Zobrazeno 1 - 10
of 323
pro vyhledávání: '"L. Heuchel"'
Autor:
Carlos Fernández Moro, Natalie Geyer, Sara Harrizi, Yousra Hamidi, Sara Söderqvist, Danyil Kuznyecov, Evelina Tidholm Qvist, Media Salmonson Schaad, Laura Hermann, Amanda Lindberg, Rainer L. Heuchel, Alfonso Martín-Bernabé, Soniya Dhanjal, Anna C. Navis, Christina Villard, Andrea C. del Valle, Lorand Bozóky, Ernesto Sparrelid, Luc Dirix, Carina Strell, Arne Östman, Bernhard Schmierer, Peter B. Vermeulen, Jennie Engstrand, Béla Bozóky, Marco Gerling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with colorectal cancer live
Externí odkaz:
https://doaj.org/article/1e0e733410a64db5b9017544b7a2ff5f
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/4077c569e2734ec8b241f86bf508a044
Autor:
Benedek Bozóky, Carlos Fernández Moro, Carina Strell, Natalie Geyer, Rainer L. Heuchel, J. Matthias Löhr, Ingemar Ernberg, Laszlo Szekely, Marco Gerling, Béla Bozóky
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1300-1306 (2021)
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid tumors. Based on transcriptomic classifiers, basal-like and classical PDAC subtypes have been defined that differ in prognosis. Cells of both subtypes can coexi
Externí odkaz:
https://doaj.org/article/91e8e2b3c7e24a6e950edafe3ff950a1
Autor:
K. J. Norberg, X. Liu, C. Fernández Moro, C. Strell, S. Nania, M. Blümel, A. Balboni, B. Bozóky, R. L. Heuchel, J. M. Löhr
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Pancreatic ductal adenocarcinoma is a devastating disease with poor outcome, generally characterized by an excessive stroma component. The purpose of this study was to develop a simple and reproducible in vitro 3D-assay employing
Externí odkaz:
https://doaj.org/article/c855627a1d764404bdb707e7311e8031
Publikováno v:
Pancreas. 50:1427-1434
Transforming growth factor-β (TGF-β)-mediated accumulation of extracellular matrix proteins such as collagen I is a common feature of fibrosis. Pancreatic stellate cells play an integral role in the pathogenesis of pancreatitis, and their profibrot
Autor:
Marvin Schober, Ralf Jesenofsky, Ralf Faissner, Cornelius Weidenauer, Wolfgang Hagmann, Patrick Michl, Rainer L. Heuchel, Stephan L. Haas, J.-Matthias Löhr
Publikováno v:
Cancers, Vol 6, Iss 4, Pp 2137-2154 (2014)
Pancreatic ductal adenocarcinoma (PDAC) occurs mainly in people older than 50 years of age. Although great strides have been taken in treating PDAC over the past decades its incidence nearly equals its mortality rate and it was quoted as the 4th lead
Externí odkaz:
https://doaj.org/article/81e7e7ed8af4438caf8b34b03d0ab657
Autor:
C. Hahn, L. Heuchel, J. Ödén, J. Wulff, S. Plaude, B. Timmermann, C. Bäumer, E. Traneus, A. Lühr
Publikováno v:
Radiotherapy and Oncology. 170:S1531-S1532
Akademický článek
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Publikováno v:
Radiotherapy and Oncology. 161:S313-S314
Autor:
Guan-Xian Liu, You-Qi Li, Xiao R Huang, Lihua Wei, Hai-Yong Chen, Yong-Jun Shi, Rainer L Heuchel, Hui Y Lan
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53573 (2013)
Smad7 is an inhibitory Smad and plays a protective role in obstructive and diabetic kidney disease. However, the role and mechanisms of Smad7 in hypertensive nephropathy remains unexplored. Thus, the aim of this study was to investigate the role and
Externí odkaz:
https://doaj.org/article/767a84863a7144b897f0843fc5ff7a4f