Zobrazeno 1 - 10
of 2 460
pro vyhledávání: '"L. Hann"'
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a rare central nervous system (CNS) pathology predominantly observed in the pediatric population. Ependymomas also exhibit a peak incidence in early childhood, with rare presentatio
Externí odkaz:
https://doaj.org/article/c3117e5986d74c64b20881a0ea2d353d
Autor:
Tia Cheunkarndee, BA, Matthew Z. Guo, BA, Stefanie Houseknecht, PharmD, Josephine L. Feliciano, MD, Christine L. Hann, MD, PhD, Vincent K. Lam, MD, Benjamin P. Levy, MD, Joseph C. Murray, MD, PhD, Julie R. Brahmer, MD, Patrick M. Forde, MBBCh, Kristen A. Marrone, MD, Susan C. Scott, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 6, Pp 100686- (2024)
Introduction: Up to 20% of EGFR-mutated NSCLC cases harbor uncommon EGFR mutations, including atypical exon 19 and compound mutations. Relatively little is known about the efficacy of osimertinib in these cases. Methods: Patients treated with first-l
Externí odkaz:
https://doaj.org/article/05807ac9bd2f42b798126635e1f75ec4
Autor:
Charles M. Rudin, Martin Reck, Melissa L. Johnson, Fiona Blackhall, Christine L. Hann, James Chih-Hsin Yang, Julie M. Bailis, Gwyn Bebb, Amanda Goldrick, John Umejiego, Luis Paz-Ares
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-21 (2023)
Abstract Small cell lung cancer (SCLC) is an aggressive neuroendocrine carcinoma with a poor prognosis. Initial responses to standard-of-care chemo-immunotherapy are, unfortunately, followed by rapid disease recurrence in most patients. Current treat
Externí odkaz:
https://doaj.org/article/10e1da2e3d234f1e801863a73f93ec88
Autor:
Laura C Cappelli, Patrick M Forde, Ami A Shah, Julie Brahmer, Joseph C Murray, Paola Ghanem, Vincent K Lam, Benjamin P Levy, Kristen A Marrone, Susan C Scott, Josephine L Feliciano, Christine L Hann, David S Ettinger, Christopher Mecoli
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Purpose Concomitant autoimmune rheumatic diseases (ARD) can add morbidity and complicate treatment decisions for patients with lung cancer. We evaluated the tumour characteristics at diagnosis and clinical outcomes in lung cancer patients with or wit
Externí odkaz:
https://doaj.org/article/0a0d1f66575040e49d7c3c68700e07dc
Autor:
Kai-li Liang, Sean Tackett, Samantha Myers, Julie R. Brahmer, Ilene S. Browner, David S. Ettinger, Patrick M. Forde, Russell K. Hales, Christine L. Hann, Vincent K. Lam, Kristen A. Marrone, Tricia Patel, Valerie Peterson, Sarah Sagorsky, Michelle Turner, Khinh R. Voong, Jarushka Naidoo, Josephine L. Feliciano
Publikováno v:
Current Oncology, Vol 29, Iss 6, Pp 4342-4353 (2022)
Introduction: With the increasing use of immune checkpoint inhibitors (ICI) for cancer, there is a growing burden on the healthcare system to provide care for the toxicities associated with these agents. Herein, we aim to identify and describe the di
Externí odkaz:
https://doaj.org/article/e7755653efc74e219febc8c1c7997306
Autor:
Aaron S. Mansfield, David S. Hong, Christine L. Hann, Anna F. Farago, Himisha Beltran, Saiama N. Waqar, Andrew E. Hendifar, Lowell B. Anthony, Matthew H. Taylor, Alan H. Bryce, Scott T. Tagawa, Karl Lewis, Jiaxin Niu, Christine H. Chung, James M. Cleary, Michael Rossi, Carrianne Ludwig, Ricardo Valenzuela, Yan Luo, Rahul Aggarwal
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-7 (2021)
Abstract Delta-like protein 3 (DLL3) is highly expressed in solid tumors, including neuroendocrine carcinomas/neuroendocrine tumors (NEC/NET). Rovalpituzumab tesirine (Rova-T) is a DLL3-targeting antibody-drug conjugate. Patients with NECs and other
Externí odkaz:
https://doaj.org/article/41cea5032a0d44ac9ceef9a9bed44b7a
Autor:
Susan C. Scott, Xiaoshan M. Shao, Noushin Niknafs, Archana Balan, Gavin Pereira, Kristen A. Marrone, Vincent K. Lam, Joseph C. Murray, Josephine L. Feliciano, Benjamin P. Levy, David S. Ettinger, Christine L. Hann, Julie R. Brahmer, Patrick M. Forde, Rachel Karchin, Jarushka Naidoo, Valsamo Anagnostou
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe magnitude of response to immune checkpoint inhibitor (ICI) therapy may be sex-dependent, as females have lower response rates and decreased survival after ICI monotherapy. The mechanisms underlying this sex dimorphism in ICI response
Externí odkaz:
https://doaj.org/article/2f91c0b2890647729b3fe999f6a97a89
Autor:
Joshua E. Reuss, MD, Emily Brigham, MD, MHS, Kevin J. Psoter, PhD, Khinh Ranh Voong, MD, Bairavi Shankar, BS, David S. Ettinger, MD, Kristen A. Marrone, MD, Christine L. Hann, MD, Benjamin Levy, MD, Josephine L. Feliciano, MD, Julie R. Brahmer, MD, David Feller-Kopman, MD, Andrew D. Lerner, MD, Hans Lee, MD, Lonny Yarmus, DO, Russell K. Hales, MD, Franco D’Alessio, MD, Sonye K. Danoff, MD, PhD, Patrick M. Forde, MBBCH, Karthik Suresh, MD, Jarushka Naidoo, MBBCH, MHS
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 10, Pp 100220- (2021)
Introduction: Checkpoint inhibitor pneumonitis (CIP) is a serious toxicity of anti–programmed death-(ligand) 1 immunotherapy. Whether pretreatment differences in pulmonary function exist in patients who develop CIP is unknown. We analyzed the pulmo
Externí odkaz:
https://doaj.org/article/d916673ba4b249d5ba179b35fe488531
Autor:
Lavanya Sivapalan, Wade T. Iams, Zineb Belcaid, Susan C. Scott, Noushin Niknafs, Archana Balan, James R. White, Prasad Kopparapu, Christopher Cann, Blair V. Landon, Gavin Pereira, Victor E. Velculescu, Christine L. Hann, Christine M. Lovly, Valsamo Anagnostou
Publikováno v:
Clinical Cancer Research. :OF1-OF14
Purpose: Patients with small-cell lung cancer (SCLC) have an exceptionally poor prognosis, calling for improved real-time noninvasive biomarkers of therapeutic response. Experimental Design: We performed targeted error-correction sequencing on 171 se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513e58885b12014079a0fd6aed4019ec
https://doi.org/10.1158/1078-0432.ccr-22-2242
https://doi.org/10.1158/1078-0432.ccr-22-2242
Autor:
Xing Wang, Natasha Raman, Ghali Lemtiri-Chlieh, Jinhee Chang, Shreya Jagtap, Dipanwita Dutta Chowdhury, Matthew Ballew, Francesca Anna Carrieri, Triet Nguyen, Katriana Nugent, Travis Peck, Michelle S. Levine, Aaron Chan, Christine Lam, Reem Malek, Tung Hoang, Ryan Phillips, ZhuoAn Cheng, Kekoa Taparra, Nick Connis, Christine L. Hann, Andrew Holland, Phuoc T. Tran, Audrey Lafargue, Hailun Wang
Publikováno v:
Molecular Cancer Therapeutics. 22:519-528
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c109ad13608c562d8b330269ae2aa510
https://doi.org/10.1158/1535-7163.mct-22-0191
https://doi.org/10.1158/1535-7163.mct-22-0191