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Akademický článek

The effects of iron deficient and high iron diets on SARS-CoV-2 lung infection and disease

Autor: Agnes Carolin, David Frazer, Kexin Yan, Cameron R. Bishop, Bing Tang, Wilson Nguyen, Sheridan L. Helman, Jay Horvat, Thibaut Larcher, Daniel J. Rawle, Andreas Suhrbier

Publikováno v: Frontiers in Microbiology, Vol 15 (2024)

IntroductionThe severity of Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is often dictated by a range of comorbidities. A considerable literature suggests iron deficiency and iron over

Externí odkaz: https://doaj.org/article/290d3d8be95a4ccda3ce6f0c5dc5c3ca

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Novel treatment for hypotonic airway obstruction and severe obstructive sleep apnea using a nasopharyngeal airway device with 3D printing innovation

Autor: Allison R, Powell, Sudharsan, Srinivasan, Jennifer L, Helman, Annie Dian-Ru, Li, Louise M, O'Brien, Albert, Shih, Jeff S, Plott, David A, Zopf

Publikováno v: Journal of Clinical Sleep Medicine. 18:2497-2502

Pediatric obstructive sleep apnea impacts child and familial well-being. Airway management in patients with hypotonic pharyngeal conditions is complex. Some patients may benefit from continuous positive airway pressure or bilevel positive airway pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84afc50d54b911887aa6e28f06bf0ece
https://doi.org/10.5664/jcsm.10202

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The biology of mammalian multi-copper ferroxidases

Autor: Sheridan L. Helman, Jie Zhou, Brie K. Fuqua, Yan Lu, James F. Collins, Huijun Chen, Christopher D. Vulpe, Gregory J. Anderson, David M. Frazer

Publikováno v: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, vol 36, iss 2
Biometals

The mammalian multicopper ferroxidases (MCFs) ceruloplasmin (CP), hephaestin (HEPH) and zyklopen (ZP) comprise a family of conserved enzymes that are essential for body iron homeostasis. Each of these enzymes contains six biosynthetically incorporate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b61329225401e190bc038d5c2214ce
https://escholarship.org/uc/item/35n736xd

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A Novel Ferritin-Core Analog Is a Safe and Effective Alternative to Oral Ferrous Iron for Treating Iron Deficiency during Pregnancy in Mice

Autor: Gregory J. Anderson, Sarah J. Wilkins, Daniel R. McKeating, Nuno Faria, Jonathan J. Powell, Anthony V. Perkins, Sheridan L. Helman, David M. Frazer, James S. M. Cuffe, Gunter Hartel

Publikováno v: The Journal of Nutrition. 152:714-722

BACKGROUND: Many women enter pregnancy with iron stores that are insufficient to maintain maternal iron balance and support fetal development and, consequently, often require iron supplements. However, the side effects associated with many currently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8a1892150afc52be1c05ae446e1e28a
https://doi.org/10.1093/jn/nxab363

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Akademický článek

Circulating iron levels influence the regulation of hepcidin following stimulated erythropoiesis

Autor: Cornel S.G. Mirciov, Sarah J. Wilkins, Grace C. C. Hung, Sheridan L. Helman, Gregory J. Anderson, David M. Frazer

Publikováno v: Haematologica, Vol 103, Iss 10 (2018)

The stimulation of erythrocyte formation increases the demand for iron by the bone marrow and this in turn may affect the levels of circulating diferric transferrin. As this molecule influences the production of the iron regulatory hormone hepcidin,

Externí odkaz: https://doaj.org/article/1b11bd582f8140b091bbcf927056e14b

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The Placental Ferroxidase Zyklopen Is Not Essential for Iron Transport to the Fetus in Mice

Autor: Gregory J. Anderson, Daniel F. Wallace, Elise S. Pelzer, Brie K. Fuqua, Chris D. Vulpe, Sheridan L. Helman, David M. Frazer, Sarah J. Wilkins, Anthony V. Perkins, Page E Whibley, David G. Simmons, Jessica L. O’Callaghan, James S. M. Cuffe, Daniel R. McKeating

Publikováno v: The Journal of Nutrition. 151:2541-2550

BACKGROUND: The ferroxidase zyklopen (Zp) has been implicated in the placental transfer of iron to the fetus. However, the evidence for this is largely circumstantial. OBJECTIVES: This study aimed to determine whether Zp is essential for placental ir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5600556b964f8c239039c41aef5615cd
https://doi.org/10.1093/jn/nxab174

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Clues: Using Generative Strategies to Improve the Science Vocabulary of Secondary English Learners With Reading Disabilities

Autor: Minyi Shih Dennis, Amanda L. Helman, Lee Kern

Publikováno v: Learning Disability Quarterly. 45:19-31

English learners (ELs) with reading disabilities (RDs) have been among the lowest performers on academic achievement tests that assess vocabulary. To meet academic demands and prepare for college or careers, ELs with RDs clearly need support in terms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7d689a0aa08527c6387e1469a82be88
https://doi.org/10.1177/0731948720929005

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