Zobrazeno 1 - 10
of 31
pro vyhledávání: '"L. J. Helman"'
Publikováno v:
Journal of Clinical Investigation. 92:1042-1054
Secretory proteins are targeted into either constitutive (secreted upon synthesis) or regulated (stored in vesicles and released in response to a secretagogue) pathways. To investigate mechanisms of protein targeting into catecholamine storage vesicl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438b0fbb6266290d5478e9cda0441c21
https://doi.org/10.1172/jci116609
https://doi.org/10.1172/jci116609
Autor:
B S, Worley, L T, van den Broeke, T J, Goletz, C D, Pendleton, E M, Daschbach, E K, Thomas, F M, Marincola, L J, Helman, J A, Berzofsky
Publikováno v:
Cancer research. 61(18)
Synovial sarcoma (SS), clear cell sarcoma (CCS), and desmoplastic small round cell tumor (DSRCT) are soft-tissue malignancies occurring primarily in adolescents and young adults. These tumors contain specific chromosomal translocations that fuse the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8889b05038a5565436c2bae03420d180
https://pubmed.ncbi.nlm.nih.gov/11559563
https://pubmed.ncbi.nlm.nih.gov/11559563
Publikováno v:
Cancer research. 60(17)
Our previous expressed sequence tag database analysis indicates that XAGE-1 is frequently found in Ewing's sarcoma and alveolar rhabdomyosarcoma (U. Brinkmann et al., Cancer Res., 59: 1445-1448, 1999). Using Northern blots and RNA dot blots, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a52e89f6e4053af4eeed6f37e0065fa
https://pubmed.ncbi.nlm.nih.gov/10987281
https://pubmed.ncbi.nlm.nih.gov/10987281
Publikováno v:
Medical and pediatric oncology. 34(3)
Various congenital anomalies have been associated with childhood cancer, but as yet no anomaly has been consistently found with Ewing sarcoma (ES). Recently a large case-control study of ES patients reported a greater number of hernias in both cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ace2d9048b59405e7f30a89f412d75f7
https://pubmed.ncbi.nlm.nih.gov/10696126
https://pubmed.ncbi.nlm.nih.gov/10696126
Publikováno v:
Invasionmetastasis. 16(2)
A new human metastatic rhabdomyosarcoma (RMS) model was established and analyzed for a number of biologic, cytogenetic and molecular parameters. Consistent with previous studies, the metastatic capacity of different RMS cell variants did not correlat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f03241c4c49b7f61189058e636df55e9
https://pubmed.ncbi.nlm.nih.gov/9030243
https://pubmed.ncbi.nlm.nih.gov/9030243
Publikováno v:
Oncogene. 11(12)
Insulin-like Growth Factor 2 (IGF2) has recently been demonstrated to be maternally imprinted in both mice and humans. We previously reported loss of imprinting (LOI) of IGF2 in rhabdomyosarcoma (RMS) where IGF2 has been shown to act as an autocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68e04c2355638aca41c4179c2b549e31
https://pubmed.ncbi.nlm.nih.gov/8545106
https://pubmed.ncbi.nlm.nih.gov/8545106
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(3)
The objective of this study was to examine the role of insulin-like growth factor II (IGF-II) in the pathogenesis of human rhabdomyosarcomas (RMS). We have demonstrated previously that RMS express high levels of IGF-II mRNA, secrete IGF-II peptide, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9228d3aea21ca5bb596a6d0f792d26ec
https://pubmed.ncbi.nlm.nih.gov/7794794
https://pubmed.ncbi.nlm.nih.gov/7794794
Publikováno v:
Cancer research. 54(21)
In a previous study, we have shown that insulin-like growth factor type 2 (IGF-2) functions as an autocrine growth factor in human rhabdomyosarcoma (RMS) cell lines. In addition, we demonstrated that the inhibition of binding of IGF-2 to the IGF-1 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40cc14dfebe529f1df6465f018728bd9
https://pubmed.ncbi.nlm.nih.gov/7923191
https://pubmed.ncbi.nlm.nih.gov/7923191
Publikováno v:
Cancer research. 54(10)
Osteogenic sarcoma is the most common bone tumor of childhood and typically occurs during the adolescent growth spurt when growth hormone and insulin-like growth factor I (IGF-I) may be at their lifetime highest levels. Since IGF-I is involved in nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76d7634e75f6ec2be4e455a3ed5bc857
https://pubmed.ncbi.nlm.nih.gov/8168113
https://pubmed.ncbi.nlm.nih.gov/8168113
Publikováno v:
The Journal of biological chemistry. 269(18)
Giardia lamblia, a parasitic protozoan responsible for diarrhea and malabsorption in humans, grows axenically only in media that contain serum and a high concentration of L-cysteine. During our attempts to grow Giardia in the absence of serum, we fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aadbda56eb1a1ce0b2b16ea455b20a5e
https://pubmed.ncbi.nlm.nih.gov/8175729
https://pubmed.ncbi.nlm.nih.gov/8175729