Zobrazeno 1 - 10
of 25
pro vyhledávání: '"L. Godmann"'
Autor:
Giulia De Rossi, Thomas Pap, Adelheid Korb-Pap, James R. Whiteford, U König, Denise Beckmann, L. Godmann, Katja Mühlenberg, Jessica Bertrand, Frank Echtermeyer, M. Bollmann, J. Sherwood
Publikováno v:
Annals of the rheumatic diseases. 79(4)
ObjectiveSyndecan-4 (sdc4) is a cell-anchored proteoglycan that consists of a transmembrane core protein and glucosaminoglycan (GAG) side chains. Binding of soluble factors to the GAG chains of sdc4 may result in the dimerisation of sdc4 and the init
Autor:
L. Godmann, Thomas Pap, Claire Jacques, Xavier Houard, Francis Berenbaum, Colette Salvat, Carole Bougault, Marjolaine Gosset
Publikováno v:
Arthritis & Rheumatism. 64:3972-3981
Objective The main feature of osteoarthritis (OA) is degradation and loss of articular cartilage. Interleukin-1β (IL-1β) is thought to have a prominent role in shifting the metabolic balance toward degradation. IL-1β is first synthesized as an ina
Publikováno v:
Aktuelle Rheumatologie. 37:358-365
Die Osteoarthrose (OA) ist im Gegensatz zur rheumatoiden Arthritis eine primar degenerative Gelenkerkrankung. Neue Erkenntnisse zeigen allerdings, dass die OA keine rein passive Verschleiserkrankung ist, sondern ein aktiver Prozess, der auf einem kom
Autor:
Thomas Pap, Carole Bougault, Marjolaine Gosset, Xavier Houard, Francis Berenbaum, L. Godmann, Claire Jacques, Colette Salvat
Publikováno v:
Bone Abstracts.
Autor:
Thomas Pap, Peter Paruzel, Katja Neugebauer, Adelheide Korb, Athanasios Stratis, Jessica Bertrand, George Kollias, L. Godmann, Corinna Wemeyer, C Cromme, Berno Dankbar, Mareike Fröhling, Frank Echtermeyer
Publikováno v:
Arthritis Research & Therapy
Autor:
Thomas Pap, Jessica Bertrand, Francesco Dell'Accio, Peter Bruckner, Melanie Timmen, L. Godmann, Richard Stange, G. Nalesso, Frank Echtermeyer, Heriburg Hidding, Rita Dreier, Michael J. Raschke
Publikováno v:
Arthritis and rheumatism. 65(3)
Objective Syndecan 4, a heparan sulfate proteoglycan, has been associated with osteoarthritis. The present study was undertaken to analyze the functional role of syndecan 4 in endochondral ossification of mouse embryos and in adult fracture repair, w
Autor:
L. Godmann, T. Kräft, Thelonius Hawellek, Jessica Bertrand, Frédéric Lioté, Thomas Pap, Jan Hubert, Yvonne Nitschke
Publikováno v:
Osteoarthritis and Cartilage. 22:S170-S171
T. Kraft1, L. Godmann1, T. Hawellek2, J. Hubert2, Y. Nitschke3, F. Liote4, T. Pap1, J. Bertrand1 1 Institute for Experimental Musculoskeletal Medicine, University Hospital Munster, Germany 2 Centre for Orthopaedics and Trauma Surgery Bad Bramstedt, U
Autor:
Uwe Hansen, Frank Echtermeyer, L. Godmann, C.K. Clarke, Thomas Pap, Jessica Bertrand, F Dell’Accio, A. Held, J. Sherwood, G. Nalesso, Richard Stange
Publikováno v:
Annals of the Rheumatic Diseases. 74:A40.2-A41
Background The heparan sulfate proteoglycan syndecan-4 (Sdc4) is a regulator of various cartilage-related processes including osteoarthritis (OA). Blockade of Sdc4 signalling protects mice from cartilage degradation in experimentally induced OA. OA i
Autor:
Frank Echtermeyer, Francesco Dell'Accio, Heriburg Hidding, Thomas Pap, Jessica Bertrand, Richard Stange, Rita Dreier, G. Nalesso, L. Godmann
Publikováno v:
Osteoarthritis and Cartilage. 20:S25-S26
Autor:
Frank Echtermeyer, Jessica Bertrand, Rita Dreier, Francesco Dell'Accio, G. Nalesso, L. Godmann, Richard Stange, Heriburg Hidding, Thomas Pap
Publikováno v:
Annals of the Rheumatic Diseases. 71:644.16-644
Background Syndecan-4 (Sdc4) is a heparan sulfate proteoglycan that has been strongly associated with osteoarthritis, a disease that mimics key aspects of early cartilage remodelling during endochondral ossification. The role of Sdc4 in embryonic and