Zobrazeno 1 - 10
of 3 121
pro vyhledávání: '"L. Holmes"'
Publikováno v:
Audiology Research, Vol 14, Iss 3, Pp 545-553 (2024)
The COVID-19 pandemic dramatically changed health service delivery with vulnerable patients advised to isolate and appointments provided virtually. This change affected recruitment into an observational cohort study, undertaken at a single site, wher
Externí odkaz:
https://doaj.org/article/f0adf038b66447239e8e1ac46441c9be
Autor:
Harry L T Mobley, Mark T Anderson, Bridget S Moricz, Geoffrey B Severin, Caitlyn L Holmes, Elizabeth N Ottosen, Tad Eichler, Surbhi Gupta, Santosh Paudel, Ritam Sinha, Sophia Mason, Stephanie D Himpsl, Aric N Brown, Margaret Gaca, Christina M Kiser, Thomas H Clarke, Derrick E Fouts, Victor J DiRita, Michael A Bachman
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012495 (2024)
There is a critical gap in knowledge about how Gram-negative bacterial pathogens, using survival strategies developed for other niches, cause lethal bacteremia. Facultative anaerobic species of the Enterobacterales order are the most common cause of
Externí odkaz:
https://doaj.org/article/790cb40716724b9980c96102427a6fde
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAnti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis, but the sources of citrullinated antigens as well as which peptidylarginine deiminases (PADs) are required for their production remain incompletely defi
Externí odkaz:
https://doaj.org/article/775a57052f284fc39ce1d8353ef9387b
Autor:
Aviana O Rosen, Maria Dolores Hidalgo, Colleen B Mistler, Nekane Balluerka, Arantxa Gorostiaga, Juana Gómez-Benito, Ashley L Holmes, Tania B Huedo-Medina
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 7, p e0003389 (2024)
The COVID-19 pandemic had a detrimental effect on mental health since its start in 2020 and current data on mental health is limited. This study provides recent longitudinal data on psychological distress among a country-wide sample of adults. We rec
Externí odkaz:
https://doaj.org/article/45cfe77946374253ba9ca10d165d9af0
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes
Autor:
Benjamin B. Johnson, Marie-Victoire Cosson, Lorenza I. Tsansizi, Terri L. Holmes, Tegan Gilmore, Katherine Hampton, Ok-Ryul Song, Nguyen T.N. Vo, Aishah Nasir, Alzbeta Chabronova, Chris Denning, Mandy J. Peffers, Catherine L.R. Merry, John Whitelock, Linda Troeberg, Stuart A. Rushworth, Andreia S. Bernardo, James G.W. Smith
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113668- (2024)
Summary: Perlecan (HSPG2), a heparan sulfate proteoglycan similar to agrin, is key for extracellular matrix (ECM) maturation and stabilization. Although crucial for cardiac development, its role remains elusive. We show that perlecan expression incre
Externí odkaz:
https://doaj.org/article/0c05f13bcfee4a91beacd41b215a3bd4
Autor:
Caitlyn L. Holmes
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTCaitlyn Holmes works in the field of bacterial pathogenesis and host-pathogen interactions. In this mSphere of Influence article, she reflects on how the papers “Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella pneumoniae Cle
Externí odkaz:
https://doaj.org/article/799fbcfdf2c64e2391336e2ea2473a51
Autor:
Jay Vornhagen, Emily K. Roberts, Lavinia Unverdorben, Sophia Mason, Alieysa Patel, Ryan Crawford, Caitlyn L. Holmes, Yuang Sun, Alexandra Teodorescu, Evan S. Snitkin, Lili Zhao, Patricia J. Simner, Pranita D. Tamma, Krishna Rao, Keith S. Kaye, Michael A. Bachman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Patient variables, such as comorbidities, partially explain which patients will progress to Klebsiella infection, with colonization of the gut acting as a reservoir. Little is known, however, regarding Klebsiella genes that may increase risk of disea
Externí odkaz:
https://doaj.org/article/9fca71bb880145e79855025ffb4001fa
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011385 (2023)
Kaposi's Sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's Sarcoma (KS), a highly vascularized tumor common in AIDS patients and many countries in Africa. KSHV is predominantly in the latent state in the main KS tumor cell, the spindle ce
Externí odkaz:
https://doaj.org/article/eca2e9f009904eec926b006ad60ef7a2
Autor:
Francisco Velasquez, Conor Dickson, Michelle L. Kloc, Carmel A. Schneur, Jeremy M. Barry, Gregory L. Holmes
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 106021- (2023)
There is increasing human and animal evidence that brain oscillations play a critical role in the development of spatial cognition. In rat pups, disruption of hippocampal rhythms via optogenetic stimulation during the critical period for memory devel
Externí odkaz:
https://doaj.org/article/d93fc8b0b7444bcd84d0262066b6377b
Autor:
Mohammad Hosseini, Catherine A Gao, David M Liebovitz, Alexandre M Carvalho, Faraz S Ahmad, Yuan Luo, Ngan MacDonald, Kristi L Holmes, Abel Kho
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292216 (2023)
ObjectiveChatGPT is the first large language model (LLM) to reach a large, mainstream audience. Its rapid adoption and exploration by the population at large has sparked a wide range of discussions regarding its acceptable and optimal integration in
Externí odkaz:
https://doaj.org/article/8708e71be89e4b11b2ae1a56acd5f763