. 171:4902-4913

Background and Purpose Combretastatin A-4 3-O-phosphate (CA4P) is in clinical trial as a tumour vascular disrupting agent (VDA) but the cause of blood flow disruption is unclear. We tested the hypothesis that activation of Rho/Rho kinase (ROCK) is fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::103799e96dc100fa3991b1e62950a8e1
https://doi.org/10.1111/bph.12817