Zobrazeno 1 - 10
of 125
pro vyhledávání: '"L. Hillestad"'
Autor:
D. Kent Arrell, Ruben J. Crespo‐Diaz, Satsuki Yamada, Ryounghoon Jeon, Armin Garmany, Sungjo Park, Jeffrey P. Adolf, Christopher Livia, Matthew L. Hillestad, Jozef Bartunek, Atta Behfar, Andre Terzic
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 9, Pp 1320-1328 (2021)
Abstract Stem cell paracrine activity is implicated in cardiac repair. Linkage between secretome functionality and therapeutic outcome was here interrogated by systems analytics of biobanked human cardiopoietic cells, a regenerative biologic in advan
Externí odkaz:
https://doaj.org/article/75bc9f6f0ba34a4fa317130e08442ad7
Autor:
Ruben J. Crespo-Diaz, Atta Behfar, Sungjo Park, Jozef Bartunek, Satsuki Yamada, Ryoung-Hoon Jeon, Jeffrey P. Adolf, Matthew L. Hillestad, Armin Garmany, Andre Terzic, Christopher Livia, D. Kent Arrell
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 9, Pp 1320-1328 (2021)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Stem cell paracrine activity is implicated in cardiac repair. Linkage between secretome functionality and therapeutic outcome was here interrogated by systems analytics of biobanked human cardiopoietic cells, a regenerative biologic in advanced clini
Autor:
Andre Terzic, Ryoung-Hoon Jeon, Tyra A. Witt, Jonathan J. Nesbitt, Raman Deep Singh, Mukesh K. Pandey, Soulmaz Boroumand, Ruben J. Crespo-Diaz, Ribu Goyal, Mark Li, Tina M. Gunderson, Matthew L. Hillestad, Atta Behfar, Timothy R. DeGrado, Aditya Bansal, Nicholas R. Schmit, Satsuki Yamada
Publikováno v:
Nuclear Medicine and Biology. :23-30
Introduction Radiolabeling of stem cells with a positron emitting radioisotope represents a major advancement in regenerative biotherapy enabling non-invasive imaging. To assess the value of such an approach in a clinically relevant scenario, the tol
Autor:
Anthony J. Croatt, Michael A. Barry, John D. Belcher, Gregory M. Vercellotti, Matthew L. Hillestad, Vesna D. Garovic, Karl A. Nath, Joseph P. Grande, Raymond F. Regan, Meryl C. Nath
Publikováno v:
Am J Physiol Heart Circ Physiol
In the murine venous thrombosis model induced by ligation of the inferior vena cava (IVCL), genetic deficiency of heme oxygenase-1 (HO-1) increases clot size. This study examined whether induction of HO-1 or administration of its products reduces thr
Autor:
Alexey E. Alekseev, Mark Li, Christopher Livia, Satsuki Yamada, Matthew L. Hillestad, Atta Behfar, Paul G. Stalboerger, Andre Terzic, Tyra A. Witt, Raman Deep Singh
Publikováno v:
Tissue Engineering Part A. 25:145-158
Myocardial infarction occurs every 36 s or nearly 1 million times in the United States. The treatment of acute myocardial infarction (AMI) has been revolutionized with coronary reperfusion ensuring...
Autor:
Karl A. Nath, Matthew L. Hillestad, Joseph P. Grande, Anthony J. Croatt, Lu Kang, Zvonimir S. Katusic, Michael A. Barry
Publikováno v:
American Journal of Physiology-Renal Physiology. 310:F466-F476
The arteriovenous fistula (AVF) is the preferred hemodialysis vascular access, but it is complicated by high failure rates and attendant morbidity. This study provides the first description of a murine AVF model that recapitulates two salient feature
Autor:
Raman Deep, Singh, Matthew L, Hillestad, Christopher, Livia, Mark, Li, Alexey E, Alekseev, Tyra A, Witt, Paul G, Stalboerger, Satsuki, Yamada, Andre, Terzic, Atta, Behfar
Publikováno v:
Tissue engineering. Part A. 25(1-2)
Myocardial infarction occurs every 36 s or nearly 1 million times in the United States. The treatment of acute myocardial infarction (AMI) has been revolutionized with coronary reperfusion ensuring over 96% in-hospital survival. There has, however, b
Autor:
Michael A. Barry, Anthony J. Croatt, Matthew L. Hillestad, Karl A. Nath, Zvonimir S. Katusic, Lu Kang, Gianrico Farrugia, Joseph P. Grande
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 308:H1402-H1413
The present study examined the heme oxygenase (HO) system in an in vivo murine model of pathological shear stress induced by partial carotid artery ligation. In this model, along with upregulation of vasculopathic genes, HO-1 is induced in the endoth
Autor:
Mary E. Barry, Sean E. Hofherr, Matthew L. Hillestad, Eric A. Weaver, Sarah Venezia, Jan P. Kraus, Dietrich Matern, Michael A. Barry, Adam J. Guenzel
Publikováno v:
Molecular Therapy. 21:1316-1323
Propionic acidemia (PA) is a recessive genetic disease that results in an inability to metabolize certain amino acids and odd-chain fatty acids. Current treatment involves restricting consumption of these substrates or liver transplantation. Deletion
Publikováno v:
Journal of Virology. 87:3678-3686
Adenovirus serotype 5 (Ad5) naturally infects the liver after intravenous injection, making it a candidate for hepatocyte-directed gene transfer. While Ad5 can be efficient, most of the dose is destroyed by liver Kupffer cells before it can reach hep