Zobrazeno 1 - 10
of 44
pro vyhledávání: '"L. G. Lum"'
Autor:
L Ren-Heidenreich, L G Lum
Publikováno v:
Current gene therapy. 1(3)
A promising strategy for cancer treatment is adoptive gene therapy/immunotherapy by genetically modifying T lymphocytes with a chimeric receptor (ch-TCR) so that cytotoxic T lymphocytes (CTL) can target and lyse tumors in a MHC-non-restricted manner.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5650bfc14feb47717c32825834115a
https://pubmed.ncbi.nlm.nih.gov/12109140
https://pubmed.ncbi.nlm.nih.gov/12109140
Activated T-cell and bispecific antibody immunotherapy for high-risk breast cancer. Bench to bedside
Publikováno v:
Acta haematologica. 105(3)
Nontoxic approaches are needed to improve overall survival (OS) and progression-free survival (PFS) for high-risk breast cancer. Combination immunotherapy (IT) consisting of activated T cells (ATC), interleukin-2 (IL-2), and CTL (GM-CSF) was given af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05481fe8522f0d181dd28c1a5fb32d51
https://pubmed.ncbi.nlm.nih.gov/11463985
https://pubmed.ncbi.nlm.nih.gov/11463985
Publikováno v:
Human gene therapy. 9(10)
Important considerations for T lymphocyte-based gene therapy include efficient gene delivery and expression in primary, human T cells. In this study, retrovirus-mediated gene transfer and the fate of proviral gene expression were evaluated in human T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9b5033d522ad884e09bb5421ed3b89
https://pubmed.ncbi.nlm.nih.gov/9681410
https://pubmed.ncbi.nlm.nih.gov/9681410
Publikováno v:
Experimental hematology. 23(13)
Although cytokines produced by activated T cells may accelerate immunohematopoietic reconstitution after autologous bone marrow transplantation (ABMT), there is no direct evidence that infusion of anti-CD3 mAb-activated T cells can accelerate engraft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acb9a79b8916688c5b4afc3e89664d3b
https://pubmed.ncbi.nlm.nih.gov/7498359
https://pubmed.ncbi.nlm.nih.gov/7498359
Publikováno v:
Bone marrow transplantation. 16(1)
We previously found that intracellular ionized calcium ([Ca2+]i) flux responses after anti-CD3 crosslinking of CD3/TCR on T cells from allogeneic and autologous bone marrow transplant (BMT) recipients were impaired, Yamagami et al. J Clin Invest 1990
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c23b2ebdba5e0738f10fe5e065dbd7d3
https://pubmed.ncbi.nlm.nih.gov/7581108
https://pubmed.ncbi.nlm.nih.gov/7581108
Autor:
M, Varterasian, V, Ratanatharathorn, C, Karanes, J, Uberti, F, Momin, E, Abella, L G, Lum, L K, Heilbrun, L L, Sensenbrenner
Publikováno v:
Bone marrow transplantation. 15(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62822d6d88adb9cc4d31b6edbfd0aea2
https://pubmed.ncbi.nlm.nih.gov/7773230
https://pubmed.ncbi.nlm.nih.gov/7773230
Autor:
V, Ratanatharathorn, J, Uberti, C, Karanes, E, Abella, L G, Lum, F, Momin, G, Cummings, L L, Sensenbrenner
Publikováno v:
Blood. 84(4)
A prospective comparative trial of allogeneic versus autologous bone marrow transplant (BMT) was conducted. Sixty-six consecutive patients (median age, 41; range, 15 to 60; female:male ratio = 21:45) entered this clinical trial. Priority for allogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcb86e5d8e85fc097d617635c172409f
https://pubmed.ncbi.nlm.nih.gov/8049425
https://pubmed.ncbi.nlm.nih.gov/8049425
Autor:
V, Ratanatharathorn, J, Uberti, C, Karanes, L G, Lum, E, Abella, M E, Dan, M, Hussein, L L, Sensenbrenner
Publikováno v:
Bone marrow transplantation. 13(5)
To explore the augmentation of cyclosporin-induced graft-versus-host disease (GVHD) in autologous bone marrow transplantation (BMT), we conducted a phase I dose escalation trial of interferon (IFN)-alpha 2a. A dose of either 1 or 3 x 10(6) units of I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b66112ccb9d3c4055a1bca5dfbac544
https://pubmed.ncbi.nlm.nih.gov/8054915
https://pubmed.ncbi.nlm.nih.gov/8054915
Autor:
L G, Lum, I D, Joshi, M R, Smith, V, Ratanatharathorn, S C, Galoforo, C, Karanes, J P, Uberti, L L, Sensenbrenner
Publikováno v:
Bone marrow transplantation. 13(2)
The immunodeficiency that occurs after human bone marrow transplantation (BMT) leaves BMT recipients susceptible to fatal infections. Although cytokines are critical for coordinating immune responses and immune reconstitution after BMT, there are sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38544d77decf7adef73265170f472ee0
https://pubmed.ncbi.nlm.nih.gov/8205088
https://pubmed.ncbi.nlm.nih.gov/8205088
Publikováno v:
Transplantation. 56(2)
In order to obtain T cells for adoptive immunotherapy after autologous bone marrow transplantation (ABMT) for patients with resistant hematological malignancies, a culture system was developed for growing T cells and inducing non-MHC-restricted cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9954d2ca7559ce2f59b5620d27ed7dc1
https://pubmed.ncbi.nlm.nih.gov/8356589
https://pubmed.ncbi.nlm.nih.gov/8356589