Research on heterocyclic compounds. XXXI. Synthesis and antiinflammatory activity of 2-arylimidazo[1,2-a]pyrazine-3-carboxylic acids

Autor: Francesca Rossi, L Gomez Paloma, Maria Grazia Rimoli, Michele D'Amico, P. De Caprariis, V. Calderaro, Enrico Abignente, C Parrillo, L. Avallone

Publikováno v: European Journal of Medicinal Chemistry. 28:337-346

The synthesis of a series of 2-phenyl- and 2-(p-chlorophenyl)imidazo[1,2-a]pyrazine-3-carboxylic esters and acids is described. The structures of the new compounds were supported by 1H- and 13C-NMR spectra. These compounds were evaluated in vivo for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12093c519cd4091dfe64a1c97166f916
https://doi.org/10.1016/0223-5234(93)90150-d

Calcoli quantomeccanici di parametri NMR nella caratterizzazione strutturale di sostanze organiche: determinazione della configurazione relativa della Callipeltina A

Autor: C. Bassarello, L. Gomez Paloma, M. C. Monti, R. Riccio, G. Bifulco, ZAMPELLA, ANGELA, D'AURIA, MARIA VALERIA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::69400dd3674c3b1462816f9b7b73e8b5
http://hdl.handle.net/11588/505437

NUCLEOPHILIC CYCLOPROPANE RING OPENING IN DUOCARMYCIN SA DERIVATIVES BY METHANOL UNDER ACID CONDITIONS: A QUANTUM MECHANICAL STUDY IN GAS-PHASE AND IN SOLUTION

Autor: BARONE, Vincenzo, P. CIMINO, R. IMPROTA, G. BIFULCO, L. GOMEZ PALOMA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bf1660c8753469ab8f97f5a7f4f042ad
http://hdl.handle.net/11588/5939

Nucleophilic Cyclopropane Ring Opening in Duocarmycin SA Derivatives by Methanol under Acid Conditions: A Quantum Mechanical Study in the Gas-Phase and in Solution

Autor: P. Cimino, R. Improta, G. Bifulco, R. Riccio, L. Gomez-Paloma, V. Barone, V

Publikováno v: Journal of organic chemistry 69 (2004): 2816–2824.
info:cnr-pdr/source/autori:P. Cimino, R. Improta, G. Bifulco, R. Riccio, L. Gomez-Paloma, V. Barone, V/titolo:Nucleophilic Cyclopropane Ring Opening in Duocarmycin SA Derivatives by Methanol under Acid Conditions: A Quantum Mechanical Study in the Gas-Phase and in Solution/doi:/rivista:Journal of organic chemistry/anno:2004/pagina_da:2816/pagina_a:2824/intervallo_pagine:2816–2824/volume:69

We present a quantum-mechanical study of the SN2 acid-catalyzed solvolysis with methanol of seven simplified duocarmycin SA (DNA alkylating agent) derivatives characterized by spirocyclic systems of increasing complexity, all containing the cycloprop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::daca094a1448ad5b51bcfd86b5b37d05
http://www.cnr.it/prodotto/i/13436

Progressi verso la definizione della stereochimica e la sintesi totale degli sfinxolidi

Autor: ZAMPELLA, ANGELA, D'AURIA, MARIA VALERIA, SEPE, VALENTINA, R. D’Orsi, G. Bifulco, C. Bassarello, L. Gomez Paloma, R. Riccio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::482de8bb0bf2be50ba3476bc278125b2
http://hdl.handle.net/11588/413199