Exercise capacity and cardiac allograft ischemic time in recent heart transplant recipients

Autor: Katelyn D. Bosteder, MS, CCRP, ACSM-CEP, EIM, Johanna S. van Zyl, PhD, Arturo A. Arce-Esquivel, MD, PhD, Cheryl Cooper, MSN, PhD, Joost Felius, PhD, Robert L. Gottlieb, MD, PhD

Publikováno v: JHLT Open, Vol 5, Iss , Pp 100115- (2024)

Background: Prolonged ischemic times (IT) for transplant hearts transported under cold storage conditions are associated with an increased risk of mortality; however, the impact of IT on functional outcomes, such as exercise capacity (EC), is not ful

Externí odkaz: https://doaj.org/article/1c3cd7b7563e4631ab4b5fc48ebd631c

Treatment of patients hospitalized for COVID-19 with remdesivir is associated with lower likelihood of 30-day readmission: a retrospective observational study

Autor: Essy Mozaffari, Aastha Chandak, Robert L Gottlieb, Chidinma Chima-Melton, Andre C Kalil, Vishnudas Sarda, Celine Der-Torossian, Thomas Oppelt, Mark Berry, Alpesh N Amin

Publikováno v: Journal of Comparative Effectiveness Research, Vol 13, Iss 4 (2024)

Aim: This observational study investigated the association between remdesivir treatment during hospitalization for COVID-19 and 30-day COVID-19-related and all-cause readmission across different variants time periods. Patients & methods: Hospitaliz

Externí odkaz: https://doaj.org/article/f5ef90f9d18d41ecbf9b247427c75042

Consistent Effects of Early Remdesivir on Symptoms and Disease Progression Across At-Risk Outpatient Subgroups: Treatment Effect Heterogeneity in PINETREE Study

Autor: Samuel M. Brown, Morgan J. Katz, Adit A. Ginde, Kavita Juneja, Monica Ramchandani, Joshua T. Schiffer, Carlos Vaca, Robert L. Gottlieb, Yuan Tian, Emon Elboudwarej, Joshua A. Hill, Richard Gilson, Lauren Rodriguez, Charlotte Hedskog, Shuguang Chen, Jairo M. Montezuma-Rusca, Anu Osinusi, Roger Paredes

Publikováno v: Infectious Diseases and Therapy, Vol 12, Iss 4, Pp 1189-1203 (2023)

Abstract Introduction In the PINETREE study, early remdesivir treatment reduced risk of coronavirus disease 2019 (COVID-19)-related hospitalizations or all-cause death versus placebo by 87% by day 28 in high-risk, non-hospitalized patients. Here we r

Externí odkaz: https://doaj.org/article/92c2e56adfd9476080f60f8837813ee7

Monoclonal Antibodies in Hospitalised Patients with COVID-19: The Role of SARS-COV-2 Serostatus in an Evolving Pandemic

Autor: François Raffi, Robert L. Gottlieb

Publikováno v: Infectious Diseases and Therapy, Vol 12, Iss 3, Pp 735-747 (2023)

Abstract Appropriately selected neutralising monoclonal antibodies (nmAbs) are an effective treatment for patients with mild or moderate coronavirus disease 2019 (COVID-19) who are at high risk of progression to severe disease. In contrast, the effic

Externí odkaz: https://doaj.org/article/66d04e4ee93440c5986967b5b2d39894

Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis

Autor: Chris Gale, Marian Knight, Kirsty Le Doare, Erica M Lokken, Laura A Magee, Peter von Dadelszen, Nathalie Broutet, Emily R Smith, Deborah Money, Stephanie Jones, Olof Stephansson, Lesley Regan, Fouzia Farooq, Christoph Lees, Julia Townson, Sami L Gottlieb, Jonas Söderling, Jorge Carrillo, Anna Thorson, Marleen Temmerman, Joyce Were, Edward Mullins, Ajay Reddy, Valerie J Flaherman, Clayton Onyango, Shabir A Madhi, Antonio Lanzone, Liona C Poon, Alice Panchaud, Musa Sekikubo, Eduard Gratacos, Renate Strehlau, Cande V. Ananth, Jorge E Tolosa, Justin S Brandt, Jennifer Hill, Erich Cosmi, Lauren Hookham, Raigam Jafet Martínez-Portilla, Francesca Crovetto, Fatima Crispi, Robert Mboizi, Jean B Nachega, Silvia Visentin, Erin Oakley, Gargi Wable Grandner, Kacey Ferguson, Yalda Afshar, Mia Ahlberg, Homa Ahmadzia, Victor Akelo, Grace Aldrovandi, Beth A Tippett Barr, Elisa Bevilacqua, Irene Fernández Buhigas, Rebecca Clifton, Jeanne Conry, Camille Delgado-López, Hema Divakar, Amanda J Driscoll, Guillaume Favre, Maria M Gil, Olivia Hernandez, Erkan Kalafat, Sammy Khagayi, Karen Kotloff, Ethan Litman, Valentina Laurita Longo, Elizabeth M McClure, Tori D Metz, Emily S Miller, Sakita Moungmaithong, Marta C Nunes, Dickens Onyango, Daniel Raiten, Gordon Rukundo, Daljit Sahota, Allie Sakowicz, Jose Sanin-Blair, Miguel Valencia-Prado, Kristina Adams Waldorf, Clare Whitehead, Murat Yassa, Jim M Tielsch, Eduard Langenegger, Nadia A. Sam-Agudu, Onesmus W. Gachuno, Denis M. Mukwege, Richard Omore, Gregory Ouma, Kephas Otieno, Zacchaeus Abaja Were, Pinar Birol İlter, Federica Meli, Giulia Bonanni, Federica Romanzi, Eleonora Torcia, Chiara di Ilio, Haylea Sweat Patrick, Vuyelwa Baba, Mary Adam, Philiswa Mlandu, Yasmin Adam

Publikováno v: BMJ Global Health, Vol 8, Iss 1 (2023)

Introduction Despite a growing body of research on the risks of SARS-CoV-2 infection during pregnancy, there is continued controversy given heterogeneity in the quality and design of published studies.Methods We screened ongoing studies in our sequen

Externí odkaz: https://doaj.org/article/212bea15d2284af082c33d055b991512