Zobrazeno 1 - 10 of 22 pro vyhledávání: '"L. I. Kolobushkina"'
1
Nonglycoside analogs of nucleotides
Autor: V. L. Florent'ev, S. N. Mikhailov, L. I. Kolobushkina, A. M. Kritsyn
Publikováno v: Chemistry of Heterocyclic Compounds. 11:108-113
N1-(2′,3′-Dihydroxypropyl)uracil, -thymine, -cytosine, and N9-(2′,3′-dihydroxypropyl)adenine were synthesized by alkylation of nucleic bases with 2,3-O-isopropylideneglycerol chlorohydrin, subsequent separation of the resulting mixtures, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0899d73de4a83f39ca36f2a189b5c221
https://doi.org/10.1007/bf00945286
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2
Use of 5-deoxy-ribo-hexofuranose derivatives for the preparation of 5'-nucleotide phosphonates and homoribonucleosides
Autor: L. I. Kolobushkina, Nelly Sh. Padyukova, S. N. Mikhailov, Leon N. Beigelman, Marat Ya. Karpeiskii
Publikováno v: Collection of Czechoslovak Chemical Communications. 54:1055-1066
A convenient and general method is proposed for the synthesis of 5'-nucleotide phosphonate analogs starting from 5-deoxy-1,2-O-isopropylidene-α-D-xylo-hexofuranose which can easily be produced in preparative quantities from D-glucose. Phosphonate II
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e95436bb20d82bedee0b4eab1dfc0198
https://doi.org/10.1135/cccc19891055
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4
Vitamin b6 analogs
Autor: N. I. Spiridonova, L. I. Kolobushkina, V. L. Florent'ev
Publikováno v: Chemistry of Heterocyclic Compounds. 10:567-571
4-Acetyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine 5-phosphate (IV) was synthesized by oxidation of 3-hydroxy-5-hydroxymethyl-4-(α-hydroxyethyl)-2-methylpyridine 5-phosphate (III) with chromic anhydride. Compound III was obtained by phosphorylation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::172e5957d33a71f59ffaef7e0f4a17df
https://doi.org/10.1007/bf00471329
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5
A new scheme for the synthesis of 5′-nucleotide phosphonate analogs
Autor: Sergey N. Mikhailov, Marat Ya. Karpeisky, Nelly Sh. Padyukova, L. I. Kolobushkina
Publikováno v: Tetrahedron Letters. 28:3623-3626
A convenient and general method is proposed for the synthesis of 5'-nucleotide phosphonate analogs starting from 5-deoxy-1,2-O-isopropylidene-alpha-D-xylo-hexofuranose.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1217ebd1fdf6d7c2b7dadf0712880fda
https://doi.org/10.1016/s0040-4039(00)95552-7
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6
Nonglycoside analogs of nucleotides Communication 6. Mono- and triphosphates of ?-hydroxyalkyl derivatives of nucleic bases
Autor: N. Sh. Padyukova, V. L. Florent'ev, A. M. Kritsyn, S. M. Mikhailov, L. I. Kolobushkina
Publikováno v: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 24:1728-1732
1. A comparative study was made of various methods for the phosphorylation of the Ω-hydroxyalkyl derivatives of nucleic bases. A convenient method was developed for preparing the nucleotide analogs 2. The nonglycoside analogs of the adenosine and ur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd7129ba66f8b027863fdeb9bba71e51
https://doi.org/10.1007/bf01100030
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8
Synthesis of 4-thiouridine derivatives
Autor: L. I. Kolobushkina, A. M. Kritsyn, V. L. Florent'ev
Publikováno v: Chemistry of Heterocyclic Compounds. 9:917-921
The thionation of a protected uridine with the aid of P2S5 has given the corresponding 4-thiouridine derivatives, which have been phosphorylated at the 5′ or the 2′(3′)hydroxyl. On being heated in aqueous pyridine solution with liquid hydrogen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03053a2ae288f086d4dce6454abe070c
https://doi.org/10.1007/bf00471583
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