Zobrazeno 1 - 10 of 25 pro vyhledávání: '"L. Gabison"'
1
X-ray, ESR, and quantum mechanics studies unravel a spin well in the cofactor-less urate oxidase
Autor: Bertrand Castro, Mohamed El Hajji, Nathalie Colloc'h, Thierry Prangé, Fabienne Peyrot, M. Chiadmi, L. Gabison, Muhannad Altarsha, Claude Chopard, Gérald Monard
Publikováno v: Proteins: Structure, Function, and Bioinformatics. 79:1964-1976
Urate oxidase (EC 1.7.3.3 or UOX) catalyzes the conversion of uric acid using gaseous molecular oxygen to 5-hydroxyisourate and hydrogen peroxide in absence of any cofactor or transition metal. The catalytic mechanism was investigated using X-ray dif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc7a8241e65071d08b087c325780dda6
https://doi.org/10.1002/prot.23022
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2
Synthetic Route to Dinuclear Platinum(II) Complexes [{trans-PtCl(NH3)2}2(μ-L)]2+ (L = Aliphatic or Heterocyclic Diamine) as Potential Antitumor Agents, Exploiting the Mutual Activation of Hydroxido Ligands and Ammonium Groups
Autor: Christiane Garbay, Jirri Kozelka, Michel Vidal, Alberto Albinati, Silvia Rizzato, Christine Lenoir, L. Gabison, Jorma Arpalahti, Claude Chopard
Publikováno v: Inorganic Chemistry. 47:9701-9705
A simple and efficient method for the synthesis of potentially antitumor-active dinuclear platinum complexes of the general formula [{trans-PtCl(NH3)2}2(μ-L)](n+2)+ (L = aliphatic or heterocyclic diamine; n = charge of L) is presented. The procedure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50b6186e06381fd5259bdbd65e4a6f96
https://doi.org/10.1021/ic801251k
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3
Azide inhibition of urate oxidase
Autor: Nathalie Colloc'h, Thierry Prangé, L. Gabison
Publikováno v: Acta crystallographica. Section F, Structural biology communications
Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd, 2014, 70 (7), pp.896-902. 〈10.1107/S2053230X14011753〉
Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd, 2014, 70 (7), pp.896-902. ⟨10.1107/S2053230X14011753⟩
Acta crystallographica Section F : Structural biology communications [2014-...]
Acta crystallographica Section F : Structural biology communications [2014-..], 2014, 70 (7), pp.896-902. ⟨10.1107/S2053230X14011753⟩
The inhibition of urate oxidase (UOX) by azide was investigated by X-ray diffraction techniques and compared with cyanide inhibition. Two well characterized sites for reagents are present in the enzyme: the dioxygen site and the substrate-binding sit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe41ea4a0c0b7b3faa8661d94137e9c8
https://hal.archives-ouvertes.fr/hal-01626305
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4
A Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study
Autor: Jana Sopkova-de Oliveira Santos, Jacques H. Abraini, G. Marassio, Nathalie Colloc'h, Hélène N. David, Thierry Prangé, Nicolas Delcroix, L. Gabison
Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2011, 25, pp.1-10. ⟨10.1096/fj.11-183046⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2011, 25, pp.1-10. 〈10.1096/fj.11-183046〉
FASEB Journal, 2011, 25, pp.1-10. ⟨10.1096/fj.11-183046⟩
The remarkably safe anesthetics xenon (Xe) and, to lesser extent, nitrous oxide (N(2)O) possess neuroprotective properties in preclinical studies. To investigate the mechanisms of pharmacological action of these gases, which are still poorly known, w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d6a9f05c5e27f1b15c8fa886ed32e3
https://hal.archives-ouvertes.fr/hal-01061836
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5
Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand
Autor: L. Gabison, Thierry Prangé, M. Chiadmi, Bertrand Castro, Nathalie Colloc'h, Mohamed El Hajji
Publikováno v: Acta crystallographica. Section D, Biological crystallography. 66(Pt 6)
Urate oxidase (uricase; EC 1.7.3.3; UOX) fromAspergillus flavuscatalyzes the oxidation of uric acid in the presence of molecular oxygen to 5-hydroxyisourate in the degradation cascade of purines; intriguingly, catalysis proceeds using neither a metal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eddf86e0d3ae9c29b878ac0a340529a
https://pubmed.ncbi.nlm.nih.gov/20516624
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6
Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications
Autor: Nathalie Colloc'h, M. Chiadmi, Bertrand Castro, L. Gabison, Thierry Prangé, Mohamed El Hajji
Publikováno v: BMC Structural Biology, Vol 8, Iss 1, p 32 (2008)
BMC Structural Biology
Background Urate oxidase (EC 1.7.3.3 or UOX) catalyzes the conversion of uric acid and gaseous molecular oxygen to 5-hydroxyisourate and hydrogen peroxide, in the absence of cofactor or particular metal cation. The functional enzyme is a homo-tetrame
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21da4d72e5d0b5b35d9a19e8f04314b7
http://www.biomedcentral.com/1472-6807/8/32
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7
Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism
Autor: M. Chiadmi, Bertrand Castro, Mohamed El Hajji, Jana Sopkova-de Oliveira Santos, Jacques H. Abraini, G. Marassio, Nathalie Colloc'h, Gérald Monard, Muhannad Altarsha, Thierry Prangé, L. Gabison
Publikováno v: Biophysical journal. 95(5)
The localization of dioxygen sites in oxygen-binding proteins is a nontrivial experimental task and is often suggested through indirect methods such as using xenon or halide anions as oxygen probes. In this study, a straightforward method based on x-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022c2ae3a03b0e5db5e143973200564a
https://pubmed.ncbi.nlm.nih.gov/18375516
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8
Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase
Autor: Nathalie Colloc'h, Bertrand Castro, M. Chiadmi, Mohamed El Hajji, L. Gabison, Thierry Prangé
Publikováno v: FEBS Letters
FEBS Letters, Wiley, 2006, 580, pp.2087-2091
Urate oxidase from Aspergillus flavus catalyzes the degradation of uric acid to [S]-allantoin through 5-hydroxyisourate as a metastable intermediate. The second degradation step is thought either catalyzed by another specific enzyme, or spontaneous.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3678651bfd0e73b4e720a9e361833905
https://hal.archives-ouvertes.fr/hal-00022681
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10
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