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of 9
pro vyhledávání: '"L. Isabel Cárdenas-Navia"'
Autor:
L Isabel Cárdenas-Navia, Nisc Comparative Sequencing Program, Pedro Cruz, Steven A. Rosenberg, Yardena Samuels, Jimmy Lin
Publikováno v:
Cancer Biology & Therapy. 10:33-37
Heterotrimeric guanine nucleotide-binding proteins (G proteins) mediate signals between G-protein coupled receptors and their downstream pathways, and have been shown to be mutated in cancer. In particular, GNAQ was found to be frequently mutated in
Autor:
Jonathan S. Bromberg, Caius G. Radu, Tuere Wilder, Mark W. Dewhirst, Michail Sitkovsky, L. Isabel Cárdenas-Navia, Bruce N. Cronstein, Troy J. Plumb, Michael L. Dustin, Julie H. Huang, Charles C. Caldwell, Paulo Novis Rocha
Publikováno v:
Scopus-Elsevier
Although the requirements for T lymphocyte homing to lymph nodes (LNs) are well studied, much less is known about the requirements for T lymphocyte locomotion within LNs. Imaging of murine T lymphocyte migration in explanted LNs using two-photon lase
Autor:
Mark W. Dewhirst, Rachel A. Richardson, R. D. Braun, Pierre Sonveaux, Timothy J. McMahon, Andrew M. Kaz, John R. Pawloski, Gillian M. Tozer, Jonathan S. Stamler, Stacey A. Snyder, Joseph Bonaventura, L. Isabel Cárdenas-Navia
Publikováno v:
Circulation Research. 96:1119-1126
In erythrocytes, S -nitrosohemoglobin (SNO-Hb) arises from S -nitrosylation of oxygenated hemoglobin (Hb). It has been shown that SNO-Hb behaves as a nitric oxide (NO) donor at low oxygen tensions. This property, in combination with oxygen transport
Publikováno v:
International journal of radiation oncology, biology, physics. 67(2)
Purpose: To examine the effects of fluctuating oxygen levels on the hypoxic cytotoxin tirapazamine (TPZ) using theoretical predictions. Methods: and Materials Tirapazamine's pharmacokinetic and pharmacodynamic oxygen dependence has previously been ch
Autor:
Timothy W. Secomb, David M. Brizel, Daohai Yu, L. Isabel Cárdenas-Navia, Rod D. Braun, Mark W. Dewhirst
Publikováno v:
Cancer research. 64(17)
The primary purpose of this study was to examine the kinetics of partial pressure of oxygen (pO2) fluctuations in fibrosarcoma (FSA) and 9L tumors under air and O2 breathing conditions. The overall hypothesis was that key factors relating to oxygen t
Publikováno v:
Advances in experimental medicine and biology. 510
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461349648
Tumor hypoxia is known to reduce the sensitivity of tumors to radiation therapy. Although hypoxia plays a major role in tumor response to therapy, its exact causes are still unknown. In particular, the temporal characteristics of acute hypoxia have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9329e2b5e76c2a0c9672c3c0899e91a4
https://doi.org/10.1007/978-1-4615-0205-0_2
https://doi.org/10.1007/978-1-4615-0205-0_2
Publikováno v:
Frontiers in Bioscience. 12:4061
Tumor hypoxia is a serious and enduring problem for traditional solid tumor therapies. Many scientists continue to explore methods to improve or exploit tumor oxygenation; more recently, scientists have also focused on altering the molecular effects
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