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Autor:
S. Augustin, Anusch Peyman, D. W. Will, M. Helsberg, L. Ötvös, Janos Sagi, E. Uhlmann, L. Homung, Shawn D. Mustain, Joshua O. Ojwang, S. Hein, Robert F. Rando
Publikováno v:
Nucleosides and Nucleotides. 16:1717-1720
Antisense oligonucleotides directed against HSV- 1 immediate early gene mRNA were synthesized with replacement of the internal pyrimidine nucleotides by the corresponding 5-(l-hexynyl) analogues and with end-capping by phosphorothioates. These compou