Zobrazeno 1 - 10
of 19
pro vyhledávání: '"L. Giandomenico"'
Autor:
F. Tauro, A. Petroselli, M. Porfiri, L. Giandomenico, G. Bernardi, F. Mele, D. Spina, S. Grimaldi
Publikováno v:
Geoscientific Instrumentation, Methods and Data Systems, Vol 5, Iss 1, Pp 241-251 (2016)
Flow monitoring of riverine environments is crucial for hydrology and hydraulic engineering practice. Besides few experimental implementations, flow gauging relies on local water level and surface-flow velocity measurements through ultrasonic meters
Externí odkaz:
https://doaj.org/article/14613a81410f4bd5bf10c0ce256fcde8
Publikováno v:
FEBS Open Bio, Vol 13, Iss 7, Pp 1164-1176 (2023)
Gaining a mechanistic understanding of the molecular pathways underpinning cellular and organismal physiology invariably relies on the perturbation of an experimental system to infer causality. This can be achieved either by genetic manipulation or b
Externí odkaz:
https://doaj.org/article/edee7048f439482d907aa88e5e58f645
Autor:
Patrick C Hoffmann, Stefano L Giandomenico, Iva Ganeva, Michael R Wozny, Magdalena Sutcliffe, Madeline A Lancaster, Wanda Kukulski
Publikováno v:
eLife, Vol 10 (2021)
During brain development, axons must extend over great distances in a relatively short amount of time. How the subcellular architecture of the growing axon sustains the requirements for such rapid build-up of cellular constituents has remained elusiv
Externí odkaz:
https://doaj.org/article/02bc299a719544eaa41e48038e4ecda2
Autor:
Chao Sun, Kristina Desch, Belquis Nassim-Assir, Stefano L. Giandomenico, Paulina Nemcova, Julian D. Langer, Erin M. Schuman
Publikováno v:
Science
The proteasome, the major protein-degradation machine in cells, regulates neuronal synapses and long-term information storage. Here, using super-resolution microscopy, we found that the two essential subcomplexes of the proteasome, the regulatory (19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abf244a5892419430ed5e4983639990
https://hdl.handle.net/21.11116/0000-000D-3688-D
https://hdl.handle.net/21.11116/0000-000D-3688-D
Publikováno v:
Trends in Neurosciences
Neurons continuously adapt to external cues and challenges, including stimulation, plasticity-inducing signals and aging. These adaptations are critical for neuronal physiology and extended survival. Proteostasis is the process by which cells adjust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ca238c5f769bb7891bb8be55d43506
https://doi.org/10.1016/j.tins.2021.08.002
https://doi.org/10.1016/j.tins.2021.08.002
Autor:
Chao Sun, Kristina Desch, Belquis Nassim-Assir, Stefano L. Giandomenico, Paulina Nemcova, Julian D. Langer, Erin M. Schuman
The major protein-degradation machine, the proteasome, functions at brain synapses and regulates long-term information storage. Here we found that the two essential subcomplexes of the proteasome, the regulatory (19S) and catalytic (20S) particles th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c23085a2ee67139834ea8e9b035a02
https://doi.org/10.1101/2022.10.17.512557
https://doi.org/10.1101/2022.10.17.512557
Publikováno v:
Neuromethods ISBN: 9781071627198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c250acfe1f7c248cb3a1accf70c89bf
https://doi.org/10.1007/978-1-0716-2720-4_1
https://doi.org/10.1007/978-1-0716-2720-4_1
Autor:
Michael R. Wozny, Patrick C. Hoffmann, Wanda Kukulski, Iva Ganeva, Madeline A. Lancaster, Stefano L. Giandomenico, Magdalena Sutcliffe
Publikováno v:
Hoffmann, Patrick C; Giandomenico, Stefano L; Ganeva, Iva; Wozny, Michael R; Sutcliffe, Magdalena; Lancaster, Madeline A; Kukulski, Wanda (2021). Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids. eLife, 10 eLife Sciences Publications 10.7554/eLife.70269
eLife, Vol 10 (2021)
eLife
eLife, Vol 10 (2021)
eLife
Funder: Natural Sciences and Engineering Research Council of Canada; FundRef: http://dx.doi.org/10.13039/501100000038
During brain development, axons must extend over great distances in a relatively short amount of time. How the subcellular arch
During brain development, axons must extend over great distances in a relatively short amount of time. How the subcellular arch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2e0c1cc9e3d11cd3c74ed7b6e06ff4
https://doi.org/10.7554/elife.70269
https://doi.org/10.7554/elife.70269
Autor:
Michael R. Wozny, Patrick C. Hoffmann, Madeline A. Lancaster, Wanda Kukulski, Stefano L. Giandomenico, Magdalena Sutcliffe, Iva Ganeva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::669f0f745deb6d8e7b369ff9de3384af
https://doi.org/10.7554/elife.70269.sa2
https://doi.org/10.7554/elife.70269.sa2
Publikováno v:
Nature Protocols
Nat Protoc
Nat Protoc
Cerebral organoids, or brain organoids, can be generated from a wide array of emerging technologies for modeling brain development and disease. The fact that they are cultured in vitro makes them easily accessible both genetically and for live assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f670c117eda6faf3d9344ffc3e26b95b