Zobrazeno 1 - 10
of 134
pro vyhledávání: '"L. Gaffo"'
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Objective To determine if methotrexate or folic acid prescription was associated with differential risk for COVID-19 diagnosis or mortality.Design Case–control analysis.Setting The population-based UK Biobank (UKBB) cohort.Participants Data from 38
Externí odkaz:
https://doaj.org/article/a8ff62656ebe47a3a970fbc563fe0ef0
Autor:
Huai Leng Pisaniello, Mark C. Fisher, Hamish Farquhar, Ana Beatriz Vargas-Santos, Catherine L. Hill, Lisa K. Stamp, Angelo L. Gaffo
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-18 (2021)
Abstract Gout flare prophylaxis and therapy use in people with underlying chronic kidney disease (CKD) is challenging, given limited treatment options and risk of worsening renal function with inappropriate treatment dosing. This literature review ai
Externí odkaz:
https://doaj.org/article/a9b2cd32111d4965b307ccb47208a308
Autor:
Mariana Urquiaga, Angelo L. Gaffo
Publikováno v:
Gout, Urate, and Crystal Deposition Disease. 1:37-48
Gout is a prevalent and burdensome condition despite the advances in our knowledge of its underlying mechanisms, prevention, and treatment. There is still work to be done to elucidate relevant questions that could lead to better patient care. This co
Autor:
Mengying Sun, Ana I. Vazquez, Richard J. Reynolds, Jasvinder A. Singh, Mathew Reeves, Tony R. Merriman, Angelo L. Gaffo, Gustavo de los Campos
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Many gout comorbidities (e.g., hypertension) are correlated with serum urate. In this investigation, we identified risk factors (e.g., systolic blood pressure [SBP]), that (1) are associated with incident gout, (2) have effects on
Externí odkaz:
https://doaj.org/article/7458e45350db42b4ae846fa635980991
Autor:
Joshua Melnick, Amy S. Mudano, Angelo L. Gaffo, Nicola Dalbeth, Jeffrey Foster, Anthony Doyle, Stephanie R. Biggers-Clark, Anne Horne, David T. Redden, Kenneth G. Saag
Publikováno v:
Seminars in Arthritis and Rheumatism. 51:1218-1223
Background/Purpose Disordered osteoclast activity has been implicated in the pathogenesis of gouty bone erosion. We sought to determine if the addition of denosumab (a monoclonal antibody targeting the receptor activator of nuclear factor kappa-B lig
Autor:
Nagisa Morikawa, Yuichiro Yano, Angelo L. Gaffo, Myron D. Gross, David R. Jacobs, Daniel Duprez, Masanari Kuwabara, Michael P. Bancks
Publikováno v:
Hypertension
Serum urate levels have been shown to be correlated with risk for incident cardiovascular disease (CVD) events among middle-aged or older adults. However, serum urate trajectory during young adulthood and its association with CVD events has been unde
Publikováno v:
BMC Rheumatology, Vol 5, Iss 1, Pp 1-7 (2021)
BMC Rheumatology
BMC Rheumatology
Background Previous studies have noted significant variation in serum urate (sUA) levels, and it is unknown how this influences the accuracy of hyperuricemia classification based on single data points. Despite this known variability, hyperuricemic pa
Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities
Autor:
Robert Terkeltaub, Lisa K. Stamp, David B. Mount, Huai Leng Pisaniello, Angelo L. Gaffo, Mark Fisher, Hyon K. Choi, Ana Beatriz Vargas-Santos, Hamish Farquhar, Christopher Hill
Publikováno v:
Nature Reviews. Rheumatology
Gout and chronic kidney disease (CKD) frequently coexist, but quality evidence to guide gout management in people with CKD is lacking. Use of urate-lowering therapy (ULT) in the context of advanced CKD varies greatly, and professional bodies have iss
Autor:
Kenneth G. Saag, Leslie Lang, Elsayed Z. Soliman, S. Louis Bridges, Tony R. Merriman, Ninad S. Chaudhary, George Howard, Lisandro D. Colantonio, Monika M. Safford, Richard J. Reynolds, Timothy B Plante, Nicole D. Armstrong, Paul Muntner, Angelo L. Gaffo, Marguerite R. Irvin, Jeffrey R. Curtis, Jasvinder A. Singh
Publikováno v:
J Rheumatol
Objective.To determine the association of serum urate (SU) levels with sudden cardiac death and incident coronary heart disease (CHD), separately, among adults without a history of CHD.Methods.We conducted a case-cohort analysis of Black and White pa
Publikováno v:
BMJ open, vol 12, iss 8
ObjectiveTo determine if methotrexate or folic acid prescription was associated with differential risk for COVID-19 diagnosis or mortality.DesignCase–control analysis.SettingThe population-based UK Biobank (UKBB) cohort.ParticipantsData from 380 38