Zobrazeno 1 - 10
of 408
pro vyhledávání: '"L. Hann"'
Autor:
Kai-li Liang, Sean Tackett, Samantha Myers, Julie R. Brahmer, Ilene S. Browner, David S. Ettinger, Patrick M. Forde, Russell K. Hales, Christine L. Hann, Vincent K. Lam, Kristen A. Marrone, Tricia Patel, Valerie Peterson, Sarah Sagorsky, Michelle Turner, Khinh R. Voong, Jarushka Naidoo, Josephine L. Feliciano
Publikováno v:
Current Oncology, Vol 29, Iss 6, Pp 4342-4353 (2022)
Introduction: With the increasing use of immune checkpoint inhibitors (ICI) for cancer, there is a growing burden on the healthcare system to provide care for the toxicities associated with these agents. Herein, we aim to identify and describe the di
Externí odkaz:
https://doaj.org/article/e7755653efc74e219febc8c1c7997306
Autor:
Aaron S. Mansfield, David S. Hong, Christine L. Hann, Anna F. Farago, Himisha Beltran, Saiama N. Waqar, Andrew E. Hendifar, Lowell B. Anthony, Matthew H. Taylor, Alan H. Bryce, Scott T. Tagawa, Karl Lewis, Jiaxin Niu, Christine H. Chung, James M. Cleary, Michael Rossi, Carrianne Ludwig, Ricardo Valenzuela, Yan Luo, Rahul Aggarwal
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-7 (2021)
Abstract Delta-like protein 3 (DLL3) is highly expressed in solid tumors, including neuroendocrine carcinomas/neuroendocrine tumors (NEC/NET). Rovalpituzumab tesirine (Rova-T) is a DLL3-targeting antibody-drug conjugate. Patients with NECs and other
Externí odkaz:
https://doaj.org/article/41cea5032a0d44ac9ceef9a9bed44b7a
Autor:
Susan C. Scott, Xiaoshan M. Shao, Noushin Niknafs, Archana Balan, Gavin Pereira, Kristen A. Marrone, Vincent K. Lam, Joseph C. Murray, Josephine L. Feliciano, Benjamin P. Levy, David S. Ettinger, Christine L. Hann, Julie R. Brahmer, Patrick M. Forde, Rachel Karchin, Jarushka Naidoo, Valsamo Anagnostou
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe magnitude of response to immune checkpoint inhibitor (ICI) therapy may be sex-dependent, as females have lower response rates and decreased survival after ICI monotherapy. The mechanisms underlying this sex dimorphism in ICI response
Externí odkaz:
https://doaj.org/article/2f91c0b2890647729b3fe999f6a97a89
Autor:
Joshua E. Reuss, MD, Emily Brigham, MD, MHS, Kevin J. Psoter, PhD, Khinh Ranh Voong, MD, Bairavi Shankar, BS, David S. Ettinger, MD, Kristen A. Marrone, MD, Christine L. Hann, MD, Benjamin Levy, MD, Josephine L. Feliciano, MD, Julie R. Brahmer, MD, David Feller-Kopman, MD, Andrew D. Lerner, MD, Hans Lee, MD, Lonny Yarmus, DO, Russell K. Hales, MD, Franco D’Alessio, MD, Sonye K. Danoff, MD, PhD, Patrick M. Forde, MBBCH, Karthik Suresh, MD, Jarushka Naidoo, MBBCH, MHS
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 10, Pp 100220- (2021)
Introduction: Checkpoint inhibitor pneumonitis (CIP) is a serious toxicity of anti–programmed death-(ligand) 1 immunotherapy. Whether pretreatment differences in pulmonary function exist in patients who develop CIP is unknown. We analyzed the pulmo
Externí odkaz:
https://doaj.org/article/d916673ba4b249d5ba179b35fe488531
Autor:
Lavanya Sivapalan, Wade T. Iams, Zineb Belcaid, Susan C. Scott, Noushin Niknafs, Archana Balan, James R. White, Prasad Kopparapu, Christopher Cann, Blair V. Landon, Gavin Pereira, Victor E. Velculescu, Christine L. Hann, Christine M. Lovly, Valsamo Anagnostou
Publikováno v:
Clinical Cancer Research. :OF1-OF14
Purpose: Patients with small-cell lung cancer (SCLC) have an exceptionally poor prognosis, calling for improved real-time noninvasive biomarkers of therapeutic response. Experimental Design: We performed targeted error-correction sequencing on 171 se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513e58885b12014079a0fd6aed4019ec
https://doi.org/10.1158/1078-0432.ccr-22-2242
https://doi.org/10.1158/1078-0432.ccr-22-2242
Autor:
Xing Wang, Natasha Raman, Ghali Lemtiri-Chlieh, Jinhee Chang, Shreya Jagtap, Dipanwita Dutta Chowdhury, Matthew Ballew, Francesca Anna Carrieri, Triet Nguyen, Katriana Nugent, Travis Peck, Michelle S. Levine, Aaron Chan, Christine Lam, Reem Malek, Tung Hoang, Ryan Phillips, ZhuoAn Cheng, Kekoa Taparra, Nick Connis, Christine L. Hann, Andrew Holland, Phuoc T. Tran, Audrey Lafargue, Hailun Wang
Publikováno v:
Molecular Cancer Therapeutics. 22:519-528
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c109ad13608c562d8b330269ae2aa510
https://doi.org/10.1158/1535-7163.mct-22-0191
https://doi.org/10.1158/1535-7163.mct-22-0191
Autor:
Gary L. Gallia, Ming Zhang, Yi Ning, Michael C. Haffner, Denise Batista, Zev A. Binder, Justin A. Bishop, Christine L. Hann, Ralph H. Hruban, Masaru Ishii, Alison P. Klein, Douglas D. Reh, Lisa M. Rooper, Vafi Salmasi, Rafael J. Tamargo, Qing Wang, Tara Williamson, Tianna Zhao, Ying Zou, Alan K. Meeker, Nishant Agrawal, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Chetan Bettegowda
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
Olfactory neuroblastoma (ONB) is a rare malignant tumor whose genetic basis is poorly understood. Here the authors identify recurrent deletions involving dystrophin in the majority of ONB patient tumors examined.
Externí odkaz:
https://doaj.org/article/666203899eb144b58109b82017f4bbe7
Autor:
Noushin Niknafs, Archana Balan, Christopher Cherry, Karlijn Hummelink, Kim Monkhorst, Xiaoshan M. Shao, Zineb Belcaid, Kristen A. Marrone, Joseph Murray, Kellie N. Smith, Benjamin Levy, Josephine Feliciano, Christine L. Hann, Vincent Lam, Drew M. Pardoll, Rachel Karchin, Tanguy Y. Seiwert, Julie R. Brahmer, Patrick M. Forde, Victor E. Velculescu, Valsamo Anagnostou
Publikováno v:
Nature Medicine. 29:440-449
Tumor mutation burden is an imperfect proxy of tumor foreignness and has therefore failed to consistently demonstrate clinical utility in predicting responses in the context of immunotherapy. We evaluated mutations in regions of the genome that are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c09aa02ded7b6871f42cf4e48e9f1c
https://doi.org/10.1038/s41591-022-02163-w
https://doi.org/10.1038/s41591-022-02163-w
Autor:
Man-Fung Yuen, Kosh Agarwal, Xiaoli Ma, Tuan T. Nguyen, Eugene R. Schiff, Hie-Won L. Hann, Douglas T. Dieterich, Ronald G. Nahass, James S. Park, Sing Chan, Steven-Huy B. Han, Edward J. Gane, Michael Bennett, Katia Alves, Marc Evanchik, Ran Yan, Qi Huang, Uri Lopatin, Richard Colonno, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Ira M. Jacobson, Walid S. Ayoub, Frank Weilert, Natarajan Ravendhran, Alnoor Ramji, Paul Yien Kwo, Magdy Elkhashab, Tarek Hassanein, Ho S. Bae, Jacob P. Lalezari, Scott K. Fung, Mark S. Sulkowski
Publikováno v:
Journal of Hepatology. 77:642-652
HBV nucleos(t)ide reverse transcriptase inhibitors (NrtIs) do not completely suppress HBV replication. Previous reports indicate persistent viremia during NrtI treatment despite HBV DNA being undetectable. HBV core inhibitors may enhance viral suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7a77f9cac5a69525b2790e5ecdf2d1
https://doi.org/10.1016/j.jhep.2022.04.005
https://doi.org/10.1016/j.jhep.2022.04.005
Autor:
James Yao, Emily Bergsland, Rahul Aggarwal, Ana Aparicio, Himisha Beltran, Judy S Crabtree, Christine L Hann, Toni Ibrahim, Lauren A Byers, Hironobu Sasano, John Umejiego, Marianne Pavel
Publikováno v:
The Oncologist. 27:940-951
Introduction Neuroendocrine neoplasms (NEN) are heterogeneous malignancies that can arise at almost any anatomical site and are classified as biologically distinct well-differentiated neuroendocrine tumors (NET) and poorly differentiated neuroendocri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53db8978588d60bfb47c86fc4d2b1743
https://doi.org/10.1093/oncolo/oyac161
https://doi.org/10.1093/oncolo/oyac161