Zobrazeno 1 - 10
of 100
pro vyhledávání: '"L. Grodzinska"'
Publikováno v:
European Journal of Clinical Pharmacology. 43:629-633
The nitrovasodilator and nitric oxide donor molsidomine and its metabolite SIN-I dilate vascular smooth muscle and inhibit platelet activation by increasing intracellular concentrations of cyclic GMP We have therefore studied the effects of molsidomi
Publikováno v:
Acta physiologica Hungarica. 84(4)
The stable prostacyclin analogue-iloprost and prostaglandin E1 (Alprostadil) showed a beneficial effect on activated platelets and leukocytes, and thrombocyte and leukocyte vessel interaction and damaged endothelium, improving microvascular perfusion
Publikováno v:
Acta physiologica Hungarica. 84(4)
Intravenous infusions of L-arginine (L-ARG) and placebo (saline) resulted in improvement of clinical assessments, statistically significant after L-ARG but not after saline. Results of laboratory estimations for platelet and fibrynolysis changed sign
Publikováno v:
European journal of clinical pharmacology. 43(6)
The nitrovasodilator and nitric oxide donor molsidomine and its metabolite SIN-I dilate vascular smooth muscle and inhibit platelet activation by increasing intracellular concentrations of cyclic GMP. We have therefore studied the effects of molsidom
Publikováno v:
Zeitschrift fur Kardiologie. 80
The influence of molsidomine on endogenous fibrinolytic activity was studied in a double-blind, randomized, placebo-controlled trial involving 12 male healthy volunteers. When measured 3 h after oral intake of molsidomine (16 mg, slow-release formula
Publikováno v:
Experientia. 20:435-437
An nicht narkotisierten Katzen wurde die Wirkung einer direkten lokalen chemischen Reizung subkortikaler Strukturen durch Melatonin untersucht. Diese Substanz, appliziert im Bereich der Area praeoptica, loste trophotropische Effekte und Schlaf aus.
Publikováno v:
Therapia Hungarica (English edition). 33(2)
Publikováno v:
The Journal of pharmacy and pharmacology. 27(2)
Challenges of the superfused (1 ml min−1) trachea with histamine (100–200 μg) result in the release of prostaglandin E-like material (3–25 ng in terms of prostaglandin E2) but no prostaglandin F-like activity has been detected in the superfusa
Publikováno v:
Pathologie-biologie. 35(2 Pt 2)
Molsidomine and its active metabolite SIN-1 were examined in humans and animals for their fibrinolytic and antithrombotic activity. In humans six and eight hours after ingestion of molsidomine retard (8 mg) a marked shortening of euglobulin clot lysi