Zobrazeno 1 - 10
of 2 212
pro vyhledávání: '"L. Hull"'
Autor:
Sina A. Gharib, Rachna Vemireddy, Joseph J. Castillo, Brendy S. Fountaine, Theo K. Bammler, James W. MacDonald, Rebecca L. Hull-Meichle, Sakeneh Zraika
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Insulin secretion is impaired in individuals with cystic fibrosis (CF), contributing to high rates of CF-related diabetes (CFRD) and substantially increasing disease burden. To develop improved therapies for CFRD, better knowledge of pancrea
Externí odkaz:
https://doaj.org/article/02eecb3558cb4daeb1a5360a32a28b02
Autor:
Vanessa L. Hull, Yan Wang, Jennifer McDonough, Meina Zhu, Travis Burns, Najmah Al Ramel, Ali Dehghani, Fuzheng Guo, David Pleasure
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 1059-1062 (2024)
Abstract Canavan disease is a leukodystrophy caused by ASPA mutations that diminish oligodendroglial aspartoacylase activity, and is characterized by markedly elevated brain concentrations of the aspartoacylase substrate N‐acetyl‐l‐aspartate (N
Externí odkaz:
https://doaj.org/article/eeb55501af2040ab83c03837d9466fbf
Autor:
James O Burton, Jennifer Kent, Katherine L Hull, Sophie Pittaway, Jemma Reast, Catherine Clair, Mandeep Moore, Pete Revell
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Objective Chronic kidney disease (CKD)-associated anaemia has substantial biopsychosocial impacts. This study explores the impact of CKD-associated anaemia and treatment preferences from the patient perspective.Design Cross-sectional survey.Setting A
Externí odkaz:
https://doaj.org/article/3e6c5d0494554e2885ba2ecd125d3940
Autor:
Nadine Nagy, Kathryn S. Czepiel, Gernot Kaber, Darko Stefanovski, Aviv Hargil, Nina Pennetzdorfer, Robert Targ, Saranya C. Reghupaty, Thomas N. Wight, Robert B. Vernon, Rebecca L. Hull-Meichle, Payton Marshall, Carlos O. Medina, Hunter Martinez, Anissa Kalinowski, Rudolph D. Paladini, Stavros Garantziotis, Joshua W. Knowles, Paul L. Bollyky
Publikováno v:
Cells, Vol 13, Iss 20, p 1727 (2024)
Given that the extracellular matrix polymer hyaluronan (HA) has been implicated in longevity, we asked whether 4-methylumbelliferone (4-MU), an inhibitor of HA synthesis, impacts lifespan in mice. We designed a prospective study of long-term administ
Externí odkaz:
https://doaj.org/article/da7d8866843c4dd994d1c93481a81662
Publikováno v:
Bioengineering, Vol 11, Iss 9, p 910 (2024)
Current surgical practices in total knee arthroplasty (TKA) have advanced and include significant changes and improvements in alignment philosophies, femorotibial implant conformities, and ligament management to replicate in vivo knee kinematics. Whi
Externí odkaz:
https://doaj.org/article/1a402151aca2424e8c8b7464bf537fd9
Autor:
Katherine L. Hull, Kate Bramham, Cassandra L. Brookes, Victoria Cluley, Carmel Conefrey, Nicola J. Cooper, Helen Eborall, James Fotheringham, Matthew P. M. Graham-Brown, Laura J. Gray, Patrick B. Mark, Sandip Mitra, Gavin J. Murphy, Niamh Quann, Leila Rooshenas, Madeleine Warren, James O. Burton
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background In-centre nocturnal haemodialysis (INHD) offers extended-hours haemodialysis, 6 to 8 h thrice-weekly overnight, with the support of dialysis specialist nurses. There is increasing observational data demonstrating potential benefit
Externí odkaz:
https://doaj.org/article/27461e02c4a6408ea9b86d8cf9ae29b4
Autor:
Bharat Sidhu, Akash Mavilakandy, Katherine L. Hull, Ivelin Koev, Zakariyya Vali, James O. Burton, G. André Ng
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 25, Iss 4, p 143 (2024)
Chronic kidney disease (CKD) and atrial fibrillation (AF) are associated with significant cardiovascular morbidity and mortality. Recent studies have highlighted an increased prevalence and incidence of AF in patients with CKD. This article aims to p
Externí odkaz:
https://doaj.org/article/b73a2e73b1cd4847ad3397f3990c0313
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Cystic fibrosis (CF) is a multi-organ disease caused by loss-of-function mutations in CFTR (which encodes the CF transmembrane conductance regulator ion channel). Cystic fibrosis related diabetes (CFRD) occurs in 40-50% of adults with CF and is assoc
Externí odkaz:
https://doaj.org/article/0b938453eae94ecda480ced02c4cc63f
Autor:
Cletus L. Hull III
The cross of Christ crucified symbolized the central theme of Paul's ministry. In his letter to the Corinthians, the apostle commenced his correspondence with the message about the cross and power of God (1 Cor 1:18, NRSV). The proposal for this pape
Publikováno v:
Bioengineering, Vol 11, Iss 1, p 62 (2024)
Because kinematic alignment (KA) aligns femoral components in greater valgus and with less external rotation than mechanical alignment (MA), the trochlear groove of an MA design used in KA is medialized, which can lead to complications. Hence, a KA d
Externí odkaz:
https://doaj.org/article/54805da7671144e196f566a1497c5f4b