Zobrazeno 1 - 10
of 29
pro vyhledávání: '"L. G. Presta"'
Autor:
W A Werther, T N Gonzalez, S J O'Connor, S McCabe, B Chan, T Hotaling, M Champe, J A Fox, P M Jardieu, P W Berman, L G Presta
Publikováno v:
The Journal of Immunology. 157:4986-4995
Lymphocyte function-associated antigen 1 (LFA-1; CD11a/CD18) is involved in leukocyte adhesion during cellular interactions essential for immunologic responses and inflammation. mAbs against LFA-1 have been shown to inhibit several T cell-dependent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f7bda02d82532f82e764ed141f41632
https://doi.org/10.4049/jimmunol.157.11.4986
https://doi.org/10.4049/jimmunol.157.11.4986
Autor:
J L Viney, S Jones, H H Chiu, B Lagrimas, M E Renz, L G Presta, D Jackson, K J Hillan, S Lew, S Fong
Publikováno v:
The Journal of Immunology. 157:2488-2497
The leukocyte integrin receptor, alpha 4 beta 7, and the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) are postulated to be important in regulating lymphocyte trafficking to normal intestine. Here we provide the first description of MAdCAM-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4252c93b5e89185ec3627525637c75a5
https://doi.org/10.4049/jimmunol.157.6.2488
https://doi.org/10.4049/jimmunol.157.6.2488
Publikováno v:
The EMBO Journal. 15:4919-4927
Vascular endothelial growth factor (VEGF) is an angiogenic inducer that mediates its effects through two high affinity receptor tyrosine kinases, Flt-1 and KDR. Flt-1 is required for endothelial cell morphogenesis whereas KDR is involved primarily in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a006aa5736c121e01dbd0234aa248f5
https://doi.org/10.1002/j.1460-2075.1996.tb00872.x
https://doi.org/10.1002/j.1460-2075.1996.tb00872.x
Publikováno v:
The Journal of Immunology. 155:5257-5267
The integrin receptors alpha 4 beta 1 and alpha 4 beta 7 both bind to vascular cell adhesion molecule-1 (VCAM-1). Here, we report that the amino acid residue requirements for murine VCAM-1 adhesion to murine alpha 4 beta 1 (WEHI 231) and alpha 4 beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42687324ba51d05bd5a7f02df78d72aa
https://doi.org/10.4049/jimmunol.155.11.5257
https://doi.org/10.4049/jimmunol.155.11.5257
Autor:
Lori Y. O'Connell, Cornelia M. Gorman, L. G. Presta, S J Lahr, Robert L. Shields, P Jardieu, J P Porter
Publikováno v:
Journal of Biological Chemistry. 269:26368-26373
Immunoglobulin (Ig) E antibodies mediate allergic responses by binding to specific high affinity receptors, Fc epsilon RI, on mast cells and basophils. Previous studies have shown that the principal Fc epsilon RI binding site is located on the third
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b509aa97f6f5f8dc98114e7931b0d83d
https://doi.org/10.1016/s0021-9258(18)47203-1
https://doi.org/10.1016/s0021-9258(18)47203-1
Publikováno v:
The Journal of Cell Biology
This study describes the identification of seven amino acid residues of the vascular cell adhesion molecule (VCAM-1) that influence binding to the alpha 4 beta 1 receptor. Using recombinant murine VCAM-1-IgG, which is bound by both mouse (WEHI 231) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477a9dc501a22964c696bca6a275bd33
http://europepmc.org/articles/PMC2290915
http://europepmc.org/articles/PMC2290915
Publikováno v:
The Journal of Immunology. 151:2623-2632
IgE antibodies bind to specific high-affinity receptors on mast cells, leading to mast cell degranulation and release of mediators, such as histamine, which produce symptoms associated with allergy. Hence, anti-IgE antibodies that block binding of Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf9375aa876e4bcd000b7fe0f0bdbf1
https://doi.org/10.4049/jimmunol.151.5.2623
https://doi.org/10.4049/jimmunol.151.5.2623
Autor:
D V Erbe, L G Presta, R J Ramos, J M Rumberger, B N Rao, C Foxall, B K Brandley, B A Wolitzky, D K Burns, C R Norton
Publikováno v:
The Journal of Cell Biology. 119:215-227
E-selectin elicits cell adhesion by binding to the cell surface carbohydrate, sialyl Lewis X (sLe(x)). We evaluated the effects of mutations in the E-selectin lectin domain on the binding of a panel of anti-E-selectin mAbs and on the recognition of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e964d0ba0d27e37cb555174f398d32bf
https://doi.org/10.1083/jcb.119.1.215
https://doi.org/10.1083/jcb.119.1.215
Publikováno v:
The Journal of Experimental Medicine
The HER2 protooncogene encodes a 185-kD transmembrane phosphoglycoproteins, human epidermal growth factor receptor 2 (p185HER2), whose amplified expression on the cell surface can lead to malignant transformation. Overexpression of HER2/p185HER2 is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112299d1c91a10fd38f40c0065c3f121
http://europepmc.org/articles/PMC2119072
http://europepmc.org/articles/PMC2119072
Publikováno v:
Biochemical Society transactions. 30(4)
The binding sites on human IgG1 for human Fc gamma receptor (Fc gamma R) I, Fc gamma RIIa, Fc gamma RIIb, Fc gamma RIIIa and neonatal FcR have been mapped. A common set of IgG1 residues is involved in binding to all Fc gamma Rs, while Fc gamma RII an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e61f9cc63c74e37bfac30bf398b741
https://pubmed.ncbi.nlm.nih.gov/12196120
https://pubmed.ncbi.nlm.nih.gov/12196120